Neurotransmitters and other chemical signalling agents
| CHOLECYSTOKININ (CCK) (and GASTRIN (G)) | |||
|---|---|---|---|
| Precursors: | Preprocholecystokinin | ||
| Synthesising enzymes: | Post-translational peptidases | ||
| Metabolising enzymes: | Endopeptidase EC 24:11 | ||
| Metabolite: | Peptide fragments | ||
| Receptor subtypes | Agonists | Antagonists | Second messenger |
| CCK(A) | A71378 | Devazepide, lorglumide |
PI |
| CCK(B) | CCK4 | L365260, PD134308 |
? |
| Gastrin * | G17 | L365260 | PI |
* may be identical to CCK(B)
NB: (+ve) indicates increase; (-ve) indicates decrease.
Reviews
Hughes, J. and Woodruff, G. (1991) Ann. Rev. Pharmacol. Toxicol. 31, 469-501.
Dopamine
Bradykinin
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