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Antiarrhythmic agents: (CYP2D6) Poor metabolizers of propafenone have increased t1/2 and max plasma concentrations and higher incidence of neurological side effects
Antiarrhythmic agents: (CYP2D6) Poor metabolizers of propafenone have increased t1/2 and max plasma concentrations and higher incidence of neurological side effects
Morphine derivatives: (CYP2D6) Codeine metabolism affects the efficacy towards pain
Isoniazide (INH): (acetylation) Poor metabolizers at higher risk of peripheral neuropathy