2hbs

Structure viewers   PDB id: 2hbs Oxygen transport Title: The high resolution crystal structure of deoxyhemoglobin s  Structure: Hemoglobin s. Chain: a, b, c, d, e, f, g, h. Synonym: hbs, hemoglobin a (beta6 glu-val). Mutation: chain b, d, f, h, e6v variant. Biological_unit: tetramer  Source: Homo sapiens. Human. Tissue: blood. Cell: red blood cells. Cellular_location: cytoplasm  Resolution: 2.05Å. R-factor: 0.165. R-free: 0.215.  Authors: D.J.Harrington, K.Adachi, W.E.Royer junior  Date: 06-May-97

Links:

SWISS-PROT codes: HBA_HUMAN (Chains: A, C, E, G)   HBB_HUMAN (Chains: B, D, F, H)

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Secondary structure of 2hbs

• Main-chain trace
Chain: A ( 141 residues ) - [K&S: 8 helices ]
Chain: B ( 146 residues ) - [K&S: 9 helices ]
Chain: C ( 141 residues ) - [K&S: 8 helices ]
Chain: D ( 146 residues ) - [K&S: 11 helices ]
Chain: E ( 141 residues ) - [K&S: 8 helices ]
Chain: F ( 146 residues ) - [K&S: 9 helices ]
Chain: G ( 141 residues ) - [K&S: 8 helices ]
Chain: H ( 146 residues ) - [K&S: 10 helices ]
• Ligands (shown as all atoms)
8 x Ligand: HEM
• Metals
8 FE ions

	Molecule(s) in PDB file 2hbs:

Chain A ( 141 residues )

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 10 helices, 4 beta turns, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 10 helices, 4 beta turns, 2 gamma turns.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 9 helices, 6 beta turns, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 12 helices, 1 beta turn, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 10 helices, 4 beta turns, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 10 helices, 4 beta turns, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 9 helices, 6 beta turns, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

• structural classification ( 1 domain) :

Link	CATH no.		Class	Architecture
	1.10.490.10	->	Mainly Alpha	Non-Bundle


• PROMOTIF summary :
 12 helices, 3 beta turns, 1 gamma turn.
• TOPS protein topology cartoon
• - annotated FASTA alignment of related sequences in the PDB
• MolScript picture (PostScript file)

8 x Ligand:HEM - Protoporphyrin ix containing fe [ Heme ] Formula: 8(C34 H32 N4 O4 FE1)

• Schematic diagram of molecule
• Raster3D picture of molecule
• LIGPLOT of interactions

8 Metal ions:_FE ions

573 water molecules.