PHARMACOLOGY 201
THEORY AND PRACTICE OF RECEPTOR CHARACTERIZATION AND DRUG ANALYSIS
Richard Mailman
Jose Boyer

THEORY AND PRACTICE OF RECEPTOR CHARACTERIZATION AND DRUG ANALYSIS
Richard B. Mailman, Ph.D.
Jose Boyer, Ph.D.


Prerequisites
Content
Objectives
Materials
Outline
Grading

Course Prerequisites

Students must have completed course work in biology and chemistry before taking this course.

This course does require the student to have access to a computer, and a proficiency in the use of microcomputers.

Course Content

This course will consist of eight lessons and three workshops.

Each lesson will include specific readings. Students will also be required to participate in a discussion forum during the course.

Course Objectives

The object of this part of the course is to provide the foundation necessary for understanding receptor-ligand (receptor-drug) interactions, and the fundamentals of the techniques commonly employed for such analysis. It is expected that at the end of this section, all students will be able to design and/or interpret studies that characterize either new receptors, or new drugs.

Course Materials
 
TextbooksThe following texts will be most useful for students in this class
    LE Limbird. Cell surface receptors: A Short Course on Theory and Methods, Second Edition. Kluwer Academic Publishers, 1996. 

    HI Yamamura et al. Methods in Neurotransmitter Receptor Analysis, Raven Press, 1990.

    T Kenakin. Pharmacologic Analysis of Drug Receptor Interaction (2nd ed.) Raven Press, 1993.

Internet materials
    E-mail -- Students may communicate with me at any time during the course via e-mail.

Course Outline