Ugo Bastolla (Centro de Astrobiología, Madrid).
Protein thermodynamics
Slide 3
Lattice models
Slide 5
Slide 6
Effective energy for real protein structures
Modeling protein thermodynamics
Methods to derive effective energy functions
PDB structures
Crystal structures
NMR structures
The energy parameters correlate to experimentally measured hydrophobicity
Structure prediction
Protein families
Stability prediction
Slide 17
Normalized energy gap
Slide 19
Genomic characteristics
Statistical analysis of 37 prokariotic genomes
Correlation folding-genome size
Correlation GC-folding
Correlation genome size-GC
The Universal Genetic Code
Bases asymmetries
AT bias as Mutational Bias
AT bias
Interpreting correlations
Evolution of Genome reduction and Mutational bias
Conclusions
Acknowledgements
