Working page

This page URL: http://www.pdg.cnb.uam.es/pagomez/pgp_work.html 
 
 
Cell Division Protein FtsA
 

 

Top

HUMAN GENOME PROJECT


The sixteen institutions that form the Human Genome Sequencing Consortium include:
Baylor College Baylor College of Medicine, Houston, Texas, USA
Beijing HGC Beijing Human Genome Center, Institute of Genetics, Chinese Academy of Sciences, Beijing, China
Braunschweig GBF Gesellschaft für Biotechnologische Forschung mbH, Braunschweig, Germany
Genoscope Genoscope, Evry, France
Waltham GTC Genome Therapeutics Corporation, Waltham, MA, USA
Jena IMB Institute for Molecular Biotechnology, Jena, Germany
Joint Genome Joint Genome Institute, U.S. Department of Energy, Walnut Creek, CA, USA
Keio University Keio University, Tokyo, Japan
Max Planck Max Planck Institute for Molecular Genetics, Berlin, Germany
RIKEN RIKEN Genomic Sciences Center, Saitama, Japan
The Sanger Centre The Sanger Centre, Hinxton, U.K.
Stanford TDC Stanford DNA Sequencing and Technology Development Center, Palo Alto, CA, USA
Washington Univ. Genome Center University of Washington Genome Center, Seattle, WA, USA
Washington Univ. Mult. Seq. Center University of Washington Multimegabase Sequencing Center, Seattle, WA,USA
Whitehead Institute Whitehead Institute for Biomedical Research, MIT, Cambridge, MA, USA
Washington Univ. Genome Seq. Center Washington University Genome Sequencing Center, St. Louis, MO, USA

Computational support and analysis (Consortium):
NCBI The National Center for Biotechnology Information at NIH
EBI The European Bioinformatics Institute in Cambridge, UK

Celera:
Celera Genomics Celera Genomics (A PE Corporation Business) homepage.
Human GenomeTop
 

Non-Human Genome Projects
 
Mouse Mouse Genome Informatics
Microbial The TIGR Microbial Database
Parasite Parasite Genome
Arabidopsis The Arabidopsis cDNA Sequence Analysis Project
Mosquitoes The Mosquito Genomics WWW Server
C. elegans Wormbase
Drosophila Flybase
Rat RATMAP
Saccharomyces Saccharomyces Genome Database
Human GenomeTop
 
 

Top

DNA & GENOME ANALYSIS SYSTEMS

GeneQuiz GeneQuiz is an integrated system for large-scale biological sequence analysis. (EBI)
DANTE DANTE: Viral genomes analysis. (PDG-CNB)
COGs Clusters of Orthologous Groups of proteins: Phylogenetic classification of proteins encoded in complete genomes
GenProtEC GenProtEC: database dedicated to E. coli genome and proteome
MicrobioNet MICROBIONET: Provide information on some of the thousands of forms of bacteria.
TIGR TIGR Microbial Database: microbial genomes completed and in progress
GOLD GOLD: Genomes OnLine Database HomePage
GenomeNet GenomeNet WWW server (KEGG, DBGET, ...)
Beowulf Wellcome Trust Beowulf Genomics Initiative

 

Human genome guides:
NCBI-HumanGenome Human genomic sequence and gene annotation at NCBI.
GoldenPath Human Genome Project Working Draft at University of California at Santa Cruz.
Ensembl Ensembl, a joint human genome annotation project of the EBI and the Sanger Centre.

 
MBS MBS - Molecular Biology On-line tools selection
Bio-Web The Bio-Web: DNA and Protein Sequence Analysis Tools
FBS  FRONTIERS IN BIOSCIENCE; DNA/RNA ANALYSIS TOOLS
Deambulum The DEAMBULUM (Computing applied to biomolecules and genomes) : nucleic acid sequence analysis
Adelaide A Pack of Molecular Analysis Tools. Adelaide University

 
 
 

Top

PROTEIN ANALYSIS

ExPASy  ExPASy Proteomics Tools: A collection of tools for DNA and Protein analysis and manipulation (ExPASy, Switzerland)
PIR  Protein Information Resource Home Page (Georgetown University)
BIOWEB Biological software at the Institut Pasteur (Blast, ClustalW, Phylip, HMM, and much more) (France)

 Sequence search / alignments.

SRS5 - EMBL SRSWWW server at EMBL, Heidelberg, Germany. , version 5.1.0
SRS6 - CNB SRSWWW server at EMBnet/CNB , version 6.0.7.2
SRS6-EBI SRSWWW server at EBI, Hinxton, UK., version 6.0.6
MORE PUBLIC SRS SERVERS Links to public SRS servers, libraries and applications.
Swiss-Prot Access to SWISS-PROT and TrEMBL (ExPASy, CH)

 
ORF Finder Open Reading Frame Finder (NCBI)
Blast2_EMBL WU-BLAST2 search at EMBL (blast 2.0 with gaps)
Blast2_EBI WU-BLAST2 search at EBI (blast 2.0 with gaps)
Blast2_NCBI Basic/Advanced BLAST2  (blastall)  search at NCBI
Blast2_ISREC Advanced BLAST2 search at ISREC, CH
Blast Unfinished Blast to Unfinished microbial genomes at NCBI
Blast2_nrdb90 Similarity search by against nrdb90 (at EBI)
ProtEST Search the Expressed Sequence Tag database (EBI)
Psi-Blast_NCBI Psi-Blast at NCBI
FASTA3_EBI FASTA3 at EBI
FDF Fast Data Finder (Smith-Waterman) at ISREC
WWW-Query WWW-Query: Keyword + ClustalW search and alignment (PBIL in Lyon, France)
Search and Cluster Recursive BLAST-searches and NCUT-clustering (PDG-CNB)

 
BLAST 2 sequences BLAST 2 sequences against each other (at NCBI)
SIM Alignments between two protein sequences or within a sequence (ExPASy, CH)

 
ClustalW_EMBL CLUSTAL W (1.75) Multiple Sequence Alignments (EMBL-ES)
ClustalW_EBI ClustalW Server at EBI
ClustalW_BioWeb ClustalW Server at  the Institut Pasteur (France)
T-COFFEE T-Coffee: Accurate, but slow, Multiple Sequence Alignment server (EMBNET.CH) (limit: 30 seq, 1000 res)
T-COFFEE T-Coffee:  Cedric Notredame page (University of Nijmegen, NL) (limit: 20 seq 300 res)
CMBI_Tree_Plot CMBI Phylogenetic Tree Plot Server (University of Nijmegen, NL) (GIF, PS,.. trees)
Phylodendron Phylodendron: Phylogenetic tree printer (EMBL-ES)
PHYLIP PHYLIP is a free package of programs for inferring phylogenies (Whasington Univ.)
WebPHYLIP WebPHYLIP is a web version of the original PHYLIP package.  National University of Singapore.
BioWebPHILIP PHILIP (web version) at the Institut Pasteur (France)
PAUP PAUP is a software package for inference of evolutionary trees (Florida Stat. Univ.)
Philogeny Programs Here are some 193 of the phylogeny packages, and 16 free servers.
Phylogeny Course Molecular Systematics and Evolution Course (London - Rio de Janeiro)
Gene Prediction A collection of tools suitable for gene prediction (EMBL)
EBI Services Database Searching, Browsing and Analysis Tools (EBI)
ExPASy Tools ExPASy Proteomics tools
AQUA AQUA - Alignment Quality Assessment (EMBL)

 
SAM_Home SAM: Sequence Alignment and Modeling System (HMM)
SAM_applications UCSC HMM Applications
ISMB99 tutorial on using HMMs  Making the most of your hidden Markov models
HMMER (restricted) HMMER 2.1.1  Profile hidden Markov models for biological sequence analysis
HMMER at BioWeb  HMMER : using HMM (Hidden Markov Model) (Sean Eddy) at the Institut Pasteur (France)
NAIL Network Analysis Interface for Linking HMMER results (EMBL)
Protein analysisTop

Primary structure.
 
Prosite ProfileScan Server (ISREC, CH)
ProDom ProDom protein domain database (INRA, FR)
InterPro Integrated resource of protein domains and functional sites. (EBI, UK)
PFAM Protein families database of alignments and HMMs (Sanger, UK)
DART Domain Architecture Retrieval Tool  (It shows similar domain achitectures, too) (NCBI)
PRINTS Protein Motif Fingerprint Database (UCL, UK)
SMART Simple Modular Architecture Research Tool. Domains/motif  detection (EMBL)
Blocks/Prints Searching both Blocks+ and Prints databases (FHCRC, USA)
SignalP Predicts the presence and location of signal peptide (CBS, DK)

 
PredictProtein The PredictProtein server  (Columbia, USA)
PredictProtein (local) The PredictProtein server  (EMBnet / CNB, ES)
ExPASy Tools ExPASy Proteomics tools
Protein analysisTop

Protein families / classification.
 
COG Phylogenetic classification of proteins encoded in complete genomes (NCBI)
ProtoMap An automatic hierarchical classification of all swissprot proteins
Search and Cluster  Recursive BLAST-searches and NCUT-clustering (PDG-CNB)
Protein Kinases Web accessible compendium of information on the protein kinase family of enzymes.

 
PFAM Protein families database of alignments and HMMs (Sanger, UK)
InterPro Integrated resource of protein domains and functional sites. (EBI, UK)
ProDom ProDom protein domain database (INRA, FR)
Protein analysisTop

Secondary structure.
 
EVAsec   EVA (evaluation of protein structure prediction servers in 'real time'): secondary structure
TMHMM Prediction of transmembrane helices in proteins (CBS, DK)
HMMTOP Prediction of transmembrane helices and topology of proteins (Inst. Enzymol. Budapest)
SignalP Predicts the presence and location of signal peptide (CBS, DK)
COILS Prediction of Coiled Coil Regions in Proteins (ISREC, CH)
MultiCoil Program for Predicting Two- and Three-Stranded Coiled Coils (MIT, USA)
Jpred A consensus method for protein secondary structure prediction (EBI, UK)
Psi-Pred Protein structure prediction server  (secondary structure & transmembrane topology) (University College London, UK)
APSSP APSSP: Advanced Protein Secondary Structure Prediction Server (Chandigarh, INDIA)
TOPS Protein Topology Home Page (EBI, UK)
SAM-T99 SAM-T99 secondary structure prediction. 
PredictProtein The PredictProtein server  (Columbia, USA)
PredictProtein (local) The PredictProtein server  (EMBnet / CNB, ES)
ExPASy Tools ExPASy Proteomics tools
Protein analysisTop

3D structure / Modeling / Threading

Homology modelling:
 
EVA-cm   EVA (evaluation of protein structure prediction servers in 'real time'): comparative modeling
Swiss-Model SWISS-MODEL. An Automated Comparative Protein Modelling Server (ExPASy, CH)
SWISS-MODEL Repository SWISS-MODEL Repository. A database for theoretical protein models (ExPASy, CH)
WHATIF WHAT IF  Web interface:  homology modelling, drug docking, electrostatics calculations, structure validation and visualisation.
TITO/Modeller Modeller at the CBS Bioinformatic Tools Server (Montpellier, France)
CPHmodels   The CPHmodels Server using comparative (homology) modelling (BioCentrum, Denmark)
SDSC1 "SDSC1" - SDSC Protein Structure Homology Modeling Server (San Diego, USA)

Threading:
 
EVAfr   EVA (evaluation of protein structure prediction servers in 'real time'): threading
PredictProtein The PredictProtein server (TOPITS) (Columbia, USA)
PredictProtein (local) The PredictProtein server (TOPITS) (EMBnet / CNB, ES)
3D-PSSM 3D-PSSM Protein Fold Recognition (Threading) Server (Imperial Cancer Res. Fund., UK)
UCLA-DOE UCLA-DOE Fold-Recognition server (UCLA, USA)
Psi-Pred (GenThreader) Protein structure prediction server  (sequence profile based fold recognition) (University College London UK)
SAM-T99 SAM-T99 protein structure HMM library search.
FFAS Fold & Function Assignment System. (Burnham Institute, USA)
Fold-Pred Protein Fold Prediction in the context of SCOP.
FUGUE FUGUE Profile Library Search Against HOMSTRAD (Cambridge, UK)
Threading Meta-Server Threading Meta-Server at the CBS Bioinformatic Tools Server (Montpellier, France)
Threading Meta-Server Threading Meta-Server at BioInfo.PL (Warszawa, Poland)
SAUSAGE   SAUSAGE: Protein threading with flexible force fields (Canberra, Australia)
LOOPP A program for potential optimization and alignments (Cornell, USA)
Superfamily HMM library and genome assignments server (Cambridge, UK)

Structure validation:
AQUA AQUA - Alignment Quality Assessment
BIOTECH Validation Suite Biotech Validation Suite for Protein Structures (PROCHECK, PROVE & WHAT IF)
WHATIF WHAT IF  Web interface:  homology modelling, drug docking, electrostatics calculations, structure validation
and visualisation.
3D Evaluation Verify3D & PROSA II at the CBS Bioinformatic Tools Server (Montpellier, France)

Databases:
PDB - EBI Protein Data Bank (EBI)
PDB - RCSB Protein Data Bank (RCSB)
PDBsum Summaries and structural analyses of PDB data files (UCL, UK)
Get ExPDB Get ExPDB entries for a PDB code (Swiss-Model, ExPASy, CH)
OCA PDB advanced browser(EBI)
PDBselect Subset of the structures in the PDB that does not contain (highly) homolog sequences
EC->PDB Enzyme Structures deposited in PDB (UCL, UK)
Prosite->PDB PROSITE patterns in PDB entries (UCL, UK)
Ligands->PDB List of ligands bound to PDB srtuctures (UCL, UK)
RELIBASE Relibase: A program for searching protein-ligand databases.
Molecular Models 1400 Molecular Models (from chemistry) in .pdb format (Okanagan University College, Canada)
NDB The Nucleic Acid Database Project (UK) (Nucleic Acid Structures)
IMB Jena IMB Jena Image Library of Biological Macromolecules (Jena, Germany)
CORINA CORINA: A powerful and reliable tool for the generation of 3D atomic coordinates (Erlangen, Germany)
Structural Genomics Targets Targets For NIH Structural Genomics Projects (SEARCH for sequences)
SCOP Structural Classification of Proteins (MRC-LMB, UK)
CATH CATH Protein Structure Classification (UCL-BSM, UK)
The Dali server The Dali server: Network service for comparing protein (query) structures in 3D (EBI)
WWWSUP Pairwise Superposition of Protein 3D Structures (CIGB, Habana, Cuba)
FSSP Fold classification based on Structure-Structure alignment of Proteins (FSSP) (EBI)
DaliDD Dali Domain Dictionary: structural classification of protein domains (EBI)
Homstrad Homologous Structure Alignment Database (CrystBioc, UK)
3Dee 3 Dee - A Database of Protein Domain Definitions (EBI)
CAMPASS CAMbridge database of Protein Alignments organised as Structural Superfamilies (CrystBioc, UK)
ProSup Structure Comparison Server (Manfred J. Sippl - CAME)
Protein analysisTop

Contacts & Quaternary structure
 
EVAcon   EVA (evaluation of protein structure prediction servers in 'real time'): inter-residue contacts
CORNET Prediction of Residue Contacts in Proteins (CIRB Biocomputing Group, Bologna Univ. Italy)
PDGCON The threading server page from the Protein Design Group at the CNB (Madrid, Spain)
SPIN-PP  Surface Properties of INterfaces - Protein Protein Interfaces (Columbia Univ. USA)
PQS  Protein Quaternary Structure Database Searches at the EBI
NDB The Nucleic Acid Database Project (UK) (Protein/Nucleic Acid Complexes)
Protein analysisTop

Direct links to databases
 
EBI SRS BookmartLet (info) for:
PROTEIN SEQ.
DNA/RNA SEQ.

NiceProt View of SWISS-PROT (IC or AC) (i.e. DNAB_ECOLI) -> 
OPEN 
NiceZyme View of ENZYME (EC number) (i.e. 2.1.1.21)-> 
OPEN 
ProDom sharing-domain group (SWISS-PROT IC or AC; i.e. SRC1_XENLA)-> 
OPEN 
InterPro Entry (i.e. IPR002965)-> 
OPEN 
InterPro Entry of SWISS-PROT AC (i.e. O15142)-> 
OPEN 
SwissPfam entry (SWISS-PROT IC or AC; i.e. PIP4_BOVIN)-> 
OPEN 
Pfam Protein Family entry (family code; i.e. PF00158)-> 
OPEN 
PDBsum summary of PDB entry (4 characters code; i.e. 2hbs) -> 
OPEN 
OCA atlas summary of PDB entry (4 characters code; i.e. 1bj5) -> 
OPEN 
Aminoacids sequence of PDB entry (4 characters code; i.e. 1fmo) -> 
OPEN 
CATH search results (4 characters code; i.e. 2bnh) -> 
OPEN 
SCOP classification (4 characters code; i.e. 1av1) -> 
OPEN 
FSSP: search for PDB entry (4 characters code; i.e. 2pgd) -> 
OPEN 

 
 

Top

METABOLISM

KEGG KEGG:Kyoto Encyclopedia of Genes and Genomes (ICR, JP)
WIT What Is There?: Interactive Metabolic Reconstruction (MCS/ANL, USA)
BM Pathways Boehringer Mannheim´s Biochemical Pathways (ExPASy, CH)
MetaCyc MetaCyc: Metabolic Encyclopedia (Pangea Systems, USA)
UM-BBD The University of Minnesota Biocatalysis/Biodegradation Database (USA)

 
 
 

Top

VIROLOGY

Flu Sequence Database Influenza Sequence Database (Los Alamos National Lab., CA)
All the Virology All the Virology on the WWW (links, pictures and much more...)
ICTV The International Committee on Taxonomy of Viruses
ICTVdb ICTVdb: The Universal Virus Database (NCBI)
ICTVdb (UK) ICTVdb: The Universal Virus Database (UK mirror)
Index Virum ICTVdB - INDEX VIRUM: Catalogue of Viruses (NCBI)
Index Virum (UK) ICTVdB - INDEX VIRUM: Catalogue of Viruses (UK mirror)
Virus Images ICTVdB - Picture Gallery (NCBI)
SEV Spanish Society of Virology
IMV Institute for Molecular Virology (Wisc., USA)

 
 

Top

BIBLIOGRAPHY

PubMed PubMed is the National Library of Medicine's search service 
BioMedNet medline BioMedNet - your science (Elsevier Science) Medline search.
OPAC C.S.I.C. Libraries Network Catalog.
Abbreviations List of journals abbreviations.
Journal Impact Factor Journal Impact Factor (BIOREFERENCE)

 
Science The EMBO Journal FEBS Letters
Nature EMBO reports Journal of Virology
Nature Biotecnology Journal of Biological Chemistry Journal of General Virology
Nature Cell Biol. Annual Reviews Virology 
Nature Genetics Molecular Cell   
Nature Struct. Biol. Molecular and Cellular Biology  Molecular Microbiology
Cell Nucleic Acid Research  
Proc. Natl. Acad. Sci. USA Current Opinions Online  

 
Protein Science Journal of Molecular Biology Bioinformatics
Protein Engineering Journal of Molecular Evolution (BBA)/Prot. Struc. & Mol. Enzymol.
Genome Informatics Proteins: structure, function and genetics Journal of Structural Biology

 
 

Top

Statistics / Programming

MathWorld  Eric Weisstein's World of Mathematics
StatSoft  StatSoft: Electronic Statistics Textbook 

 
Graph Algorithms Graph Algorithms Applet (RIOT, USA)
Mol. Biol. Algorithms Algorithms in Molecular Biology (Course)
The Stony Brook Algorithm Repository A comprehensive collection of algorithm implementations (NY Univ)
Principal component analysis Principal component analysis -Praat- tutorial  (Amsterdam Univ)
NP optimization A compendium of NP optimization problems
Computational Mol Biol Computational Molecular Biology course
BioComputing Coursebook BioComputing Hypertext Coursebook
Statistics of Seq. Similarity The Statistics of Sequence Similarity Scores (NCBI)
Statistics & life sciences Statistics for the life sciences (Course)
Seq. Analysis COURSES In-House Sequence Analysis Courses at EMBL

 
EMBnet/CNB Computing Library EMBnet/CNB Computing Library (manuals, courses, FAQs and more)
RDB RDB: a Relational Database Management System

 
UNIX manpage UNIX Manpage viewer (local)
UNIX menu A menu of  UNIX major topics (local)
UNIX ref. desk The UNIX Reference Desk
UNIX commands Useful UNIX Commands - A short list

 
Perl5 Guide Rex Swain's HTMLified Perl 5 Reference Guide
Perl Journal The Perl Journal online
Perl Manual Perl manual at MIT
www.perl.com The Source for Perl - Home Page
Perl tutorials Perl tutorials at www.perl.com
Learn Perl Take 10 Minutes to Learn - PERL 
El evangelio de Perl Perl tutorial (castellano)

 
HTML: guide Bare Bones Guide to HTML -- download page
HTML: color chart Dougie´s Color Picker for HTML (RGB Hex Triplet Color Chart)
HTML: tags Otmar´s list of HTML Tags

 
 

Top

MISCELLANY

Tree of Life The Tree of Life Home Page. (Arizona Univ, USA)
Chemical Elements.com  Chemical Elements.com - An Interactive Periodic Table of the Elements

 
 
Biocatalog A software directory of general interest in molecular biology and genetic. (EBI)
BioMedNet BioMedNet - your science (Elsevier Science)
Pedro´s Pedro's Research Tools 

 
GenProtEC GenProtEC: database dedicated to E. coli genome and proteome
MicrobioNet MICROBIONET: Provide information on some of the thousands of forms of bacteria.
TIGR TIGR Microbial Database: microbial genomes completed and in progress
GOLD GOLD: Genomes OnLine Database HomePage
GenomeNet GenomeNet WWW server (KEGG, DBGET, ...)
Beowulf Wellcome Trust Beowulf Genomics Initiative
GeneQuiz Genome analyses with GeneQuiz 

 
RNA Structure Prediction The Zuker Lab: RNA Secondary Structure (CCB/WUSTL, USA)
The RNA World The RNA World website at IMB Jena Biocomputing Group (DE)
Vienna RNA Vienna RNA Package: RNA Secondary Structure Prediction (UNIVIE, AT)

Top
 


Last update: March, 2002
Paulino Gomez-Puertas, Ph.D.
Protein Design Group.
Centro Nacional de Biotecnologia - C.S.I.C.
Campus de la Universidad Autonoma de Madrid.
Cantoblanco, 28049 Madrid. SPAIN.
Tel: (+34) 91 585 4839/4669.  Fax: (+34) 91 585 4506
e-mail: pagomez@cnb.uam.es