AACompSim tool

AACompSim is a tool which allows the comparison of the amino acid composition of a SWISS-PROT entry with all other SWISS-PROT entries so as to find the proteins whose amino acid compositions are closest to that of the selected entry [references].

Documentation is available.

You will have to enter the following data:

A SWISS-PROT identifier (ID) (e.g. ALBU_HUMAN) or SWISS-PROT accession number (AC) (e.g. P04406).
Your e-mail address. The search results will be mailed back to you automatically (this should take less than 15 minutes).
The SWISS-PROT abbreviation for the species for which you would like to perform the search (example: HUMAN). This will produce the list of proteins from this species, as well as a list of proteins independently of species; you may also specify ALL for all SWISS-PROT entries.

Few amino acid analysis techniques produce composition results for all amino acids. We currently have indexed SWISS-PROT for the following constellations. Please choose one of them:

Constellation 0: ALL amino acids: Ala, Ile, Pro, Val, Arg, Leu, Ser, Thr, Gly, Met, His, Phe, Tyr, Lys, Asp, Asn, Gln, Glu, Cys and Trp.
Constellation 1: Ala, Ile, Pro, Val, Arg, Leu, Ser, Asx, Thr, Glx, Gly, Met, His, Phe and Tyr.
(Asp+Asn=Asx; Gln+Glu=Glx; Lys, Cys and Trp are not considered).
Constellation 2: Ala, Ile, Pro, Val, Arg, Leu, Ser, Asx, Lys, Thr, Glx, Gly, Met, His, Phe and Tyr.
(Asp+Asn=Asx; Gln+Glu=Glx; Cys and Trp are not considered).
Constellation 3: Ala, Ile, Pro, Val, Arg, Leu, Ser, Asx, Lys, Thr, Glx, Gly, Met, His and Phe.
(Asp+Asn=Asx; Gln+Glu=Glx; Tyr, Cys and Trp are not considered).

If you would like to use another amino acid constellation, please send us an e-mail, we will try to index SWISS-PROT according to your needs.

Last modified 4/Jun/1998 by CHH

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