BLASTP2 Result
of 
Bork Group's Advanced BLAST2 Search Service at 
EMBL.
back to BLAST2
BLASTP 2.0MP-WashU [16-Dec-1999] [irix6-r10k-L64 23:35:48 16-Dec-1999]
Copyright (C) 1996-1999 Washington University, Saint Louis, Missouri USA.
All Rights Reserved.
Reference: Gish, W. (1996-1999) http://blast.wustl.edu
Query= ice2_human
(89 letters)
Database: nrdb-95%
701,238 sequences; 229,823,634 total letters.
Searching....10....20....30....40....50....60....70....80....90....100% done
Query sequence and locally-aligned HSPs from database sequences
0 20 40 60 80
| | | | | |89
ice2_human | __________________________________________________
^ v swissnew|P42575|IC | __________________________________________________
^ v trembl|U13022|HS13 | __________________________________________________
^ v sptrembl|Q8K241|Q8 | __________________________________________________
^ v sptrembl|Q9WUI6|Q9 | __________________________________________________
^ v trembl|U64963|GGU6 | _________________________________________________
^ v swissnew|P55215|IC | ______________________________
^ v sptremblnew|AAH450 | _____________________________________________
^ v sptrembl|Q9IB67|Q9 | _____________________________________________
^ v swiss|O88843|CRAD_ | ________________________________________
^ v swissnew|P78560|CR | ________________________________________
^ v sptrembl|Q9IB63|Q9 | ______________________________________________
^ v pironly|T20038|T20 | ____________________________________________
^ v swissnew|P45436|CE | __________________________________________
^ v swissnew|P42573|CE | ____________________________________________
^ v trembl|AX082238|AX | _______________________________________________
^ v swissnew|O95999|BC | __________________________________________
^ v swissnew|Q9Z0H7|BC | __________________________________________
^ v swissnew|Q62210|BI | _____________________________________________
^ v sptrembl|Q9QZC6|Q9 | _______________________________________
^ v sptrembl|Q66677|Q6 | ____________________________________________
^ v trembl|AX082236|AX | _______________________________________________
^ v trembl|AX098236|AX | ______________________________________________
^ v sptrembl|Q9W199|Q9 | ____________________________________
^ v sptrembl|Q9YJN5|Q9 | ____________________________________________
^ v swissnew|Q8SL86|RP | ___________________________________________
^ v swissnew|Q9Y2G2|CA | _______________________________________
^ v sptremblnew|AAO246 | ______________________________________________
^ v swissnew|Q13490|BI | _______________________________________
^ v sptrembl|Q8UWD2|Q8 | ______________________________________________
^ v sptrembl|Q9BYX4|Q9 | ______________________________________________
^ v swissnew|Q9Y239|CA | _______________________________________________
^ v swiss|O62640|PIAP_ | __________________________________________
^ v swissnew|Q9I9H8|AP | ____________________________________________
^ v swissnew|Q08346|PR | ___________________________
^ v swissnew|Q980E8|GC | ________________________________
^ v sptrembl|Q8KQ40|Q8 | ____________________________
^ v sptrembl|Q31620|Q3 | ____________________________
^ v trembl|AX089771|AX | _______________________________________
^ v trembl|AX089769|AX | _______________________________________
^ v sptrembl|Q8R8A7|Q8 | _________________________________
^ v sptrembl|Q9HY73|Q9 | _______________________________________________
^ v sptrembl|Q9Y1U6|Q9 | _____________________________________
^ v swissnew|P58801|RI | __________________________________________
^ v sptrembl|Q9XHU8|Q9 | ___________________________
^ v sptrembl|Q90WU0|Q9 | _______________
^ v sptrembl|Q8NLI1|Q8 | ______________________________________________
^ v sptrembl|Q8K5C7|Q8 | __________________________________
^ v swissnew|O43353|RI | ____________________________________________
^ v sptrembl|Q9XHU4|Q9 | ___________________________
^ v swissnew|Q13489|BI | ________________________________________
Alignments:
^ = swissnew|P42575|ICE2_HUMAN Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1
protease) (ICH- 1L/1S).//:swiss|P42575|ICE2_HUMAN Caspase-2
precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH-
1L/1S).//:sptremblnew|AAO25653|AAO25653 Caspase 2,
apoptosis-related cysteine protease (neural precursor cell
expressed, developmentally down-regulated
2).//:tremblnew|AY219042|AY219042_1 gene: "CASP2"; product:
"caspase 2, apoptosis-related cysteine protease (neural precursor
cell expressed, developmentally down-regulated 2)"; Homo sapiens
caspase 2, apoptosis-related cysteine protease (neural precursor
cell expressed, developmentally down-regulated 2) (CASP2) gene,
complete cds. //:trembl|U13021|HS13021_1 gene: "Ich-1"; product:
"ICH-1L"; Human positive regulator of programmed cell death ICH-1L
(Ich-1) mRNA, complete cds. //:pironly|A54821|A54821 apoptosis
regulator ICH-1, stimulatory form L - human//:gp|U13021|537292
ICH-1L [Homo sapiens]//:gp|AY219042|27978962 caspase 2,
apoptosis-related cysteine protease (neural precursor cell
expressed, developmentally down-regulated 2) [Homo sapiens]
Length = 435
0 90 180 270 360
| | | | | |435
swissnew|P42575|ICE2_ | __________________________________________________
Local hits (HSPs) | __________
Score = 448 (162.8 bits), Expect = 4.7e-42, P = 4.7e-42
Identities = 89/89 (100%), Positives = 89/89 (100%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP
Sbjct: 16 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 75
Query: 61 KRGPQAFDAFCEALRETKQGHLEDMLLTT 89
KRGPQAFDAFCEALRETKQGHLEDMLLTT
Sbjct: 76 KRGPQAFDAFCEALRETKQGHLEDMLLTT 104
^ = trembl|U13022|HS13022_1 gene: "Ich-1"; product: "ICH-1S"; Human negative
regulator of programmed cell death ICH-1S (Ich-1) mRNA, complete
cds. //:trembl|AX134407|AX134407_1 unnamed ORF; Sequence 3 from
Patent WO0129232. //:pironly|B54821|B54821 apoptosis regulator
ICH-1, suppressive form S - human//:gp|U13022|537294 ICH-1S [Homo
sapiens]//:gp|AX134407|14271054 unnamed protein product [Homo
sapiens]
Length = 312
0 70 140 210 280
| | | | | |312
trembl|U13022|HS13022 | __________________________________________________
Local hits (HSPs) | _______________
Score = 448 (162.8 bits), Expect = 4.7e-42, P = 4.7e-42
Identities = 89/89 (100%), Positives = 89/89 (100%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP
Sbjct: 2 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 61
Query: 61 KRGPQAFDAFCEALRETKQGHLEDMLLTT 89
KRGPQAFDAFCEALRETKQGHLEDMLLTT
Sbjct: 62 KRGPQAFDAFCEALRETKQGHLEDMLLTT 90
^ = sptrembl|Q8K241|Q8K241 Caspase 2.//:trembl|BC034262|BC034262_1 product:
"caspase 2"; Mus musculus, caspase 2, clone MGC:25295
IMAGE:4460089, mRNA, complete cds. //:trembl|Y13085|MMCASP2_1
product: "caspase-2"; M.musculus mRNA for caspase-2
//:trembl|D28492|MMNEDD_1 gene: "Nedd2"; product: "caspase-2"; Mus
musculus mRNA for caspase-2, complete cds. //:gp|D28492|3090430
caspase-2 [Mus musculus]//:gp|Y13085|2094808 caspase-2 [Mus
musculus]//:gp|BC034262|21706481 caspase 2 [Mus musculus]
Length = 452
0 90 180 270 360 450
| | | | | |452
sptrembl|Q8K241|Q8K24 | __________________________________________________
Local hits (HSPs) | _________
Score = 426 (155.0 bits), Expect = 1.0e-39, P = 1.0e-39
Identities = 85/89 (95%), Positives = 87/89 (97%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
HP HQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAK GSFSQNVELLNLLP
Sbjct: 33 HPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKGGSFSQNVELLNLLP 92
Query: 61 KRGPQAFDAFCEALRETKQGHLEDMLLTT 89
KRGPQAFDAFCEALRET+QGHLED+LLTT
Sbjct: 93 KRGPQAFDAFCEALRETRQGHLEDLLLTT 121
^ = sptrembl|Q9WUI6|Q9WUI6 Caspase-2s.//:trembl|AF136232|AF136232_1 product:
"caspase-2s"; Rattus norvegicus caspase-2s mRNA, complete cds.
//:gp|AF136232|4928692 caspase-2s [Rattus norvegicus]
Length = 343
0 70 140 210 280
| | | | | |343
sptrembl|Q9WUI6|Q9WUI | __________________________________________________
Local hits (HSPs) | ____________
Score = 426 (155.0 bits), Expect = 1.0e-39, P = 1.0e-39
Identities = 85/89 (95%), Positives = 87/89 (97%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
HP HQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAK GSFSQNVELLNLLP
Sbjct: 33 HPDHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKGGSFSQNVELLNLLP 92
Query: 61 KRGPQAFDAFCEALRETKQGHLEDMLLTT 89
KRGPQAFDAFCEALRET+QGHLED+LLTT
Sbjct: 93 KRGPQAFDAFCEALRETRQGHLEDLLLTT 121
^ = trembl|U64963|GGU64963_1 gene: "ich-1"; product: "cysteine protease
caspase-2"; Gallus gallus cysteine protease caspase-2 (ich-1)
mRNA, partial cds. //:gp|U64963|1490878 cysteine protease caspase-2
[Gallus gallus]
Length = 428
0 90 180 270 360
| | | | | |428
trembl|U64963|GGU6496 | __________________________________________________
Local hits (HSPs) | __________
Score = 337 (123.7 bits), Expect = 2.7e-30, P = 2.7e-30
Identities = 64/87 (73%), Positives = 77/87 (88%)
Query: 3 HHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKR 62
+HQE LKKNRV+LA++L+L EL+EH++EKDIIT+EM E+IQAK GSFSQNVE LNLLPKR
Sbjct: 14 YHQEALKKNRVMLARELVLKELMEHMIEKDIITIEMVEMIQAKSGSFSQNVEFLNLLPKR 73
Query: 63 GPQAFDAFCEALRETKQGHLEDMLLTT 89
GP AF AFCEAL+ETKQ HL +M+L T
Sbjct: 74 GPNAFSAFCEALQETKQQHLAEMILKT 100
^ = swissnew|P55215|ICE2_RAT Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1
protease) (Fragment).//:swiss|P55215|ICE2_RAT Caspase-2 precursor
(EC 3.4.22.-) (CASP-2) (ICH-1 protease) (Fragment).
Length = 312
0 70 140 210 280
| | | | | |312
swissnew|P55215|ICE2_ | __________________________________________________
Local hits (HSPs) | _________
Score = 264 (98.0 bits), Expect = 1.5e-22, P = 1.5e-22
Identities = 52/55 (94%), Positives = 54/55 (98%)
Query: 35 TLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTT 89
TLEMRELIQAK GSFSQNVELLNLLPKRGPQAFDAFCEALRET+QGHLED+LLTT
Sbjct: 1 TLEMRELIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALRETRQGHLEDLLLTT 55
^ = sptremblnew|AAH45046|AAH45046 Hypothetical
protein.//:tremblnew|BC045046|BC045046_1 product: "Unknown (protein
for MGC:53258)"; Xenopus laevis, clone MGC:53258 IMAGE:5569848,
mRNA, complete cds. //:gp|BC045046|27924349 Unknown (protein for
MGC:53258) [Xenopus laevis]
Length = 419
0 90 180 270 360
| | | | | |419
sptremblnew|AAH45046| | __________________________________________________
Local hits (HSPs) | __________
Score = 216 (81.1 bits), Expect = 6.8e-17, P = 6.8e-17
Identities = 41/80 (51%), Positives = 56/80 (70%)
Query: 3 HHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKR 62
HH++ L++ RV LA ++++ ELL+HL+ +I+T M I A ++QNV LLNLLPKR
Sbjct: 8 HHRKALQRLRVSLASEMIIEELLDHLVSSEILTNNMHSNIMAYRSDYAQNVALLNLLPKR 67
Query: 63 GPQAFDAFCEALRETKQGHL 82
GP+AF AFC AL T Q HL
Sbjct: 68 GPRAFSAFCNALHSTNQEHL 87
^ = sptrembl|Q9IB67|Q9IB67 Caspase-2.//:trembl|AB038168|AB038168_1 gene:
"xCaspase-2"; product: "caspase-2"; Xenopus laevis mRNA for
caspase-2, complete cds. //:gp|AB038168|7619900 caspase-2 [Xenopus
laevis]
Length = 423
0 90 180 270 360
| | | | | |423
sptrembl|Q9IB67|Q9IB6 | __________________________________________________
Local hits (HSPs) | __________
Score = 216 (81.1 bits), Expect = 7.1e-17, P = 7.1e-17
Identities = 41/80 (51%), Positives = 56/80 (70%)
Query: 3 HHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKR 62
HH++ L++ RV LA ++++ ELL+HL+ +I+T M I A ++QNV LLNLLPKR
Sbjct: 8 HHRKALQRLRVSLASEMIIEELLDHLVSSEILTNNMHSNIMAYRSDYAQNVALLNLLPKR 67
Query: 63 GPQAFDAFCEALRETKQGHL 82
GP+AF AFC AL T Q HL
Sbjct: 68 GPRAFSAFCNALHSTNQEHL 87
^ = swiss|O88843|CRAD_MOUSE DEATH domain containing protein CRADD (Caspase and
RIP adaptator with DEATH domain) (RIP associated protein with a
DEATH domain).//:sptremblnew|AAH05608|AAH05608 CASP2 and RIPK1
domain containing adaptor with death
domain.//:sptremblnew|AAN84619|AAN84619
CRADD.//:tremblnew|AE016753|AE016753_2 gene: "Cradd"; product:
"CRADD"; Mus musculus chromosome 10 high-growth region, section 1
of 2 of the complete sequence. //:trembl|BC005608|BC005608_1
product: "CASP2 and RIPK1 domain containing adaptor with death
domain"; Mus musculus, CASP2 and RIPK1 domain containing adaptor
with death domain, clone MGC:5736 IMAGE:3498522, mRNA, complete
cds. //:trembl|AJ224738|MMAJ4738_1 gene: "Raidd/Cradd"; product:
"death adaptor molecule"; Mus musculus mRNA for death adaptor
molecule (Raidd/Cradd), clone 6-1 //:trembl|AJ224740|MMAJ4740_1
gene: "Raidd/Cradd"; product: "death adaptor molecule"; Mus
musculus mRNA for death adaptor molecule (Raidd/Cradd), I.M.A.G.E
clone 407755, //:gp|AJ224738|3929836 death adaptor molecule [Mus
musculus]//:gp|AJ224740|3929840 death adaptor molecule [Mus
musculus]//:gp|BC005608|13542814 CASP2 and RIPK1 domain containing
adaptor with death domain [Mus musculus]//:gp|AE016753|26251312
CRADD [Mus musculus]
Length = 199
0 40 80 120 160
| | | | | |199
swiss|O88843|CRAD_MOU | __________________________________________________
Local hits (HSPs) | ___________________
Score = 110 (43.8 bits), Expect = 4.5e-06, P = 4.5e-06
Identities = 24/73 (32%), Positives = 47/73 (64%)
Query: 5 QETLKKNRVVLAKQLLLSEL-LEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRG 63
++ L+ R+ L ++L+ L L++L ++ I+T + I+A+ + + LL++LP RG
Sbjct: 6 KQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEIKAQTTGLRKTMLLLDILPSRG 65
Query: 64 PQAFDAFCEALRE 76
P+AFD F ++L+E
Sbjct: 66 PKAFDTFLDSLQE 78
^ = swissnew|P78560|CRAD_HUMAN DEATH domain containing protein CRADD (Caspase
and RIP adaptator with DEATH domain) (RIP associated protein with a
DEATH domain).//:swiss|P78560|CRAD_HUMAN DEATH domain containing
protein CRADD (Caspase and RIP adaptator with DEATH domain) (RIP
associated protein with a DEATH
domain).//:trembl|BC017042|BC017042_1 product: "CASP2 and RIPK1
domain containing adaptor with death domain"; Homo sapiens, CASP2
and RIPK1 domain containing adaptor with death domain, clone
MGC:9163 IMAGE:3849848, mRNA, complete cds.
//:trembl|U79115|HSU79115_1 gene: "RAIDD"; product: "death adaptor
molecule RAIDD"; Human death adaptor molecule RAIDD (RAIDD) mRNA,
complete cds. //:trembl|U84388|HSU84388_1 product: "death domain
containing protein CRADD"; Human death domain containing protein
CRADD mRNA, complete cds. //:gp|U79115|1785557 death adaptor
molecule RAIDD [Homo sapiens]//:gp|U84388|1809140 death domain
containing protein CRADD [Homo sapiens]//:gp|BC017042|16877581
CASP2 and RIPK1 domain containing adaptor with death domain [Homo
sapiens]
Length = 199
0 40 80 120 160
| | | | | |199
swissnew|P78560|CRAD_ | __________________________________________________
Local hits (HSPs) | ___________________
Score = 109 (43.4 bits), Expect = 6.0e-06, P = 6.0e-06
Identities = 24/73 (32%), Positives = 46/73 (63%)
Query: 5 QETLKKNRVVLAKQLLLSEL-LEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRG 63
++ L+ R+ L ++L+ L L++L ++ I+T + I A+ + + LL++LP RG
Sbjct: 6 KQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDILPSRG 65
Query: 64 PQAFDAFCEALRE 76
P+AFD F ++L+E
Sbjct: 66 PKAFDTFLDSLQE 78
^ = sptrembl|Q9IB63|Q9IB63 Caspase-9.//:trembl|AB038172|AB038172_1 gene:
"xCaspase-9"; product: "caspase-9"; Xenopus laevis mRNA for
caspase-9, complete cds. //:gp|AB038172|7619908 caspase-9 [Xenopus
laevis]
Length = 399
0 80 160 240 320
| | | | | |399
sptrembl|Q9IB63|Q9IB6 | __________________________________________________
Local hits (HSPs) | ___________
Score = 114 (45.2 bits), Expect = 8.5e-06, P = 8.5e-06
Identities = 31/82 (37%), Positives = 46/82 (56%)
Query: 5 QETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGP 64
++ L++NRV L + L + EL + L+E+ + + +M E IQ + Q +LL L RG
Sbjct: 6 RDILRRNRVRLVQSLQVKELWDLLVERGVFSNDMIEEIQREGTRRDQARKLLVELETRGS 65
Query: 65 QAFDAFCEALRETKQGHLEDML 86
QAF F L+ET Q L D L
Sbjct: 66 QAFPLFLLCLKETAQHDLADFL 87
^ = pironly|T20038|T20038 hypothetical protein C48D1.2 - Caenorhabditis elegans
Length = 495
0 100 200 300 400
| | | | | |495
pironly|T20038|T20038 | __________________________________________________
Local hits (HSPs) | ________
Score = 99 (39.9 bits), Expect = 0.00049, P = 0.00049
Identities = 23/79 (29%), Positives = 45/79 (56%)
Query: 8 LKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAF 67
L++N ++ + L + E+LE L+ K ++ + ++I + + E++ + +RG AF
Sbjct: 9 LERNIMMFSSHLKVDEILEVLIAKQVLNSDNGDMINSCGTVREKRREIVKAVQRRGDVAF 68
Query: 68 DAFCEALRETKQGHLEDML 86
DAF +ALR T L ++L
Sbjct: 69 DAFYDALRSTGHEGLAEVL 87
^ = swissnew|P45436|CED3_CAEVU Cell death protein 3 precursor (EC
3.4.22.-).//:swiss|P45436|CED3_CAEVU Cell death protein 3 precursor
(EC 3.4.22.-).
Length = 496
0 100 200 300 400
| | | | | |496
swissnew|P45436|CED3_ | __________________________________________________
Local hits (HSPs) | _______
Score = 99 (39.9 bits), Expect = 0.00049, P = 0.00049
Identities = 22/74 (29%), Positives = 44/74 (59%)
Query: 8 LKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAF 67
L++N +V + +L ++L+ L+ KD++ + ++I + + E + + +RG +AF
Sbjct: 10 LERNILVFSNKLQSEQILDVLIAKDVLNSDNGDMINSCRTERDKRKEQVKAVQRRGDEAF 69
Query: 68 DAFCEALRETKQGH 81
D F +ALR+T GH
Sbjct: 70 DRFYDALRDT--GH 81
^ = swissnew|P42573|CED3_CAEEL Cell death protein 3 precursor (EC
3.4.22.-).//:swiss|P42573|CED3_CAEEL Cell death protein 3 precursor
(EC 3.4.22.-).//:tremblnew|Z81049|CEC48D1_2 gene: "ced-3"; product:
"C. elegans CED-3 protein (corresponding sequence C48D1.2)";
Caenorhabditis elegans cosmid C48D1 //:trembl|AF210702|AF210702_1
gene: "ced-3"; product: "caspase CED-3"; Caenorhabditis elegans
caspase CED-3 (ced-3) mRNA, complete cds.
//:trembl|Z81049|CEC48D1_3 gene: "ced-3"; product: "C. elegans
ced-3 protein (corresponding sequence C48D1.2)"; Caenorhabditis
elegans cosmid C48D1 //:trembl|L29052|CECED3A_1 gene: "ced-3";
product: "cell death protein"; Caenorhabditis elegans cell death
protein (ced-3) gene, complete cds. //:pironly|A49429|A49429
interleukin-1 beta-converting enzyme homolog CED-3 - Caenorhabditis
elegans//:gp|L29052|6503233 cell death protein [Caenorhabditis
elegans]//:gp|AF210702|11967321 caspase CED-3 [Caenorhabditis
elegans]//:gp|Z81049|15718157 C. elegans CED-3 protein
(corresponding sequence C48D1.2) [Caenorhabditis
elegans]//:worm|CE29088|C48D1.2 locus:ced-3 Caspase recruitment
domain, ICE-like protease (caspase) p20 domain., ICE-like protease
(caspase) p10 domain. status:Confirmed SW:P42573
protein_id:CAB61001.2
Length = 503
0 100 200 300 400 500
| | | | | |503
swissnew|P42573|CED3_ | __________________________________________________
Local hits (HSPs) | _______
Score = 99 (39.9 bits), Expect = 0.00050, P = 0.00050
Identities = 23/79 (29%), Positives = 45/79 (56%)
Query: 8 LKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAF 67
L++N ++ + L + E+LE L+ K ++ + ++I + + E++ + +RG AF
Sbjct: 10 LERNIMMFSSHLKVDEILEVLIAKQVLNSDNGDMINSCGTVREKRREIVKAVQRRGDVAF 69
Query: 68 DAFCEALRETKQGHLEDML 86
DAF +ALR T L ++L
Sbjct: 70 DAFYDALRSTGHEGLAEVL 88
^ = trembl|AX082238|AX082238_1 unnamed ORF; Sequence 40 from Patent WO0100826.
//:gp|AX082238|13171002 unnamed protein product [Homo sapiens]
Length = 164
0 40 80 120 160
| | | | | |164
trembl|AX082238|AX082 | __________________________________________________
Local hits (HSPs) | _________________________
Score = 77 (32.2 bits), Expect = 0.017, P = 0.017
Identities = 21/84 (25%), Positives = 45/84 (53%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSE-LLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLL 59
HPH Q LK NR +L + ++ L+++LL+ D + E E++ A + ++L+L+
Sbjct: 17 HPHIQ-LLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLV 75
Query: 60 PKRGPQAFDAFCEALRETKQGHLE 83
+G + + F L++ +++
Sbjct: 76 QSKGEEVSEFFLYLLQQLADAYVD 99
^ = swissnew|O95999|BCLA_HUMAN B cell lymphoma/leukemia 10 (B-cell CLL/lymphoma
10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator)
(CIPER) (CARD- containing molecule enhancing NFkappaB) (Cellular
homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter
molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic
protein) (hCLAP).//:swiss|O95999|BCLA_HUMAN B cell
lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED-
3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (CARD-
containing molecule enhancing NFkappaB) (Cellular homolog of
vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10)
(mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein)
(hCLAP).//:trembl|AF057700|AF057700_1 gene: "CIPER"; product:
"CIPER protein"; Homo sapiens CIPER protein (CIPER) mRNA, complete
cds. //:trembl|AF082283|AF082283_1 gene: "BCL10"; product:
"CARD-containing apoptotic signaling protein"; Homo sapiens
CARD-containing apoptotic signaling protein (BCL10) mRNA, complete
cds. //:trembl|AF097732|AF097732_1 gene: "BCL10"; product: "caspase
recruitment domain-containing protein"; Homo sapiens caspase
recruitment domain-containing protein (BCL10) gene, complete cds.
//:trembl|AF100338|AF100338_1 product: "CARD containing molecule
enhancing NF-kB"; Homo sapiens CARD containing molecule enhancing
NF-kB mRNA, complete cds. //:trembl|AF105066|AF105066_1 product:
"caspase-recruiting domain-containing protein c-E10"; Homo sapiens
caspase-recruiting domain-containing protein c-E10 mRNA, complete
cds. //:trembl|AF127386|AF127386_1 gene: "ME10"; product:
"CARD-containing proapoptotic protein ME10"; Homo sapiens
CARD-containing proapoptotic protein ME10 (ME10) mRNA, complete
cds. //:trembl|AF134395|AF134395_1 gene: "CLAP"; product:
"CARD-like apoptotic protein"; Homo sapiens CARD-like apoptotic
protein (CLAP) mRNA, complete cds. //:trembl|AJ006288|HSA6288_1
gene: "bcl-10"; Homo sapiens mRNA for bcl-10 protein
//:gp|AF097732|4583048 caspase recruitment domain-containing
protein [Homo sapiens]//:gp|AF082283|4092067 CARD-containing
apoptotic signaling protein [Homo sapiens]//:gp|AF127386|4894742
CARD-containing proapoptotic protein ME10 [Homo
sapiens]//:gp|AF134395|5070372 CARD-like apoptotic protein [Homo
sapiens]//:gp|AF057700|4321706 CIPER protein [Homo
sapiens]//:gp|AF100338|4323571 CARD containing molecule enhancing
NF-kB [Homo sapiens]//:gp|AF105066|6318435 caspase-recruiting
domain-containing protein c-E10 [Homo
sapiens]//:gp|AJ006288|4049460 bcl-10 [Homo sapiens]
Length = 233
0 50 100 150 200
| | | | | |233
swissnew|O95999|BCLA_ | __________________________________________________
Local hits (HSPs) | _______________
Score = 80 (33.2 bits), Expect = 0.017, P = 0.017
Identities = 20/74 (27%), Positives = 38/74 (51%)
Query: 5 QETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGP 64
++ L+ RV L ++++ +HL K I++ E E I + S + +LL+ L + P
Sbjct: 18 KDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYL-QENP 76
Query: 65 QAFDAFCEALRETK 78
+ D E++R K
Sbjct: 77 KGLDTLVESIRREK 90
^ = swissnew|Q9Z0H7|BCLA_MOUSE B cell lymphoma/leukemia 10 (B-cell CLL/lymphoma
10) (Bcl-10) (CED- 3/ICH-1 prodomain homologous E10-like regulator)
(mCIPER) (CARD- containing molecule enhancing NFkappaB) (Cellular
homolog of vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter
molecule E10) (mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic
protein) (mCLAP).//:swiss|Q9Z0H7|BCLA_MOUSE B cell
lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CED-
3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (CARD-
containing molecule enhancing NFkappaB) (Cellular homolog of
vCARMEN) (cCARMEN) (Mammalian CARD-containing adapter molecule E10)
(mE10) (Cellular-E10) (c-E10) (CARD-like apoptotic protein)
(mCLAP).//:sptremblnew|BAC36168|BAC36168 11 days embryo whole body
cDNA, RIKEN full-length enriched library, clone:2700094G04
product:B-cell leukemia/lymphoma 10, full insert
sequence.//:tremblnew|AK076082|AK076082_1 Mus musculus 11 days
embryo whole body cDNA, RIKEN full-length enriched library,
clone:2700094G04 product:B-cell leukemia/lymphoma 10, full insert
sequence. //:trembl|AF057701|AF057701_1 gene: "Ciper"; product:
"CIPER protein"; Mus musculus CIPER protein (Ciper) mRNA, complete
cds. //:trembl|AF100339|AF100339_1 product: "CARD containing
molecule enhancing NF-kB"; Mus musculus CARD containing molecule
enhancing NF-kB mRNA, complete cds. //:trembl|AF127387|AF127387_1
gene: "Me10"; product: "CARD-containing proapoptotic protein ME10";
Mus musculus CARD-containing proapoptotic protein ME10 (Me10) mRNA,
complete cds. //:trembl|AF134396|AF134396_1 gene: "Clap"; product:
"CARD-like apoptotic protein"; Mus musculus CARD-like apoptotic
protein (Clap) mRNA, complete cds. //:trembl|BC024379|BC024379_1
product: "B-cell leukemia/lymphoma 10"; Mus musculus, B-cell
leukemia/lymphoma 10, clone MGC:36096 IMAGE:4976147, mRNA, complete
cds. //:trembl|AJ006289|MMU6289_1 gene: "bcl-10"; Mus musculus
mRNA for bcl-10 protein //:gp|AF127387|4894744 CARD-containing
proapoptotic protein ME10 [Mus musculus]//:gp|AF134396|5070374
CARD-like apoptotic protein [Mus musculus]//:gp|AF057701|4321708
CIPER protein [Mus musculus]//:gp|AF100339|4323573 CARD containing
molecule enhancing NF-kB [Mus musculus]//:gp|AK076082|26345038
unnamed protein product [Mus musculus]//:gp|AJ006289|4049472 bcl-10
[Mus musculus]//:gp|BC024379|19353889 B-cell leukemia/lymphoma 10
[Mus musculus]
Length = 233
0 50 100 150 200
| | | | | |233
swissnew|Q9Z0H7|BCLA_ | __________________________________________________
Local hits (HSPs) | _______________
Score = 80 (33.2 bits), Expect = 0.017, P = 0.017
Identities = 20/74 (27%), Positives = 38/74 (51%)
Query: 5 QETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGP 64
++ L+ RV L ++++ +HL K I++ E E I + S + +LL+ L + P
Sbjct: 18 KDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYL-QENP 76
Query: 65 QAFDAFCEALRETK 78
+ D E++R K
Sbjct: 77 RGLDTLVESIRREK 90
^ = swissnew|Q62210|BIR3_MOUSE Baculoviral IAP repeat-containing protein 3
(Inhibitor of apoptosis protein 2) (MIAP2)
(MIAP-2).//:swiss|Q62210|BIR3_MOUSE Baculoviral IAP
repeat-containing protein 3 (Inhibitor of apoptosis protein 2)
(MIAP2) (MIAP-2).//:trembl|L49433|MMSCPB_1 product: "TNFR2-TRAF
signalling complex protein"; Mus musculus TNFR2-TRAF signalling
complex protein mRNA, complete cds. //:gp|L49433|1161128 TNFR2-TRAF
signalling complex protein [Mus musculus]
Length = 612
0 130 260 390 520
| | | | | |612
swissnew|Q62210|BIR3_ | __________________________________________________
Local hits (HSPs) | ______
Score = 85 (35.0 bits), Expect = 0.021, P = 0.020
Identities = 23/81 (28%), Positives = 46/81 (56%)
Query: 8 LKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
++KNR+ L +QL + +L++LLE +IT + ++I+ K Q EL++ + +G A
Sbjct: 455 IRKNRMALFQQLTHVLPILDNLLEASVITKQEHDIIRQKTQIPLQARELIDTVLVKGNAA 514
Query: 67 FDAFCEALRETKQGHLEDMLL 87
+ F +L+E E++ +
Sbjct: 515 ANIFKNSLKEIDSTLYENLFV 535
^ = sptrembl|Q9QZC6|Q9QZC6 Inhibitor of apoptosis protein
2.//:trembl|AF190020|AF190020_1 product: "inhibitor of apoptosis
protein 2"; Rattus norvegicus inhibitor of apoptosis protein 2
mRNA, complete cds. //:gp|AF190020|6164925 inhibitor of apoptosis
protein 2 [Rattus norvegicus]
Length = 589
0 120 240 360 480
| | | | | |589
sptrembl|Q9QZC6|Q9QZC | __________________________________________________
Local hits (HSPs) | _____
Score = 84 (34.6 bits), Expect = 0.025, P = 0.025
Identities = 22/70 (31%), Positives = 40/70 (57%)
Query: 8 LKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
++KNR+ L +QL + +L+ LLE ++T E ++I+ K Q EL++ + +G A
Sbjct: 432 IRKNRMALFQQLTCVIPILDDLLEASVLTKEEHDIIRQKTQIPLQARELIDTILVKGNAA 491
Query: 67 FDAFCEALRE 76
F +L+E
Sbjct: 492 ASVFKNSLKE 501
^ = sptrembl|Q66677|Q66677 ORF E10.//:trembl|U20824|EHU20824_78 Equine
herpesvirus 2, complete genome. //:pironly|S55671|S55671
hypothetical protein E10 - equine herpesvirus 2//:gp|U20824|695250
ORF E10 [Equine herpesvirus 2]
Length = 210
0 50 100 150 200
| | | | | |210
sptrembl|Q66677|Q6667 | __________________________________________________
Local hits (HSPs) | __________________
Score = 76 (31.8 bits), Expect = 0.039, P = 0.039
Identities = 24/80 (30%), Positives = 42/80 (52%)
Query: 8 LKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAF 67
L++ RV+L L + L+HL K I++ E E + ++ S S+ L+++ P+ F
Sbjct: 29 LEELRVLLVSHLKSHKHLDHLRAKKILSREDAEEVSSRATSRSRAGLLVDMCQDH-PRGF 87
Query: 68 DAFCEALR-ETKQGHLEDML 86
E+ + E Q HL D+L
Sbjct: 88 QCLKESCKNEVGQEHLVDLL 107
^ = trembl|AX082236|AX082236_1 unnamed ORF; Sequence 38 from Patent WO0100826.
//:gp|AX082236|13171000 unnamed protein product [Homo sapiens]
Length = 249
0 50 100 150 200
| | | | | |249
trembl|AX082236|AX082 | __________________________________________________
Local hits (HSPs) | ________________
Score = 77 (32.2 bits), Expect = 0.042, P = 0.041
Identities = 21/84 (25%), Positives = 45/84 (53%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSE-LLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLL 59
HPH Q LK NR +L + ++ L+++LL+ D + E E++ A + ++L+L+
Sbjct: 17 HPHIQ-LLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLV 75
Query: 60 PKRGPQAFDAFCEALRETKQGHLE 83
+G + + F L++ +++
Sbjct: 76 QSKGEEVSEFFLYLLQQLADAYVD 99
^ = trembl|AX098236|AX098236_1 unnamed ORF; Sequence 11 from Patent WO0118208.
//:gp|AX098236|13515372 unnamed protein product [Homo sapiens]
Length = 308
0 70 140 210 280
| | | | | |308
trembl|AX098236|AX098 | __________________________________________________
Local hits (HSPs) | _____________
Score = 78 (32.5 bits), Expect = 0.046, P = 0.045
Identities = 24/84 (28%), Positives = 43/84 (51%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKV--GSFSQNVELLNL 58
H + + L + L +LL+ ++L+ +E++++T+E R I A G+ S ELL
Sbjct: 161 HDEYLQLLNLLQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKR 220
Query: 59 LPKRGPQAFDAFCEALRETKQGHL 82
+ ++ F AF LR+T L
Sbjct: 221 IVQK-ENWFSAFLNVLRQTGNNEL 243
^ = sptrembl|Q9W199|Q9W199 CG4326 protein
(RE28524p).//:tremblnew|AE003463|AE003463_20 gene: "mRpS17";
product: "CG4326-PA"; Drosophila melanogaster chromosome 2R,
section 71 of 74 of the complete sequence.
//:trembl|AE003463|AE003463_20 gene: "mRpS17"; product:
"CG4326-PA"; Drosophila melanogaster chromosome 2R, section 71 of
74 of the complete sequence. //:trembl|AY084147|AY084147_1 product:
"RE28524p"; Drosophila melanogaster RE28524 full insert cDNA.
//:gp|AY084147|19527541 RE28524p [Drosophila
melanogaster]//:gp|AE003463|7291756 CG4326-PA [Drosophila
melanogaster]//:gpnew|AE003463|7291756 CG4326-PA [Drosophila
melanogaster]
Length = 155
0 40 80 120
| | | | |155
sptrembl|Q9W199|Q9W19 | __________________________________________________
Local hits (HSPs) | ______________________
Score = 71 (30.1 bits), Expect = 0.073, P = 0.070
Identities = 21/70 (30%), Positives = 40/70 (57%)
Query: 5 QETLKKNRVVLAKQL--LLSELLEHLLEKDIITL-EMRELIQAK---VGSFSQNVELLNL 58
Q+ K VVL ++L L+ L+ H +EK + L ++ + + K VG++ +++E+ N
Sbjct: 50 QKVCKTGDVVLIRELPERLTRLITHNVEKVVYPLGDITDPLTGKKVVVGNYREDIEMANQ 109
Query: 59 LPKRGPQAFD 68
L + +AFD
Sbjct: 110 LFGKSEKAFD 119
^ = sptrembl|Q9YJN5|Q9YJN5 Hypothetical 32.6 kDa
protein.//:trembl|AF100340|AF100340_1 gene: "E10"; product:
"v-CARMEN"; Equine herpesvirus 2 v-CARMEN (E10) mRNA, complete
cds. //:trembl|AF134394|AF134394_1 gene: "CLAP"; product:
"CARD-like apoptotic protein"; Equine herpesvirus 2 CARD-like
apoptotic protein (CLAP) gene, complete cds.
//:trembl|AJ006410|EHE6410_1 product: "hypothetical protein";
Equine herpesvirus 2 ORF E10 //:gp|AF134394|5070370 CARD-like
apoptotic protein [Equine herpesvirus 2]//:gp|AF100340|4323575
v-CARMEN [Equine herpesvirus 2]//:gp|AJ006410|4049421 hypothetical
protein [Equine herpesvirus 2]
Length = 311
0 70 140 210 280
| | | | | |311
sptrembl|Q9YJN5|Q9YJN | __________________________________________________
Local hits (HSPs) | ____________
Score = 76 (31.8 bits), Expect = 0.077, P = 0.074
Identities = 24/80 (30%), Positives = 42/80 (52%)
Query: 8 LKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAF 67
L++ RV+L L + L+HL K I++ E E + ++ S S+ L+++ P+ F
Sbjct: 29 LEELRVLLVSHLKSHKHLDHLRAKKILSREDAEEVSSRATSRSRAGLLVDMCQDH-PRGF 87
Query: 68 DAFCEALR-ETKQGHLEDML 86
E+ + E Q HL D+L
Sbjct: 88 QCLKESCKNEVGQEHLVDLL 107
^ = swissnew|Q8SL86|RPOA_EUGVI DNA-directed RNA polymerase alpha chain (EC
2.7.7.6) (PEP) (Plastid- encoded RNA polymerase alpha subunit) (RNA
polymerase alpha subunit).//:swiss|Q8SL86|RPOA_EUGVI DNA-directed
RNA polymerase alpha chain (EC 2.7.7.6) (PEP) (Plastid- encoded RNA
polymerase alpha subunit) (RNA polymerase alpha
subunit).//:trembl|AY047487|AY047487_2 gene: "rpoA"; product: "RNA
polymerase alpha subunit"; Euglena viridis ycf9 (ycf9) gene,
partial cds; RNA polymerase alpha subunit gene, complete cds; and
tRNA-Ser (trnS) gene, complete sequence; chloroplast genes for
chloroplast products. //:gp|AY047487|19168446 RNA polymerase alpha
subunit [Euglena viridis]
Length = 214
0 50 100 150 200
| | | | | |214
swissnew|Q8SL86|RPOA_ | __________________________________________________
Local hits (HSPs) | __________________
Score = 72 (30.4 bits), Expect = 0.11, P = 0.11
Identities = 17/79 (21%), Positives = 42/79 (53%)
Query: 3 HHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAK--VGSFSQNVELLNLLP 60
++ +T ++ ++L+K + L + +H+ + L+M+ +++AK +GSF V+ +N +
Sbjct: 115 YYPKTYSQDDIILSKNIKLIKKNQHIFSLSSLKLKMKFILEAKKGIGSFFTPVKRVNYII 174
Query: 61 KRGPQAFDAFCEALRETKQ 79
+ +F L K+
Sbjct: 175 EENKLSFSRVVLELETDKR 193
^ = swissnew|Q9Y2G2|CAR8_HUMAN Caspase recruitment domain protein 8 (Apoptotic
protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappaB activating
ligand) (CARDINAL) (TUCAN).//:swiss|Q9Y2G2|CAR8_HUMAN Caspase
recruitment domain protein 8 (Apoptotic protein NDPP1) (DACAR)
(CARD-inhibitor of NF-kappaB activating ligand) (CARDINAL)
(TUCAN).//:trembl|AB023172|AB023172_1 gene: "KIAA0955"; product:
"KIAA0955 protein"; Homo sapiens mRNA for KIAA0955 protein,
complete cds. //:trembl|AF322184|AF322184_1 gene: "CARD8"; product:
"caspase recruitment domain protein 8"; Homo sapiens caspase
recruitment domain protein 8 (CARD8) mRNA, complete cds.
//:trembl|AF331519|AF331519_1 gene: "DNPP+"; product: "apoptotic
protein NDPP1"; Homo sapiens apoptotic protein NDPP1 (DNPP+) mRNA,
complete cds. //:trembl|AY026322|AY026322_1 product:
"CARD-containing protein DACAR"; Homo sapiens CARD-containing
protein DACAR mRNA, complete cds. //:trembl|AX089767|AX089767_1
unnamed ORF; Sequence 7 from Patent WO0116170.
//:gp|AB023172|4589554 KIAA0955 protein [Homo
sapiens]//:gp|AX089767|13443940 unnamed protein product [Homo
sapiens]//:gp|AF331519|12658408 apoptotic protein NDPP1 [Homo
sapiens]//:gp|AY026322|13027707 CARD-containing protein DACAR [Homo
sapiens]//:gp|AF322184|12247742 caspase recruitment domain protein
8 [Homo sapiens]
Length = 431
0 90 180 270 360
| | | | | |431
swissnew|Q9Y2G2|CAR8_ | __________________________________________________
Local hits (HSPs) | ________
Score = 75 (31.5 bits), Expect = 0.16, P = 0.14
Identities = 19/70 (27%), Positives = 40/70 (57%)
Query: 8 LKKN-RVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
+K+N R + A+ L +L+ L + +++T +EL++ + S+N LL+++ K+G A
Sbjct: 348 VKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLA 407
Query: 67 FDAFCEALRE 76
D ++ E
Sbjct: 408 LDVLFRSISE 417
^ = sptremblnew|AAO24632|AAO24632 Inhibitor of apoptosis
protein-1.//:tremblnew|AY184377|AY184377_1 gene: "cIAP-1"; product:
"inhibitor of apoptosis protein-1"; Ictalurus punctatus inhibitor
of apoptosis protein-1 (cIAP-1) mRNA, complete cds.
//:gp|AY184377|27903492 inhibitor of apoptosis protein-1 [Ictalurus
punctatus]
Length = 616
0 130 260 390 520
| | | | | |616
sptremblnew|AAO24632| | __________________________________________________
Local hits (HSPs) | ______
Score = 76 (31.8 bits), Expect = 0.19, P = 0.17
Identities = 20/83 (24%), Positives = 45/83 (54%)
Query: 8 LKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
LKK+ L ++L + L++HLLE+++I+ + + I+ Q +L++L+ +G A
Sbjct: 459 LKKHHAALTQRLKSVQSLMDHLLEENVISQKEYDTIRNCTSVKQQTGQLIDLVLSKGNAA 518
Query: 67 FDAFCEALRETKQGHLEDMLLTT 89
+ F +++ L +++ T
Sbjct: 519 AEVFRNWIKKNDVYLLRELMAQT 541
^ = swissnew|Q13490|BIR3_HUMAN Baculoviral IAP repeat-containing protein 3
(Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1)
(TNFR2-TRAF signaling complex protein 2) (IAP homolog
B).//:swiss|Q13490|BIR3_HUMAN Baculoviral IAP repeat-containing
protein 3 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2)
(C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog
B).//:sptremblnew|AAH28578|AAH28578 Baculoviral IAP
repeat-containing 2.//:trembl|BC016174|BC016174_1 product:
"baculoviral IAP repeat-containing 2"; Homo sapiens, baculoviral
IAP repeat-containing 2, clone MGC:17185 IMAGE:3908352, mRNA,
complete cds. //:trembl|BC028578|BC028578_1 product: "baculoviral
IAP repeat-containing 2"; Homo sapiens, baculoviral IAP
repeat-containing 2, clone MGC:26517 IMAGE:4831062, mRNA, complete
cds. //:trembl|U37547|HS375471_1 gene: "MIHB"; product: "MIHB";
Human IAP homolog B (MIHB) mRNA, complete cds.
//:trembl|L49431|HSSCPA_1 product: "TNFR2-TRAF signalling complex
protein"; Homo sapiens TNFR2-TRAF signalling complex protein mRNA,
complete cds. //:gp|L49431|1160973 TNFR2-TRAF signalling complex
protein [Homo sapiens]//:gp|U37547|1145293 MIHB [Homo
sapiens]//:gp|BC016174|16740585 baculoviral IAP repeat-containing 2
[Homo sapiens]//:gp|BC028578|22382084 baculoviral IAP
repeat-containing 2 [Homo sapiens]
Length = 618
0 130 260 390 520
| | | | | |618
swissnew|Q13490|BIR3_ | __________________________________________________
Local hits (HSPs) | _____
Score = 76 (31.8 bits), Expect = 0.19, P = 0.17
Identities = 20/70 (28%), Positives = 41/70 (58%)
Query: 8 LKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
++KNR+ L +QL + +L++LL+ ++I + ++I+ K Q EL++ + +G A
Sbjct: 461 IRKNRMALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAA 520
Query: 67 FDAFCEALRE 76
+ F L+E
Sbjct: 521 ANIFKNCLKE 530
^ = sptrembl|Q8UWD2|Q8UWD2 Iap1.//:trembl|AF442500|AF442500_1 gene: "iap1";
product: "Iap1"; Danio rerio Iap1 (iap1) mRNA, complete cds.
//:gp|AF442500|17017468 Iap1 [Danio rerio]
Length = 628
0 130 260 390 520
| | | | | |628
sptrembl|Q8UWD2|Q8UWD | __________________________________________________
Local hits (HSPs) | ______
Score = 76 (31.8 bits), Expect = 0.19, P = 0.18
Identities = 20/83 (24%), Positives = 46/83 (55%)
Query: 8 LKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
LKK+ L+++L + L++HLLE+++I+ + + I+ Q +L++L+ +G A
Sbjct: 471 LKKHHAALSQRLKSVQSLMDHLLEENVISQKEYDSIRNCTSVKQQTGQLIDLVLSKGNAA 530
Query: 67 FDAFCEALRETKQGHLEDMLLTT 89
+ F +++ L +++ T
Sbjct: 531 AEVFRNWIKKNDVYLLRELMAQT 553
^ = sptrembl|Q9BYX4|Q9BYX4 RNA helicase-DEAD box protein
RH116.//:trembl|AY017378|AY017378_1 product: "RNA helicase-DEAD box
protein RH116"; Homo sapiens RNA helicase-DEAD box protein RH116
mRNA, complete cds. //:trembl|AX300832|AX300832_1 unnamed ORF;
Sequence 1 from Patent WO0185955. //:gp|AX300832|17382111 unnamed
protein product [Homo sapiens]//:gp|AY017378|12621066 RNA
helicase-DEAD box protein RH116 [Homo sapiens]
Length = 1025
0 210 420 630 840
| | | | | |1025
sptrembl|Q9BYX4|Q9BYX | __________________________________________________
Local hits (HSPs) | ____
Score = 78 (32.5 bits), Expect = 0.21, P = 0.19
Identities = 24/84 (28%), Positives = 43/84 (51%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKV--GSFSQNVELLNL 58
H + + L + L +LL+ ++L+ +E++++T+E R I A G+ S ELL
Sbjct: 111 HDEYLQLLNLLQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKR 170
Query: 59 LPKRGPQAFDAFCEALRETKQGHL 82
+ ++ F AF LR+T L
Sbjct: 171 IVQK-ENWFSAFLNVLRQTGNNEL 193
^ = swissnew|Q9Y239|CAR4_HUMAN Caspase recruitment domain protein 4 (Nod1
protein).//:swiss|Q9Y239|CAR4_HUMAN Caspase recruitment domain
protein 4 (Nod1 protein).//:trembl|AF113925|AF113925_1 product:
"Nod1"; Homo sapiens Nod1 mRNA, complete cds.
//:trembl|AF126484|AF126484_1 product: "CARD4"; Homo sapiens CARD4
mRNA, complete cds. //:trembl|AF149774|AF149774_1 gene: "NOD1";
product: "NOD1 protein"; Homo sapiens NOD1 protein (NOD1) gene,
exons 4 through 14 and complete cds. //:trembl|AX082205|AX082205_1
unnamed ORF; Sequence 7 from Patent WO0100826.
//:gp|AF126484|4760400 CARD4 [Homo sapiens]//:gp|AF113925|4731026
Nod1 [Homo sapiens]//:gp|AF149774|5478674 NOD1 protein [Homo
sapiens]//:gp|AX082205|13170990 unnamed protein product [Homo
sapiens]
Length = 953
0 190 380 570 760 950
| | | | | |953
swissnew|Q9Y239|CAR4_ | __________________________________________________
Local hits (HSPs) | ____
Score = 77 (32.2 bits), Expect = 0.25, P = 0.22
Identities = 21/84 (25%), Positives = 45/84 (53%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSE-LLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLL 59
HPH Q LK NR +L + ++ L+++LL+ D + E E++ A + ++L+L+
Sbjct: 17 HPHIQ-LLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLV 75
Query: 60 PKRGPQAFDAFCEALRETKQGHLE 83
+G + + F L++ +++
Sbjct: 76 QSKGEEVSEFFLYLLQQLADAYVD 99
^ = swiss|O62640|PIAP_PIG Putative inhibitor of
apoptosis.//:trembl|U79142|U79142_1 gene: "PIAP"; product:
"putative inhibitor of apoptosis"; Sus scrofa putative inhibitor
of apoptosis (PIAP) mRNA, complete cds. //:pironly|JC5964|JC5964
apoptosis inhibitor - pig//:gp|U79142|2957175 putative inhibitor of
apoptosis [Sus scrofa]
Length = 358
0 80 160 240 320
| | | | | |358
swiss|O62640|PIAP_PIG | __________________________________________________
Local hits (HSPs) | __________
Score = 71 (30.1 bits), Expect = 0.33, P = 0.28
Identities = 20/76 (26%), Positives = 42/76 (55%)
Query: 2 PHHQETLKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
P+ ++KNR+ L + L + +L+ LL +I+ + ++I+ K + Q EL++++
Sbjct: 195 PNDLSLIRKNRMALFQHLTCVLPILDSLLIARVISEQEHDVIKQKTQTSLQARELIDIIL 254
Query: 61 KRGPQAFDAFCEALRE 76
+G A F +L+E
Sbjct: 255 VKGNYAATIFKNSLQE 270
^ = swissnew|Q9I9H8|APAF_BRARE Apoptotic protease activating factor 1
(Apaf-1).//:swiss|Q9I9H8|APAF_BRARE Apoptotic protease activating
factor 1 (Apaf-1).//:trembl|AF251502|AF251502_1 gene: "apaf1";
product: "Apaf-1"; Danio rerio Apaf-1 (apaf1) mRNA, complete cds.
//:gp|AF251502|7677507 Apaf-1 [Danio rerio]
Length = 1261
0 260 520 780 1040
| | | | | |1261
swissnew|Q9I9H8|APAF_ | __________________________________________________
Local hits (HSPs) | ____
Score = 77 (32.2 bits), Expect = 0.34, P = 0.29
Identities = 19/79 (24%), Positives = 39/79 (49%)
Query: 8 LKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAF 67
L +++ L + + S L++H++ ++T + + +K Q V LL L ++ +A+
Sbjct: 9 LLRSKATLEQDIKASYLMDHMISDGVLTNDEEAKVLSKATRKEQAVALLETLLRKDNRAY 68
Query: 68 DAFCEALRETKQGHLEDML 86
+F AL G L +L
Sbjct: 69 ISFYNALIRESYGDLASLL 87
^ = swissnew|Q08346|PRIM_HAEIN DNA primase (EC
2.7.7.-).//:swiss|Q08346|PRIM_HAEIN DNA primase (EC
2.7.7.-).//:trembl|U32735|HI32735_7 gene: "HI0532"; product: "DNA
primase (dnaG)"; Haemophilus influenzae Rd section 50 of 163 of
the complete genome. //:pironly|A64075|A64075 DNA primase (EC
2.7.7.-) - Haemophilus influenzae (strain Rd
KW20)//:gp|U32735|1573516 DNA primase (dnaG) [Haemophilus
influenzae Rd]
Length = 593
0 120 240 360 480
| | | | | |593
swissnew|Q08346|PRIM_ | __________________________________________________
Local hits (HSPs) | ____
Score = 72 (30.4 bits), Expect = 0.49, P = 0.39
Identities = 17/50 (34%), Positives = 30/50 (60%)
Query: 17 KQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
K + L+ L H + +++ L +R ++ K+G F Q +L NL+PK+ QA
Sbjct: 391 KLVALAAPLIHQIPGEMLRLSLRNMLAQKLGIFDQT-QLENLIPKKLEQA 439
^ = swissnew|Q980E8|GCH1_SULSO GTP cyclohydrolase I (EC 3.5.4.16)
(GTP-CH-I).//:swiss|Q980E8|GCH1_SULSO GTP cyclohydrolase I (EC
3.5.4.16) (GTP-CH-I).//:trembl|AE006669|AE006669_16 gene: "folE";
product: "GTP cyclohydrolase I (folE)"; Sulfolobus solfataricus
section 28 of 272 of the complete genome. //:pironly|G90179|G90179
GTP cyclohydrolase I (folE) [imported] - Sulfolobus
solfataricus//:gp|AE006669|13813508 GTP cyclohydrolase I (folE)
[Sulfolobus solfataricus]
Length = 208
0 50 100 150 200
| | | | | |208
swissnew|Q980E8|GCH1_ | __________________________________________________
Local hits (HSPs) | _____________
Score = 66 (28.3 bits), Expect = 0.50, P = 0.40
Identities = 17/59 (28%), Positives = 30/59 (50%)
Query: 6 ETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQ--AKVGSFSQNVELLNLLPKR 62
E +KN++VL K + S L EH + I + + ++ KV FS+ + ++N R
Sbjct: 70 EVYEKNQIVLIKDVNFSSLCEHHMLPIIGKIHVAYIVSNSGKVAGFSKIIRIVNYYSSR 128
^ = sptrembl|Q8KQ40|Q8KQ40 Putative transcription
regulator.//:trembl|AY112701|AY112701_2 product: "putative
transcription regulator"; Thiobacillus denitrificans putative
integral membrane protein gene, partial cds; and putative
transcription regulator, sulfide:quinone oxidoreductase (sqr), and
putative high molecular mass cytochrome c precursor, genes,
complete cds. //:gp|AY112701|21464539 putative transcription
regulator [Thiobacillus denitrificans]
Length = 302
0 60 120 180 240 300
| | | | | |302
sptrembl|Q8KQ40|Q8KQ4 | __________________________________________________
Local hits (HSPs) | ________
Score = 68 (29.0 bits), Expect = 0.55, P = 0.42
Identities = 19/54 (35%), Positives = 30/54 (55%)
Query: 37 EMRELIQAKVGSFSQN-VELLNL-LPKRGPQAFDAFCEALRETKQGHLEDMLLT 88
E+R L+Q V S + +L LP+ P A DA +LR+ ++ HL+ +L T
Sbjct: 220 ELRNLLQQAVLSCRNGTIRASDLRLPRAAPAAPDAASASLRDMERAHLQSLLET 273
^ = sptrembl|Q31620|Q31620 B-G protein (Fragment).//:trembl|M61862|GGBGC_1 gene:
"B-G"; Chicken B-G mRNA, 3' end. //:pironly|D39371|D39371 Ig
V-region-like B-G antigen 17 - chicken
(fragment)//:gp|M61862|211261 B-G [Gallus gallus]
Length = 321
0 70 140 210 280
| | | | | |321
sptrembl|Q31620|Q3162 | __________________________________________________
Local hits (HSPs) | _______
Score = 68 (29.0 bits), Expect = 0.60, P = 0.45
Identities = 18/50 (36%), Positives = 31/50 (62%)
Query: 5 QETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVE 54
Q +L K R + ++L ++L EHL EKD+ T +++ L+ AK+ + VE
Sbjct: 164 QNSLLKKRYEITEELA-ADLEEHLAEKDLSTADLK-LLAAKLVEQREAVE 211
^ = trembl|AX089771|AX089771_1 unnamed ORF; Sequence 11 from Patent WO0116170.
//:gp|AX089771|13443944 unnamed protein product [synthetic
construct]
Length = 1424
0 290 580 870 1160
| | | | | |1424
trembl|AX089771|AX089 | __________________________________________________
Local hits (HSPs) | __
Score = 75 (31.5 bits), Expect = 0.63, P = 0.47
Identities = 19/70 (27%), Positives = 40/70 (57%)
Query: 8 LKKN-RVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
+K+N R + A+ L +L+ L + +++T +EL++ + S+N LL+++ K+G A
Sbjct: 1341 VKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLA 1400
Query: 67 FDAFCEALRE 76
D ++ E
Sbjct: 1401 LDVLFRSISE 1410
^ = trembl|AX089769|AX089769_1 unnamed ORF; Sequence 9 from Patent WO0116170.
//:gp|AX089769|13443942 unnamed protein product [synthetic
construct]
Length = 1454
0 290 580 870 1160 1450
| | | | | |1454
trembl|AX089769|AX089 | __________________________________________________
Local hits (HSPs) | __
Score = 75 (31.5 bits), Expect = 0.64, P = 0.47
Identities = 19/70 (27%), Positives = 40/70 (57%)
Query: 8 LKKN-RVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
+K+N R + A+ L +L+ L + +++T +EL++ + S+N LL+++ K+G A
Sbjct: 1371 VKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLA 1430
Query: 67 FDAFCEALRE 76
D ++ E
Sbjct: 1431 LDVLFRSISE 1440
^ = sptrembl|Q8R8A7|Q8R8A7 DNA-directed RNA polymerase sigma subunits
(sigma70/sigma32).//:trembl|AE013158|AE013158_1 gene: "RpoD5";
product: "DNA-directed RNA polymerase sigma subunits
(sigma70/sigma32)"; Thermoanaerobacter tengcongensis strain MB4T,
section 185 of 244 of the complete genome. //:gp|AE013158|20517120
DNA-directed RNA polymerase sigma subunits (sigma70/sigma32)
[Thermoanaerobacter tengcongensis]
Length = 265
0 60 120 180 240
| | | | | |265
sptrembl|Q8R8A7|Q8R8A | __________________________________________________
Local hits (HSPs) | ___________
Score = 66 (28.3 bits), Expect = 0.75, P = 0.53
Identities = 19/60 (31%), Positives = 30/60 (50%)
Query: 20 LLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQ 79
+L E LE L EK+ LEMR + + Q E+LN+ +R Q + LR +++
Sbjct: 195 ILKECLEVLPEKERSVLEMRYGLNGTPMTLKQIAEILNISKQRAGQIEKRALQRLRNSRK 254
^ = sptrembl|Q9HY73|Q9HY73 Probable ATP-binding component of ABC
transporter.//:tremblnew|AE004774|AE004774_4 gene: "PA3538";
product: "probable ATP-binding component of ABC transporter";
Pseudomonas aeruginosa PAO1, section 335 of 529 of the complete
genome. //:trembl|AE004774|AE004774_4 gene: "PA3538"; product:
"probable ATP-binding component of ABC transporter"; Pseudomonas
aeruginosa PA01, section 335 of 529 of the complete genome.
//:pironly|F83203|F83203 probable ATP-binding component of ABC
transporter PA3538 [imported] - Pseudomona//:gp|AE004774|9949688
probable ATP-binding component of ABC transporter [Pseudomonas
aeruginosa PA01] [Pseudomonas aeruginosa
PAO1]//:gpnew|AE004774|9949688 probable ATP-binding component of
ABC transporter [Pseudomonas aeruginosa PAO1]
Length = 360
0 80 160 240 320
| | | | | |360
sptrembl|Q9HY73|Q9HY7 | __________________________________________________
Local hits (HSPs) | ___________
Score = 67 (28.6 bits), Expect = 0.90, P = 0.59
Identities = 31/92 (33%), Positives = 44/92 (47%)
Query: 1 HPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
HPH ++ RV LA+ L LL LL++ L++ EL + S SQ V +L
Sbjct: 133 HPHELSGGQQQRVALARALAPEPLLL-LLDEPFSNLDV-ELRR----SLSQEVR--EILK 184
Query: 61 KRGPQAF-------DAF--CEALRETKQGHLE 83
RG A +AF C+ + K+GHLE
Sbjct: 185 ARGTSAILVTHDQEEAFAVCDHIGVFKEGHLE 216
^ = sptrembl|Q9Y1U6|Q9Y1U6 Cell death protein
CED-3.//:trembl|AF071505|AF071505_1 gene: "ced-3"; product: "cell
death protein CED-3"; Pristionchus pacificus cell death protein
CED-3 (ced-3) mRNA, complete cds. //:gp|AF071505|5305337 cell death
protein CED-3 [Pristionchus pacificus]
Length = 417
0 90 180 270 360
| | | | | |417
sptrembl|Q9Y1U6|Q9Y1U | __________________________________________________
Local hits (HSPs) | _______
Score = 67 (28.6 bits), Expect = 1.1, P = 0.66
Identities = 21/69 (30%), Positives = 37/69 (53%)
Query: 19 LLLSELLEHLLEKDIIT-LEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRET 77
L L +L++L K ++ ++ E+ + G ++L+ L K+G AFD F +L +
Sbjct: 24 LYLDPILDYLEVKQVLPESKINEIRRMSNG----RLDLMRSLTKQGSIAFDEFFLSLVHS 79
Query: 78 KQGHLEDML 86
+Q HL D L
Sbjct: 80 QQVHLADSL 88
^ = swissnew|P58801|RIK2_MOUSE Receptor-interacting serine/threonine protein
kinase 2 (EC 2.7.1.-).//:swiss|P58801|RIK2_MOUSE
Receptor-interacting serine/threonine protein kinase 2 (EC
2.7.1.-).//:sptremblnew|AAM76919|AAM76919 Protein kinase
RICK.//:trembl|AF461040|AF461040_1 gene: "Rip2"; product:
"receptor-interacting protein 2"; Mus musculus
receptor-interacting protein 2 (Rip2) mRNA, complete cds.
//:trembl|AF487539|AF487539_1 gene: "Ripk2"; product: "protein
kinase RICK"; Mus musculus protein kinase RICK (Ripk2) mRNA,
complete cds. //:gp|AF461040|19744302 receptor-interacting protein
2 [Mus musculus]//:gp|AF487539|21728338 protein kinase RICK [Mus
musculus]
Length = 539
0 110 220 330 440
| | | | | |539
swissnew|P58801|RIK2_ | __________________________________________________
Local hits (HSPs) | _______
Score = 68 (29.0 bits), Expect = 1.2, P = 0.69
Identities = 21/78 (26%), Positives = 39/78 (50%)
Query: 5 QETLKKNRVVLAKQLL---LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPK 61
Q+ ++ R + Q+ L++ L+ LL +D+I E ELI K S+ +LL+
Sbjct: 436 QQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTSKVRQLLDTSDI 495
Query: 62 RGPQAFDAFCEALRETKQ 79
+G + + L++ KQ
Sbjct: 496 QGEEFAKVVVQKLKDNKQ 513
^ = sptrembl|Q9XHU8|Q9XHU8 Hypothetical 9.4 kDa protein
(Fragment).//:trembl|AF056527|AF056527_1 gene: "AG3"; product:
"unknown"; Brassica napus cultivar Darmor AG3 gene, AG3-DN allele,
partial cds. //:gp|AF056527|5305236 unknown [Brassica napus]
Length = 80
0 20 40 60 80
| | | | |80
sptrembl|Q9XHU8|Q9XHU | __________________________________________________
Local hits (HSPs) | ______________________________
Score = 57 (25.1 bits), Expect = 1.3, P = 0.72
Identities = 12/50 (24%), Positives = 28/50 (56%)
Query: 11 NRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
NR+ K LL ++++ ++++ +L++AK+ +N +NL+P
Sbjct: 16 NRIRSKKNELLFAEIDYMQKREVDLHSENQLLRAKIAENERNNPSMNLMP 65
^ = sptrembl|Q90WU0|Q90WU0 Caspase 9 (Fragment).//:trembl|AY057940|AY057940_1
product: "caspase 9"; Gallus gallus caspase 9 mRNA, partial cds.
//:gp|AY057940|16555409 caspase 9 [Gallus gallus]
Length = 403
0 80 160 240 320 400
| | | | | |403
sptrembl|Q90WU0|Q90WU | __________________________________________________
Local hits (HSPs) | ___
Score = 66 (28.3 bits), Expect = 1.3, P = 0.74
Identities = 15/28 (53%), Positives = 16/28 (57%)
Query: 59 LPKRGPQAFDAFCEALRETKQGHLEDML 86
L RG QAF F LR+T G L DML
Sbjct: 44 LETRGKQAFPIFLSILRDTGHGDLADML 71
^ = sptrembl|Q8NLI1|Q8NLI1 Uncharacterized BCR.//:trembl|AP005283|AP005283_163
gene: "Cgl2961"; product: "Uncharacterized BCR"; Corynebacterium
glutamicum ATCC 13032 DNA, complete genome, section 10/10.
//:gp|AP005283|21325734 Uncharacterized BCR [Corynebacterium
glutamicum ATCC 13032]
Length = 220
0 50 100 150 200
| | | | | |220
sptrembl|Q8NLI1|Q8NLI | __________________________________________________
Local hits (HSPs) | _____ _____________
Score = 58 (25.5 bits), Expect = 1.4, Sum P(2) = 0.75
Identities = 9/25 (36%), Positives = 19/25 (76%)
Query: 2 PHHQETLKKNRVVLAKQLLLSELLE 26
PHHQ+ ++ + ++LAK + +E++E
Sbjct: 80 PHHQQAVEMSEILLAKDDIPAEVIE 104
Score = 38 (18.4 bits), Expect = 1.4, Sum P(2) = 0.75
Identities = 12/63 (19%), Positives = 29/63 (46%)
Query: 21 LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQG 80
++ +LE E+D +T +M E+ + ++ L +G +A + E + +G
Sbjct: 120 MNTMLE-TWEEDPVTGDMGEMDHGGMSGMMSEEDMTALEDAQGTEAARLYLEQMTAHHEG 178
Query: 81 HLE 83
++
Sbjct: 179 AVD 181
^ = sptrembl|Q8K5C7|Q8K5C7 Melanoma differentiation associated gene 5-like
protein.//:trembl|AF374384|AF374384_1 product: "melanoma
differentiation associated gene 5-like protein"; Mus musculus
strain C57BL/6J melanoma differentiation associated gene 5-like
protein mRNA, complete cds. //:gp|AF374384|20385628 melanoma
differentiation associated gene 5-like protein [Mus musculus]
Length = 1025
0 210 420 630 840
| | | | | |1025
sptrembl|Q8K5C7|Q8K5C | __________________________________________________
Local hits (HSPs) | ___
Score = 70 (29.7 bits), Expect = 1.5, P = 0.78
Identities = 20/65 (30%), Positives = 37/65 (56%)
Query: 15 LAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNV--ELLNLLPKRGPQAFDAFCE 72
L +LL++++L+ EK ++T+E R I A S +++ ELL + ++ F F +
Sbjct: 125 LVDKLLINDVLDTCFEKGLLTVEDRNRISAAGNSGNESGVRELLRRIVQK-ENWFSTFLD 183
Query: 73 ALRET 77
LR+T
Sbjct: 184 VLRQT 188
^ = swissnew|O43353|RIK2_HUMAN Receptor-interacting serine/threonine protein
kinase 2 (EC 2.7.1.-) (RIP-like interacting CLARP kinase)
(Receptor-interacting protein 2) (RIP-2) (CARD-containing
interleukin-1 beta converting enzyme associated kinase)
(CARD-containing IL-1 beta ICE-kinase).//:swiss|O43353|RIK2_HUMAN
Receptor-interacting serine/threonine protein kinase 2 (EC 2.7.1.-)
(RIP-like interacting CLARP kinase) (Receptor-interacting protein
2) (RIP-2) (CARD-containing interleukin-1 beta converting enzyme
associated kinase) (CARD-containing IL-1 beta
ICE-kinase).//:trembl|AC004003|AC004003_1 gene:
"WUGSC:H_RG437L15.1"; Homo sapiens BAC clone CTA-437L15 from 8q21,
complete sequence. //:trembl|AF027706|AF027706_1 gene: "RICK";
product: "serine/threonine kinase RICK"; Homo sapiens
serine/threonine kinase RICK (RICK) mRNA, complete cds.
//:trembl|AF064824|AF064824_1 product: "CARD-containing ICE
associated kinase"; Homo sapiens CARD-containing ICE associated
kinase mRNA, complete cds. //:trembl|AF078530|AF078530_1 gene:
"RIP2"; product: "receptor interacting protein 2"; Homo sapiens
receptor interacting protein 2 (RIP2) mRNA, complete cds.
//:trembl|AF117829|AF117829_1 gene: "RICK"; product:
"serine/threonine kinase RICK"; Homo sapiens 8q21.3: RICK gene,
complete sequence. //:trembl|BC004553|BC004553_1 product:
"receptor-interacting serine-threonine kinase 2"; Homo sapiens,
receptor-interacting serine-threonine kinase 2, clone MGC:10684
IMAGE:4026156, mRNA, complete cds. //:gp|AF064824|3290172
CARD-containing ICE associated kinase [Homo
sapiens]//:gp|AF078530|3342910 receptor interacting protein 2 [Homo
sapiens]//:gp|AF027706|3123887 serine/threonine kinase RICK [Homo
sapiens]//:gp|AF117829|4151948 serine/threonine kinase RICK [Homo
sapiens]//:gp|AC004003|3264574 serine/threonine kinase RICK; match
to protein AF027706 (PID:g3123887) and mRNA AF027706 (NID:g3123886)
[Homo sapiens]//:gp|BC004553|13528714 receptor-interacting
serine-threonine kinase 2 [Homo sapiens]
Length = 540
0 110 220 330 440
| | | | | |540
swissnew|O43353|RIK2_ | __________________________________________________
Local hits (HSPs) | _______
Score = 67 (28.6 bits), Expect = 1.5, P = 0.78
Identities = 21/82 (25%), Positives = 41/82 (50%)
Query: 5 QETLKKNRVVLAKQLL---LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPK 61
Q+ ++ R + Q+ L++ L+ LL +D+I E EL+ K S+ +LL+
Sbjct: 437 QQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDI 496
Query: 62 RGPQAFDAFCEALRETKQGHLE 83
+G + + L++ KQ L+
Sbjct: 497 QGEEFAKVIVQKLKDNKQMGLQ 518
^ = sptrembl|Q9XHU4|Q9XHU4 Hypothetical 8.5 kDa protein
(Fragment).//:trembl|AF056531|AF056531_1 gene: "AG2"; product:
"unknown"; Brassica oleracea cultivar Rapide Cycling AG2 gene,
AG2-RC allele, partial cds. //:gp|AF056531|5305244 unknown
[Brassica oleracea]
Length = 73
0 20 40 60
| | | | |73
sptrembl|Q9XHU4|Q9XHU | __________________________________________________
Local hits (HSPs) | _________________________________
Score = 56 (24.8 bits), Expect = 1.6, P = 0.80
Identities = 12/50 (24%), Positives = 28/50 (56%)
Query: 11 NRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLP 60
NR+ K LL ++++ ++++ +L++AK+ +N +NL+P
Sbjct: 10 NRIRSKKNELLFAEIDYMQKREVDLHSDNQLLRAKIAENERNNPSMNLMP 59
^ = swissnew|Q13489|BIR2_HUMAN Baculoviral IAP repeat-containing protein 2
(Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2)
(TNFR2-TRAF signaling complex protein 1) (IAP homolog
C).//:swiss|Q13489|BIR2_HUMAN Baculoviral IAP repeat-containing
protein 2 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1)
(C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog
C).//:sptremblnew|AAH37420|AAH37420 Hypothetical
protein.//:trembl|BC037420|BC037420_1 product: "Unknown (protein
for MGC:46142)"; Homo sapiens, clone MGC:46142 IMAGE:5497880,
mRNA, complete cds. //:trembl|U37546|HS375461_1 gene: "MIHC";
product: "MIHC"; Human IAP homolog C (MIHC) mRNA, complete cds.
//:trembl|L49432|HSSCPB_1 product: "TNFR2-TRAF signalling complex
protein"; Homo sapiens TNFR2-TRAF signalling complex protein mRNA,
complete cds. //:gp|L49432|1160975 TNFR2-TRAF signalling complex
protein [Homo sapiens]//:gp|U37546|1145291 MIHC [Homo
sapiens]//:gp|BC037420|22766816 Unknown (protein for MGC:46142)
[Homo sapiens]
Length = 604
0 120 240 360 480 600
| | | | | |604
swissnew|Q13489|BIR2_ | __________________________________________________
Local hits (HSPs) | _____
Score = 67 (28.6 bits), Expect = 1.7, P = 0.82
Identities = 20/72 (27%), Positives = 39/72 (54%)
Query: 8 LKKNRVVLAKQLL-LSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA 66
++KNR+ L + L + +L+ LL II + ++I+ K + Q EL++ + +G A
Sbjct: 447 IRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIA 506
Query: 67 FDAFCEALRETK 78
F +L+E +
Sbjct: 507 ATVFRNSLQEAE 518
WARNING: HSPs involving 22 database sequences were not reported due to the
limiting value of parameter B = 50.
Parameters:
matrix=BLOSUM62
E=10
V=250
B=50
hspmax=10
filter=none
echofilter
stats
qtype
qres
ctxfactor=1.00
Query ----- As Used ----- ----- Computed ----
Frame MatID Matrix name Lambda K H Lambda K H
+0 0 BLOSUM62 0.319 0.136 0.373 same same same
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
Query
Frame MatID Length Eff.Length E S W T X E2 S2
+0 0 89 89 10. 66 3 11 22 0.23 29
28 0.25 30
Statistics:
Query Expected Observed HSPs HSPs
Frame MatID High Score High Score Reportable Reported
+0 0 64 (29.5 bits) 448 (206.4 bits) 75 51
Query Neighborhd Word Excluded Failed Successful Overlaps
Frame MatID Words Hits Hits Extensions Extensions Excluded
+0 0 1568 33702244 6054100 27428752 219392 696
Database: /dove2/data/db/nrdb95
Title: nrdb-95%
Release date: unknown
Posted date: 11:14:02 AM MET Mar 21, 2003
Last modified: unknown
First created: unknown
Format: BLAST-1.4
# of letters in database: 229,823,634
# of sequences in database: 701,238
# of database sequences satisfying E: 72
No. of states in DFA: 446 (88 KB)
Total size of DFA: 123 KB (128 KB)
Time to generate neighborhood: 0.02u 0.00s 0.02t Elapsed: 00:00:00
No. of threads or processors used: 4
Search cpu time: 62.08u 2.72s 64.80t Elapsed: 00:00:17
Total cpu time: 62.14u 2.81s 64.95t Elapsed: 00:00:17
Start: Tue Apr 1 15:25:29 2003 End: Tue Apr 1 15:25:46 2003
WARNINGS ISSUED: 1
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