gi|2507533|sp|P06132|DCUP_HUMAN gi|3660278|pdb|1URO|A gi|2905794|gb|AAC03563.1|
Score = 137 bits (346), Expect(2) = 7e-40
Identities = 79/133 (59%), Positives = 80/133 (60%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 52.4 bits (124), Expect(2) = 7e-40
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 291 ARECVGKTVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|12804699|gb|AAH01778.1| gi|30582313|gb|AAP35383.1|
Score = 137 bits (346), Expect(2) = 7e-39
Identities = 79/133 (59%), Positives = 80/133 (60%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 48.9 bits (115), Expect(2) = 7e-39
Identities = 22/24 (91%), Positives = 23/24 (95%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQ NLDPCALYASE
Sbjct: 291 ARECVGKTVTLQVNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|9845522|ref|NP_000365.2| gi|7436550|pir||G02786 uroporphyrinogen decarboxylase - human
gi|1322019|gb|AAC50482.1| gi|1418944|emb|CAA61540.1| gi|4151813|gb|AAD04571.1| gi|4151815|gb|AAD04572.1| gi|4151817|gb|AAD04573.1| gi|4151819|gb|AAD04574.1| gi|4151821|gb|AAD04575.1| gi|4151823|gb|AAD04576.1| gi|4151825|gb|AAD04577.1| gi|4151827|gb|AAD04578.1| gi|4151829|gb|AAD04579.1| gi|4151831|gb|AAD04580.1| gi|4151833|gb|AAD04581.1| gi|4151835|gb|AAD04582.1| gi|4151837|gb|AAD04583.1| gi|4151839|gb|AAD04584.1| gi|4151841|gb|AAD04585.1| gi|4151843|gb|AAD04586.1| gi|4151845|gb|AAD04587.1| gi|4151847|gb|AAD04588.1| gi|4151849|gb|AAD04589.1| gi|4151851|gb|AAD04590.1| gi|31323304|gb|AAP44118.1| uroporphyrinogen decarboxylase [Homo sapiens]
Length = 367
Score = 215 bits (548), Expect = 5e-54
Identities = 119/160 (74%), Positives = 120/160 (75%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL
Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 151
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGFAGAP W + MTYMVEGGGSS
Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ
Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
Score = 137 bits (346), Expect(2) = 7e-40
Identities = 79/133 (59%), Positives = 80/133 (60%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 87.0 bits (214), Expect(3) = 3e-35
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 3e-35
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 52.4 bits (124), Expect(2) = 7e-40
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 291 ARECVGKTVTLQGNLDPCALYASE 314
Score = 47.0 bits (110), Expect(3) = 3e-35
Identities = 23/23 (100%), Positives = 23/23 (100%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRFLLDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFLLDAAIIFSDILVVPQ 92
gi|18158958|pdb|1JPH|A
Score = 136 bits (342), Expect(2) = 2e-39
Identities = 79/133 (59%), Positives = 79/133 (59%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM
Sbjct: 234 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM-------------- 279
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
I FAKDGHFALEELAQAGYEV
Sbjct: 280 ---------------------------------------ITFAKDGHFALEELAQAGYEV 300
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 301 VGLDWTVAPKKAR 313
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 330 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 388
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 29 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 65
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 66 EFRETRAAQDFFSTCRSPEACCELTLQ 92
Score = 52.4 bits (124), Expect(2) = 2e-39
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 312 ARECVGKTVTLQGNLDPCALYASE 335
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 91 LQPLRRFPLDAAIIFSDILVVPQ 113
gi|18158959|pdb|1JPI|A
Score = 135 bits (340), Expect(2) = 3e-39
Identities = 78/133 (58%), Positives = 79/133 (59%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNK ALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 234 ALQLFESHAGHLGPQLFNKLALPYIRDVAKQVKARLREAGLAPVPMI------------- 280
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 281 ----------------------------------------IFAKDGHFALEELAQAGYEV 300
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 301 VGLDWTVAPKKAR 313
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 330 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 388
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 29 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 65
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 66 EFRETRAAQDFFSTCRSPEACCELTLQ 92
Score = 52.4 bits (124), Expect(2) = 3e-39
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 312 ARECVGKTVTLQGNLDPCALYASE 335
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 91 LQPLRRFPLDAAIIFSDILVVPQ 113
gi|30584783|gb|AAP36644.1| Homo sapiens uroporphyrinogen decarboxylase [synthetic construct]
Length = 368
Score = 215 bits (548), Expect = 5e-54
Identities = 119/160 (74%), Positives = 120/160 (75%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL
Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 151
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGFAGAP W + MTYMVEGGGSS
Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ
Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
Score = 137 bits (346), Expect(2) = 7e-39
Identities = 79/133 (59%), Positives = 80/133 (60%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 48.9 bits (115), Expect(2) = 7e-39
Identities = 22/24 (91%), Positives = 23/24 (95%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQ NLDPCALYASE
Sbjct: 291 ARECVGKTVTLQVNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|18158960|pdb|1JPK|A
Score = 137 bits (346), Expect(2) = 7e-40
Identities = 79/133 (59%), Positives = 80/133 (60%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 234 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 280
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 281 ----------------------------------------IFAKDGHFALEELAQAGYEV 300
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 301 VGLDWTVAPKKAR 313
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 330 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 388
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 29 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 65
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 66 EFRETRAAQDFFSTCRSPEACCELTLQ 92
Score = 52.4 bits (124), Expect(2) = 7e-40
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 312 ARECVGKTVTLQGNLDPCALYASE 335
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 91 LQPLRRFPLDAAIIFSDILVVPQ 113
gi|88979|pir||A24411 uroporphyrinogen decarboxylase (EC 4.1.1.37) - human
gi|340181|gb|AAA61258.1|
Score = 137 bits (346), Expect(2) = 7e-40
Identities = 79/133 (59%), Positives = 80/133 (60%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 87.0 bits (214), Expect(3) = 2e-34
Identities = 37/37 (100%), Positives = 37/37 (100%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 2e-34
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 52.4 bits (124), Expect(2) = 7e-40
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 291 ARECVGKTVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 2e-34
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|340183|gb|AAB59456.1|
Score = 92.0 bits (227), Expect = 9e-17
Identities = 44/44 (100%), Positives = 44/44 (100%)
Frame = +3
Query: 3285 QLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 3416
QLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM
Sbjct: 118 QLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 161
gi|27527067|emb|CAC82649.1| uroporphyrinogen decarboxylase [Ovis aries]
Length = 367
Score = 206 bits (523), Expect = 4e-51
Identities = 113/160 (70%), Positives = 117/160 (73%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QALGMEVTMVPGKGPSFPEPLREE+DLERLRDP VASELGYVFQAITLTRQ+LAGRVPL
Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELGYVFQAITLTRQQLAGRVPL 151
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGFAGAP W + MTYMVEGGGSS
Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
TM+QAKRWLYQRPQASHQLLRILTDALVPYLVGQV AGAQ
Sbjct: 173 TMSQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQ 212
Score = 127 bits (319), Expect(2) = 2e-35
Identities = 73/133 (54%), Positives = 79/133 (59%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLGPQLF+KFALPYIRDV+K+VKA L+EAGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGPQLFSKFALPYIRDVSKRVKAGLQEAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAP+KAR
Sbjct: 280 VGLDWTVAPEKAR 292
Score = 110 bits (275), Expect = 2e-22
Identities = 51/59 (86%), Positives = 55/59 (93%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGKLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 89.4 bits (220), Expect(3) = 4e-35
Identities = 38/39 (97%), Positives = 39/39 (100%)
Frame = +3
Query: 1743 ARPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
+RPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 6 SRPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 4e-35
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 47.8 bits (112), Expect(2) = 2e-35
Identities = 22/24 (91%), Positives = 23/24 (95%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RE VGKTVTLQGNLDPCALYASE
Sbjct: 291 ARERVGKTVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 4e-35
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|14198090|gb|AAH08109.1|
Score = 124 bits (311), Expect(2) = 6e-34
Identities = 72/133 (54%), Positives = 78/133 (58%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGTELFSKFALPYIRDVAKRVKAGLQKAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 109 bits (272), Expect = 5e-22
Identities = 51/59 (86%), Positives = 54/59 (91%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIG+LV+QMLDDFGP RYIANLGHGLYPDMDPE VGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGRLVQQMLDDFGPQRYIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN 367
Score = 82.0 bits (201), Expect(3) = 6e-33
Identities = 35/36 (97%), Positives = 35/36 (97%)
Frame = +3
Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 9 QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 6e-33
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 45.8 bits (107), Expect(2) = 6e-34
Identities = 21/24 (87%), Positives = 22/24 (91%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RE VGK VTLQGNLDPCALYASE
Sbjct: 291 ARERVGKAVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 6e-33
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|6678517|ref|NP_033504.1| gi|2501645|sp|P70697|DCUP_MOUSE gi|7436557|pir||T10088 uroporphyrinogen decarboxylase (EC 4.1.1.37) - mouse
gi|1498643|gb|AAB18294.1|
Score = 124 bits (311), Expect(2) = 6e-34
Identities = 72/133 (54%), Positives = 78/133 (58%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGLAPVPM+
Sbjct: 213 ALQLFESHAGHLGTELFSKFALPYIRDVAKRVKAGLQKAGLAPVPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 105 bits (263), Expect = 6e-21
Identities = 50/59 (84%), Positives = 53/59 (89%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIG+LV+QMLDDFGP R IANLGHGLYPDMDPE VGAFVDAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGRLVQQMLDDFGPQRSIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN 367
Score = 82.0 bits (201), Expect(3) = 6e-33
Identities = 35/36 (97%), Positives = 35/36 (97%)
Frame = +3
Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 9 QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 6e-33
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 45.8 bits (107), Expect(2) = 6e-34
Identities = 21/24 (87%), Positives = 22/24 (91%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RE VGK VTLQGNLDPCALYASE
Sbjct: 291 ARERVGKAVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 6e-33
Identities = 22/23 (95%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
gi|34870275|ref|XP_342888.1|
Score = 124 bits (311), Expect(2) = 2e-34
Identities = 72/133 (54%), Positives = 78/133 (58%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGLAPVPM+
Sbjct: 220 ALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAGLAPVPMI------------- 266
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 267 ----------------------------------------IFAKDGHFALEELAQAGYEV 286
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 287 VGLDWTVAPKKAR 299
Score = 110 bits (275), Expect = 2e-22
Identities = 51/59 (86%), Positives = 55/59 (93%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 316 ALYASEEEIGRLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 374
Score = 85.5 bits (210), Expect(3) = 1e-33
Identities = 38/41 (92%), Positives = 38/41 (92%)
Frame = +3
Query: 1737 LIARPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LI R Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 11 LIRRLQNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 51
Score = 60.8 bits (146), Expect(3) = 1e-33
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 52 EFRETRAAQDFFSTCRSPEACCELTLQ 78
Score = 47.8 bits (112), Expect(2) = 2e-34
Identities = 22/24 (91%), Positives = 23/24 (95%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RE VGKTVTLQGNLDPCALYASE
Sbjct: 298 ARERVGKTVTLQGNLDPCALYASE 321
Score = 43.1 bits (100), Expect(3) = 1e-33
Identities = 21/23 (91%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLR+F LDAAIIFSDILVVPQ
Sbjct: 77 LQPLRKFPLDAAIIFSDILVVPQ 99
gi|225691|prf||1310344A decarboxylase,uroporphyrinogen
Length = 367
Score = 189 bits (479), Expect = 5e-46
Identities = 105/160 (65%), Positives = 110/160 (68%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QAL MEVTMVPGKGPSFPEPLREE+DLERLRDP VASELGYVFQAITLTRQRLAGRVPL
Sbjct: 92 QALAMEVTMVPGKGPSFPEPLREERDLERLRDPAAVASELGYVFQAITLTRQRLAGRVPL 151
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGFAGAP W + MTYMVEGG
Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGSFK 172
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
TMAQAKRWLYQ+P ASH+LL ILT ALVPYL+GQV AGAQ
Sbjct: 173 TMAQAKRWLYQKPVASHKLLGILTHALVPYLIGQVAAGAQ 212
Score = 118 bits (295), Expect(2) = 5e-32
Identities = 69/133 (51%), Positives = 76/133 (57%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGL +PM+
Sbjct: 213 ALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAGLTRMPMI------------- 259
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 280 VGLDWTVAPKKAR 292
Score = 109 bits (272), Expect = 5e-22
Identities = 50/59 (84%), Positives = 55/59 (93%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAF+DAVHKHSRLLRQN
Sbjct: 309 ALYASEEEIGRLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFLDAVHKHSRLLRQN 367
Score = 77.0 bits (188), Expect(3) = 4e-31
Identities = 34/36 (94%), Positives = 34/36 (94%)
Frame = +3
Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
Q FPELKNDTFLRAA GEETDYTPVWCMRQAGRYLP
Sbjct: 9 QNFPELKNDTFLRAATGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 4e-31
Identities = 27/27 (100%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTLQ
Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 45.4 bits (106), Expect(2) = 5e-32
Identities = 21/24 (87%), Positives = 22/24 (91%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RE VGKTVTLQG LDPCALYASE
Sbjct: 291 AREPVGKTVTLQGELDPCALYASE 314
Score = 43.1 bits (100), Expect(3) = 4e-31
Identities = 21/23 (91%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQP+RRF LDAAIIFSDILVVPQ
Sbjct: 70 LQPVRRFPLDAAIIFSDILVVPQ 92
gi|416892|sp|P32362|DCUP_RAT Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|5524747|emb|CAB50784.1|
Score = 118 bits (295), Expect(2) = 5e-32
Identities = 69/133 (51%), Positives = 76/133 (57%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGL +PM+
Sbjct: 210 ALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAGLTRMPMI------------- 256
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
IFAKDGHFALEELAQAGYEV
Sbjct: 257 ----------------------------------------IFAKDGHFALEELAQAGYEV 276
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWTVAPKKAR
Sbjct: 277 VGLDWTVAPKKAR 289
Score = 109 bits (272), Expect = 5e-22
Identities = 50/59 (84%), Positives = 55/59 (93%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAF+DAVHKHSRLLRQN
Sbjct: 306 ALYASEEEIGRLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFLDAVHKHSRLLRQN 364
Score = 82.0 bits (201), Expect(3) = 7e-32
Identities = 35/36 (97%), Positives = 35/36 (97%)
Frame = +3
Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
Sbjct: 6 QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 41
Score = 59.7 bits (143), Expect(3) = 7e-32
Identities = 26/27 (96%), Positives = 27/27 (100%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRETRAAQDFFSTCRSPEACCELTL+
Sbjct: 42 EFRETRAAQDFFSTCRSPEACCELTLE 68
Score = 45.4 bits (106), Expect(2) = 5e-32
Identities = 21/24 (87%), Positives = 22/24 (91%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RE VGKTVTLQG LDPCALYASE
Sbjct: 288 AREPVGKTVTLQGELDPCALYASE 311
Score = 42.0 bits (97), Expect(3) = 7e-32
Identities = 20/23 (86%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
L+P+RRF LDAAIIFSDILVVPQ
Sbjct: 67 LEPVRRFPLDAAIIFSDILVVPQ 89
gi|18859531|ref|NP_571422.1| gi|20138048|sp|Q9PTS2|DCUP_BRARE gi|6502530|gb|AAF14346.1|
Score = 88.6 bits (218), Expect(2) = 3e-19
Identities = 48/133 (36%), Positives = 68/133 (51%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458
ALQ+FESH G LGP F +F+LPY+RD+A++VK +++E+GL VPM+
Sbjct: 215 ALQVFESHTGCLGPVEFKEFSLPYLRDIARRVKDKIKESGLDNVPMI------------- 261
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
+FAKDGH+ LE+L+++ YEV
Sbjct: 262 ----------------------------------------VFAKDGHYGLEDLSESAYEV 281
Query: 3639 VGLDWTVAPKKAR 3677
VGLDWT+ P+ AR
Sbjct: 282 VGLDWTIDPRSAR 294
Score = 80.5 bits (197), Expect = 3e-13
Identities = 40/68 (58%), Positives = 48/68 (70%)
Frame = +3
Query: 4125 GGQRLAGPPVASALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDA 4304
G L G AL +E I ++V++ML+ FG YIANLGHGLYPDMDPE+VGAFV+A
Sbjct: 299 GKVSLQGNMDPCALYGTKESISEIVRRMLEGFGTKGYIANLGHGLYPDMDPENVGAFVEA 358
Query: 4305 VHKHSRLL 4328
VH HSR L
Sbjct: 359 VHNHSRQL 366
Score = 68.2 bits (165), Expect(3) = 1e-26
Identities = 29/37 (78%), Positives = 33/37 (89%)
Frame = +3
Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
P+ FPEL+NDTFLRAA GEE ++ PVWCMRQAGRYLP
Sbjct: 10 PKDFPELRNDTFLRAARGEEIEHIPVWCMRQAGRYLP 46
Score = 54.7 bits (130), Expect(3) = 1e-26
Identities = 23/27 (85%), Positives = 25/27 (92%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EFRE+RA +DFF TCRSPEACCELTLQ
Sbjct: 47 EFRESRAGKDFFETCRSPEACCELTLQ 73
Score = 42.7 bits (99), Expect(3) = 1e-26
Identities = 21/23 (91%), Positives = 21/23 (91%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
LQPLRRF DAAIIFSDILVVPQ
Sbjct: 72 LQPLRRFPFDAAIIFSDILVVPQ 94
Score = 32.3 bits (72), Expect(2) = 3e-19
Identities = 13/25 (52%), Positives = 19/25 (76%)
Frame = +1
Query: 3772 ASRECVGKTVTLQGNLDPCALYASE 3846
++R G V+LQGN+DPCALY ++
Sbjct: 292 SARVRTGGKVSLQGNMDPCALYGTK 316
gi|19075585|ref|NP_588085.1| probable uroporphyrinogen decarboxylase [Schizosaccharomyces pombe]
gi|8928074|sp|Q9USJ5|DCUP_SCHPO Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|11267829|pir||T50443 probable uroporphyrinogen decarboxylase [imported] - fission yeast
(Schizosaccharomyces pombe)
gi|6434013|emb|CAB60679.1| SPCC4B3.05c [Schizosaccharomyces pombe]
Length = 370
Score = 127 bits (319), Expect = 2e-27
Identities = 69/161 (42%), Positives = 96/161 (59%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QALGM+V M+ KGP FP+PL +D++ L ++++LGYV AI+LTR++L G+VPL
Sbjct: 96 QALGMQVVMLEQKGPHFPKPLVVPEDIDLLEKTPNISAKLGYVMDAISLTREKLDGQVPL 155
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
+GF+GAP W + M YM+EGGGS
Sbjct: 156 MGFSGAP---------------WTI------------------------MAYMIEGGGSK 176
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913
T A+AK WL++ P+ASH+LL+I+TDA V YL+ QV AGAQ+
Sbjct: 177 TFAKAKSWLFRYPEASHKLLKIITDATVSYLIQQVYAGAQL 217
Score = 59.3 bits (142), Expect(2) = 2e-08
Identities = 36/131 (27%), Positives = 57/131 (43%)
Frame = +3
Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461
LQ+F+S AG L P+ F ++A PY+ + ++VK L++ VPM
Sbjct: 218 LQIFDSWAGELSPEDFTEYAYPYLVRICQEVKQHLKKKKRDEVPM--------------- 262
Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641
I+FAK +A+++L +GY+V+
Sbjct: 263 --------------------------------------IVFAKGAWYAIDQLCDSGYDVI 284
Query: 3642 GLDWTVAPKKA 3674
GLDWTV+PK+A
Sbjct: 285 GLDWTVSPKEA 295
Score = 40.4 bits (93), Expect = 0.30
Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = +3
Query: 4176 QEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVHKH 4316
+E I K+M+ DFG + YI NLGHG+ P ++P+ V F++ H++
Sbjct: 319 REIIEARTKEMIQDFGGGKQGYIINLGHGITPGVNPDDVRFFLEKCHQY 367
Score = 38.1 bits (87), Expect(2) = 4e-06
Identities = 20/25 (80%), Positives = 22/25 (88%), Gaps = 2/25 (8%)
Frame = +2
Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQ 2194
LQP+ RF LLDAAIIFSDILV+PQ
Sbjct: 72 LQPVTRFKGLLDAAIIFSDILVIPQ 96
Score = 38.1 bits (87), Expect(2) = 4e-06
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
E+ + RA Q FF C++PE CELTLQ
Sbjct: 47 EYHKLRAKQSFFEMCQTPETACELTLQ 73
Score = 24.6 bits (52), Expect(2) = 2e-08
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 3793 KTVTLQGNLDPCALYAS 3843
+ VT QGNLDP LY +
Sbjct: 302 RRVTFQGNLDPNILYGT 318
gi|4140696|gb|AAD04168.1| uroporphyrinogen decarboxylase [Homo sapiens]
Length = 109
Score = 118 bits (296), Expect = 9e-25
Identities = 55/59 (93%), Positives = 56/59 (94%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337
AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Sbjct: 51 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 109
Score = 72.4 bits (176), Expect(2) = 2e-20
Identities = 34/34 (100%), Positives = 34/34 (100%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR
Sbjct: 1 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 34
Score = 52.4 bits (124), Expect(2) = 2e-20
Identities = 23/24 (95%), Positives = 24/24 (100%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846
+RECVGKTVTLQGNLDPCALYASE
Sbjct: 33 ARECVGKTVTLQGNLDPCALYASE 56
gi|6320252|ref|NP_010332.1| fifth enzyme in the heme biosynthetic pathway; Hem12p [Saccharomyces
cerevisiae]
gi|416894|sp|P32347|DCUP_YEAST Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|283290|pir||S23471 uroporphyrinogen decarboxylase (EC 4.1.1.37) - yeast (Saccharomyces
cerevisiae)
gi|3767|emb|CAA45253.1| uroporphyrinogen decarboxylase [Saccharomyces cerevisiae]
gi|4776|emb|CAA79514.1| uroporphyrinogen decarboxylase [Saccharomyces cerevisiae]
gi|798900|emb|CAA89078.1| Hem12p [Saccharomyces cerevisiae]
Length = 362
Score = 109 bits (273), Expect = 4e-22
Identities = 66/162 (40%), Positives = 85/162 (52%), Gaps = 1/162 (0%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEV-VASELGYVFQAITLTRQRLAGRVP 2607
QA+GM V M+ GKGP FPEPLR +DL+ + D +V V EL + F+AIT+TR +L G VP
Sbjct: 87 QAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVP 146
Query: 2608 LIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGS 2787
L GF G P W + M YM EGGGS
Sbjct: 147 LFGFCGGP---------------WTL------------------------MVYMTEGGGS 167
Query: 2788 STMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913
AK+W+ P+ SH+LL+ +TD V +L QVVAGAQ+
Sbjct: 168 RLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQI 209
Score = 51.2 bits (121), Expect = 2e-04
Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 1/132 (0%)
Frame = +3
Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAP-VPMVRIGMG*VKVVLWS 3458
LQ+FES G L F++F+LPY+R +A++V RL+E G+ +PM
Sbjct: 210 LQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPM-------------- 255
Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638
I+FAK +AL++L +G++V
Sbjct: 256 ---------------------------------------IVFAKGSWYALDKLCCSGFDV 276
Query: 3639 VGLDWTVAPKKA 3674
V LDW+ P++A
Sbjct: 277 VSLDWSWDPREA 288
Score = 48.5 bits (114), Expect = 0.001
Identities = 22/34 (64%), Positives = 24/34 (70%)
Frame = +3
Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
FP KND LRAA GE+ + P W MRQAGRYLP
Sbjct: 4 FPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLP 37
Score = 44.3 bits (103), Expect = 0.021
Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 2/48 (4%)
Frame = +3
Query: 4176 QEEIGQLVKQMLDDFG--PHRYIANLGHGLYPDMDPEHVGAFVDAVHK 4313
+E I + VKQM++ FG RYI N GHG +P MDP+ + F++ H+
Sbjct: 311 KEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECHR 358
Score = 37.7 bits (86), Expect(2) = 2e-04
Identities = 18/25 (72%), Positives = 23/25 (92%), Gaps = 2/25 (8%)
Frame = +2
Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQ 2194
+QP+RR+ L+DAAIIFSDILV+PQ
Sbjct: 63 IQPVRRYRGLIDAAIIFSDILVIPQ 87
Score = 32.3 bits (72), Expect(2) = 2e-04
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +1
Query: 1900 GEKFSRGRGGLWR-ASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQVRGPQKR 2076
GEK R + R A R P E+ E + +DFF TCR E E+T+Q P +R
Sbjct: 18 GEKVERPPCWIMRQAGRYLP------EYHEVKNNRDFFQTCRDAEIASEITIQ---PVRR 68
Query: 2077 ER 2082
R
Sbjct: 69 YR 70
gi|31240435|ref|XP_320631.1| ENSANGP00000021292 [Anopheles gambiae]
gi|30174144|gb|EAA00166.2| ENSANGP00000021292 [Anopheles gambiae str. PEST]
Length = 351
Score = 109 bits (272), Expect = 5e-22
Identities = 69/161 (42%), Positives = 84/161 (52%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QALG+ V M PG GP PEPL DL+RL + L YV +AIT+ R+ L G+VPL
Sbjct: 83 QALGITVEMKPGVGPVLPEPLVGPADLDRLNQTGTI-ERLKYVGEAITMMRRMLEGKVPL 141
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
GF GAP W + G YM+EGGGS
Sbjct: 142 FGFTGAP---------------WTLMG------------------------YMIEGGGSK 162
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913
TM++AK WL P+AS +LL ILTD +V YLV QV AGAQ+
Sbjct: 163 TMSKAKGWLADHPEASQKLLDILTDQVVDYLVMQVKAGAQM 203
Score = 54.7 bits (130), Expect(3) = 1e-18
Identities = 25/34 (73%), Positives = 25/34 (73%)
Frame = +3
Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
FP LKND LRAA GE D PVW MRQAGRYLP
Sbjct: 2 FPPLKNDNLLRAARGEPVDRVPVWVMRQAGRYLP 35
Score = 54.3 bits (129), Expect(2) = 3e-08
Identities = 36/132 (27%), Positives = 54/132 (40%)
Frame = +3
Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461
LQ+FES A HL + F +LP ++ + + +L + G+ VPM
Sbjct: 204 LQVFESSADHLSKEQFLSVSLPCLKRIRVDLLRKLADEGVPAVPM--------------- 248
Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641
++FAK +LEE+AQ GYEV+
Sbjct: 249 --------------------------------------VLFAKGAMHSLEEMAQTGYEVL 270
Query: 3642 GLDWTVAPKKAR 3677
GLDWT+ P++AR
Sbjct: 271 GLDWTIDPEEAR 282
Score = 51.6 bits (122), Expect = 1e-04
Identities = 24/46 (52%), Positives = 29/46 (63%)
Frame = +3
Query: 4173 PQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVH 4310
P EE+ +LV M+ FG HRYIANLGHG+ P E + V AVH
Sbjct: 303 PPEELRELVLTMVRKFGKHRYIANLGHGITPQTPIESMSVLVQAVH 348
Score = 42.0 bits (97), Expect(3) = 1e-18
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EF+E RA DFF+ CR+PE CE+T+Q
Sbjct: 36 EFQEVRAKHDFFTVCRTPELACEVTMQ 62
Score = 41.6 bits (96), Expect(3) = 1e-18
Identities = 19/23 (82%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
+QPLRRF LDA+IIFSDILV+PQ
Sbjct: 61 MQPLRRFDLDASIIFSDILVIPQ 83
Score = 29.3 bits (64), Expect(2) = 3e-08
Identities = 13/21 (61%), Positives = 16/21 (76%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALY 3837
+R+ VG VTLQGNLDP +Y
Sbjct: 281 ARKRVGPNVTLQGNLDPQDMY 301
gi|19921920|ref|NP_610501.1| gi|8928075|sp|Q9V595|DCUP_DROME Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|7303877|gb|AAF58922.1|
Score = 53.9 bits (128), Expect(3) = 1e-17
Identities = 25/34 (73%), Positives = 25/34 (73%)
Frame = +3
Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
FP LKND LRAA GE D PVW MRQAGRYLP
Sbjct: 7 FPVLKNDNLLRAARGEVVDRVPVWVMRQAGRYLP 40
Score = 48.1 bits (113), Expect(2) = 2e-06
Identities = 33/132 (25%), Positives = 53/132 (40%)
Frame = +3
Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461
LQ+FES A HL + F ++ +PY++ + ++ RL + + VPM
Sbjct: 209 LQVFESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKAIPVVPMT-------------- 254
Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641
+FAK +L+E ++ GY+V+
Sbjct: 255 ---------------------------------------LFAKGAGHSLKEQSELGYDVI 275
Query: 3642 GLDWTVAPKKAR 3677
GLDWTV P +AR
Sbjct: 276 GLDWTVDPLEAR 287
Score = 43.9 bits (102), Expect = 0.027
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +3
Query: 4179 EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 4313
+E+ L +M+ FG RYIANLGHG+ P + V+AVHK
Sbjct: 310 DELRNLTTEMVHKFGKSRYIANLGHGITPQTPITSMEVLVEAVHK 354
Score = 41.6 bits (96), Expect(3) = 1e-17
Identities = 19/23 (82%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
+QPLRRF LDA+IIFSDILV+PQ
Sbjct: 66 MQPLRRFDLDASIIFSDILVIPQ 88
Score = 39.3 bits (90), Expect(3) = 1e-17
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EF+E R DFF+ CR+PE CE+T+Q
Sbjct: 41 EFQELRKHHDFFTVCRTPELACEVTMQ 67
Score = 29.3 bits (64), Expect(2) = 2e-06
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALY 3837
+R VG +TLQGNLDP +Y
Sbjct: 286 ARNLVGPNITLQGNLDPQDMY 306
gi|21430840|gb|AAM51098.1|
Score = 53.9 bits (128), Expect(3) = 1e-17
Identities = 25/34 (73%), Positives = 25/34 (73%)
Frame = +3
Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
FP LKND LRAA GE D PVW MRQAGRYLP
Sbjct: 7 FPVLKNDNLLRAARGEVVDRVPVWVMRQAGRYLP 40
Score = 46.6 bits (109), Expect(2) = 5e-06
Identities = 32/132 (24%), Positives = 53/132 (40%)
Frame = +3
Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461
LQ+FES A HL + F ++ +PY++ + ++ RL + + VP+
Sbjct: 209 LQVFESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKAIPVVPIT-------------- 254
Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641
+FAK +L+E ++ GY+V+
Sbjct: 255 ---------------------------------------LFAKGAGHSLKEQSELGYDVI 275
Query: 3642 GLDWTVAPKKAR 3677
GLDWTV P +AR
Sbjct: 276 GLDWTVDPLEAR 287
Score = 43.9 bits (102), Expect = 0.027
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +3
Query: 4179 EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 4313
+E+ L +M+ FG RYIANLGHG+ P + V+AVHK
Sbjct: 310 DELRNLTTEMVHKFGKSRYIANLGHGITPQTPITSMEVLVEAVHK 354
Score = 41.6 bits (96), Expect(3) = 1e-17
Identities = 19/23 (82%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
+QPLRRF LDA+IIFSDILV+PQ
Sbjct: 66 MQPLRRFDLDASIIFSDILVIPQ 88
Score = 39.3 bits (90), Expect(3) = 1e-17
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
EF+E R DFF+ CR+PE CE+T+Q
Sbjct: 41 EFQELRKHHDFFTVCRTPELACEVTMQ 67
Score = 29.3 bits (64), Expect(2) = 5e-06
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALY 3837
+R VG +TLQGNLDP +Y
Sbjct: 286 ARNLVGPNITLQGNLDPQDMY 306
gi|4140695|gb|AAD04167.1|
Score = 95.1 bits (235), Expect = 1e-17
Identities = 46/46 (100%), Positives = 46/46 (100%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 3416
ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM
Sbjct: 55 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 100
gi|3915203|sp|O18601|DCUP_DROVI Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|2317917|gb|AAB66372.1| uroprophyrinogen decarboxylase [Drosophila virilis]
Length = 386
Score = 103 bits (256), Expect = 4e-20
Identities = 65/161 (40%), Positives = 83/161 (51%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
QALG+ V M G GP P+P+ +DL+RL P+ S L YV AIT+ R +L GRVPL
Sbjct: 99 QALGLTVEMHAGVGPVLPQPICTPEDLKRLT-PDGALSRLTYVGDAITMMRHKLDGRVPL 157
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGF GAP W + G YM+EGGGS
Sbjct: 158 IGFTGAP---------------WTLMG------------------------YMIEGGGSK 178
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913
TM++AK WL P+ + L +LTD +V YL QV+AGAQ+
Sbjct: 179 TMSKAKAWLTNYPEDTKLFLILLTDVIVDYLEMQVIAGAQM 219
Score = 56.2 bits (134), Expect(2) = 1e-12
Identities = 26/36 (72%), Positives = 26/36 (72%)
Frame = +3
Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
Q FP LKND LRAA GE D PVW MRQAGRYLP
Sbjct: 16 QAFPPLKNDNLLRAARGEVVDRVPVWVMRQAGRYLP 51
Score = 48.9 bits (115), Expect(2) = 6e-07
Identities = 40/132 (30%), Positives = 58/132 (43%)
Frame = +3
Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461
LQ+FES A HL + F + PY+R + + RL + + VP+V + +L
Sbjct: 220 LQVFESSAEHLSKEEFLLGSEPYLRRIRDDLVDRLTKKVIPAVPLVSSYPNNIFTLL--- 276
Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641
L SL IIFAK +L+E ++ GY+V+
Sbjct: 277 --------------------------TYLISLL-----IIFAKGAGHSLKEQSELGYDVI 305
Query: 3642 GLDWTVAPKKAR 3677
GLDWTV P +AR
Sbjct: 306 GLDWTVDPVEAR 317
Score = 42.0 bits (97), Expect(2) = 1e-12
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQVRGPQKRERFMPSVCHLATCLLFPTA---TASL 2145
EF+E R DFF+ CR+PE CE+T+Q P +R S+ + L+ P A T +
Sbjct: 52 EFQELRKQHDFFTVCRTPELACEVTMQ---PLRRFDLDASII-FSDILVIPQALGLTVEM 107
Query: 2146 PSGCCHHFLRHPCCTP 2193
+G L P CTP
Sbjct: 108 HAG-VGPVLPQPICTP 122
Score = 41.6 bits (96), Expect = 0.13
Identities = 19/23 (82%), Positives = 22/23 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194
+QPLRRF LDA+IIFSDILV+PQ
Sbjct: 77 MQPLRRFDLDASIIFSDILVIPQ 99
Score = 35.4 bits (80), Expect = 9.7
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 4182 EIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVH 4310
E+ L +M+ G RYIAN+GHG+ P + V+A H
Sbjct: 341 ELRSLATEMVHKCGKSRYIANVGHGITPQTPITSMEVLVEAAH 383
Score = 30.0 bits (66), Expect(2) = 6e-07
Identities = 12/21 (57%), Positives = 16/21 (76%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALY 3837
+R VG +TLQGNLDP ++Y
Sbjct: 316 ARAVVGPNITLQGNLDPQSMY 336
gi|32418962|ref|XP_329959.1| hypothetical protein [Neurospora crassa]
gi|28926041|gb|EAA35030.1| hypothetical protein [Neurospora crassa]
Length = 390
Score = 101 bits (252), Expect = 1e-19
Identities = 63/164 (38%), Positives = 83/164 (50%), Gaps = 3/164 (1%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQD---LERLRDPEVVASELGYVFQAITLTRQRLAGR 2601
QA+GM V MV KGP FP PLR D E ++ VA EL YV++AITLTR++L GR
Sbjct: 109 QAMGMTVEMVDKKGPHFPNPLRSPSDGQYAELMKRDVDVAKELDYVYKAITLTRKKLDGR 168
Query: 2602 VPLIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGG 2781
VPL GF GAP W + + YMVEGG
Sbjct: 169 VPLFGFTGAP---------------WTL------------------------LCYMVEGG 189
Query: 2782 GSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913
G+ + K W+Y+ P+ + LL+ +++ V YL QV AGAQ+
Sbjct: 190 GTKLFKEVKTWIYKYPEETKALLQKISELCVEYLALQVKAGAQI 233
Score = 57.4 bits (137), Expect(2) = 3e-07
Identities = 43/149 (28%), Positives = 56/149 (37%), Gaps = 2/149 (1%)
Frame = +3
Query: 3234 SSLCVTYFSSPYPN*A--LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAP 3407
S LCV Y + A +Q+F+S AG L P F F+ PY+ +AK + RL+E GL P
Sbjct: 216 SELCVEYLALQVKAGAQIVQVFDSWAGELSPSSFKTFSQPYLTYIAKHLPLRLKEMGLEP 275
Query: 3408 VPMVRIGMG*VKVVLWSFQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFA 3587
VPMV +F
Sbjct: 276 VPMV-----------------------------------------------------VFP 282
Query: 3588 KDGHFALEELAQAGYEVVGLDWTVAPKKA 3674
K +AL+ GY VVGLDW P +A
Sbjct: 283 KGAWYALDAACDMGYNVVGLDWLHDPAEA 311
Score = 37.4 bits (85), Expect(3) = 9e-07
Identities = 19/30 (63%), Positives = 23/30 (76%), Gaps = 2/30 (6%)
Frame = +2
Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQVPTQT 2209
LQP+ R+ L+DAAIIFSDILV+PQ T
Sbjct: 85 LQPIERYAGLIDAAIIFSDILVIPQAMGMT 114
Score = 35.8 bits (81), Expect = 7.4
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDF---GPHR-YIANLGHGLYPDMDPEHVGAFVDA 4304
L G L E I ++V++M+ F G H+ +I NLGHG+ P ++P+ + F +
Sbjct: 322 LQGNADPGVLYGSHEAITKVVEEMVQGFDWHGRHKGWIVNLGHGITPFVNPDDLKFFFEE 381
Query: 4305 VHK 4313
+H+
Sbjct: 382 IHR 384
Score = 33.9 bits (76), Expect(3) = 9e-07
Identities = 13/27 (48%), Positives = 17/27 (62%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
E+ E + +DFF CR+PE LTLQ
Sbjct: 60 EYHEAKGGRDFFEVCRNPEIASTLTLQ 86
Score = 26.2 bits (56), Expect(3) = 9e-07
Identities = 16/34 (47%), Positives = 17/34 (50%)
Frame = +3
Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
FP LKND LRAA + AGRYLP
Sbjct: 34 FPPLKNDLLLRAARAP--------LILTAGRYLP 59
Score = 22.7 bits (47), Expect(2) = 3e-07
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = +1
Query: 3793 KTVTLQGNLDPCALYAS 3843
+ + LQGN DP LY S
Sbjct: 318 RPMVLQGNADPGVLYGS 334
gi|38110215|gb|EAA55971.1| hypothetical protein MG01622.4 [Magnaporthe grisea 70-15]
Length = 367
Score = 101 bits (251), Expect = 1e-19
Identities = 63/164 (38%), Positives = 85/164 (51%), Gaps = 3/164 (1%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQD---LERLRDPEVVASELGYVFQAITLTRQRLAGR 2601
QA+GM V MV KGP FP PL+ D E L V+ EL YV++AITLTR++L GR
Sbjct: 88 QAMGMVVEMVDKKGPHFPNPLQSPDDGQYAEVLARDVDVSKELDYVYKAITLTRKKLQGR 147
Query: 2602 VPLIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGG 2781
VPLIGF GAP W ++ YMVEGG
Sbjct: 148 VPLIGFCGAP---------------WTLF------------------------CYMVEGG 168
Query: 2782 GSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913
G+ Q+K+W+++ P+ S ++L+ + + V YL QV AGAQ+
Sbjct: 169 GTKLFIQSKKWIFRHPEESKKMLQKIAELCVEYLALQVQAGAQL 212
Score = 60.1 bits (144), Expect(2) = 5e-08
Identities = 42/149 (28%), Positives = 59/149 (39%), Gaps = 2/149 (1%)
Frame = +3
Query: 3234 SSLCVTYFSSPYPN*A--LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAP 3407
+ LCV Y + A +Q+F+S AG L P F +F+ PY+R +++ + RL+E L P
Sbjct: 195 AELCVEYLALQVQAGAQLVQVFDSWAGELSPASFEQFSAPYLRYISENLPKRLKELSLDP 254
Query: 3408 VPMVRIGMG*VKVVLWSFQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFA 3587
VPM+ +F
Sbjct: 255 VPMI-----------------------------------------------------VFP 261
Query: 3588 KDGHFALEELAQAGYEVVGLDWTVAPKKA 3674
K FALE+ GY VVGLDW +P KA
Sbjct: 262 KGAWFALEDCCAMGYNVVGLDWLYSPAKA 290
Score = 51.2 bits (121), Expect(3) = 2e-13
Identities = 20/34 (58%), Positives = 25/34 (73%)
Frame = +3
Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
F LKND +R AWG++ + P+W MRQAGRYLP
Sbjct: 5 FEPLKNDLVIRTAWGQKVERPPIWIMRQAGRYLP 38
Score = 37.0 bits (84), Expect(3) = 2e-13
Identities = 19/25 (76%), Positives = 22/25 (88%), Gaps = 2/25 (8%)
Frame = +2
Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQ 2194
LQP+ RF LLDA+IIFSDILV+PQ
Sbjct: 64 LQPIDRFDGLLDASIIFSDILVIPQ 88
Score = 32.7 bits (73), Expect(3) = 2e-13
Identities = 13/27 (48%), Positives = 16/27 (59%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
E+ E + +DFF CR PE LTLQ
Sbjct: 39 EYHEAKGNRDFFECCRDPEVASTLTLQ 65
Score = 22.7 bits (47), Expect(2) = 5e-08
Identities = 8/18 (44%), Positives = 12/18 (66%)
Frame = +1
Query: 3793 KTVTLQGNLDPCALYASE 3846
+ + LQGN DP LY ++
Sbjct: 297 REIVLQGNADPGVLYGTK 314
gi|21674849|ref|NP_662914.1| uroporphyrinogen decarboxylase [Chlorobium tepidum TLS]
gi|29611777|sp|Q8KAW2|DCUP_CHLTE Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|21648071|gb|AAM73256.1| uroporphyrinogen decarboxylase [Chlorobium tepidum TLS]
Length = 351
Score = 90.5 bits (223), Expect = 3e-16
Identities = 55/159 (34%), Positives = 81/159 (50%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
+A+GM V ++ KG P+R + D+++L DP++ +LGYV AI L ++ L RVPL
Sbjct: 80 EAMGMNVEIIETKGIKLTPPIRSQADIDKLIDPDI-DEKLGYVLDAIRLAKKELNDRVPL 138
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGF+GA W ++ TY VEGGGS
Sbjct: 139 IGFSGA---------------AWTLF------------------------TYAVEGGGSK 159
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGA 2907
AK+ +Y+ P+ +HQLL+ ++D + YLV QV AGA
Sbjct: 160 NYTWAKKMMYREPKMAHQLLQKISDCISAYLVKQVEAGA 198
Score = 45.8 bits (107), Expect(3) = 8e-10
Identities = 20/31 (64%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND F+RA + T TP+W MRQAGRYLP
Sbjct: 2 LKNDLFIRALKRQATPRTPIWVMRQAGRYLP 32
Score = 37.4 bits (85), Expect = 2.5
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
Frame = +3
Query: 4179 EEIGQLVKQMLDDFGPHR----YIANLGHGLYPDMDPEHVGAFVDAVHKHS 4319
E+I ++L FG H ++ NLGHG+ PD+DP ++ V+ V + S
Sbjct: 297 EKIKSEAAKVLKQFGQHNDHSGHVFNLGHGILPDVDPANLKCLVEFVKEES 347
Score = 33.9 bits (76), Expect(3) = 8e-10
Identities = 12/27 (44%), Positives = 18/27 (66%)
Frame = +1
Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055
E+R R DF + C++PE CE+T+Q
Sbjct: 33 EYRAVREKTDFLTLCKTPELACEVTIQ 59
Score = 32.3 bits (72), Expect(2) = 1.4
Identities = 15/34 (44%), Positives = 20/34 (58%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
I FAKD + L ++A G + VGL W + KAR
Sbjct: 241 IAFAKDMNTILSDIADCGADAVGLGWNIDIAKAR 274
Score = 28.5 bits (62), Expect(3) = 8e-10
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVV 2188
+QP+ +DAAIIFSDILVV
Sbjct: 58 IQPVDLMGVDAAIIFSDILVV 78
Score = 24.6 bits (52), Expect(2) = 1.4
Identities = 10/23 (43%), Positives = 15/23 (65%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYAS 3843
+R+ + V LQGN+DP LY +
Sbjct: 273 ARKELNDRVCLQGNMDPTVLYGT 295
gi|21232275|ref|NP_638192.1| uroporphyrinogen decarboxylase [Xanthomonas campestris pv. campestris
str. ATCC 33913]
gi|23813977|sp|Q8P6X1|DCUP_XANCP Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|21114039|gb|AAM42116.1| uroporphyrinogen decarboxylase [Xanthomonas campestris pv. campestris
str. ATCC 33913]
Length = 354
Score = 88.2 bits (217), Expect = 1e-15
Identities = 56/159 (35%), Positives = 76/159 (47%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+E+ V G+GP F P+R+ + RL P++ +EL YV A+ L R+ L G VPLI
Sbjct: 82 AMGLELYFVEGEGPKFRHPVRDADAIHRLGVPDM-ETELRYVMDAVRLIRRELDGAVPLI 140
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A YM+EGGGS
Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGGSKE 161
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
A+ K + PQ H LL +TDA++ YL Q AGAQ
Sbjct: 162 YARIKAMAFNAPQLLHHLLSTVTDAVIAYLSAQRAAGAQ 200
Score = 45.4 bits (106), Expect(3) = 1e-10
Identities = 21/31 (67%), Positives = 22/31 (70%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND LRA + D TPVW MRQAGRYLP
Sbjct: 2 LKNDRLLRALRRQPVDRTPVWLMRQAGRYLP 32
Score = 41.6 bits (96), Expect = 0.13
Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 2/51 (3%)
Frame = +3
Query: 4176 QEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322
+ E+G+ + G R ++ NLGHG+ PDM+P+HVG V+AV S+
Sbjct: 303 RSEVGKTLDSYAYGNGGSREGHVFNLGHGMSPDMNPDHVGVLVEAVQTLSK 353
Score = 38.5 bits (88), Expect = 1.1
Identities = 18/52 (34%), Positives = 33/52 (63%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434
ALQ+F++ G L P ++ +F+LPY+ +A++++ R +G P+V G G
Sbjct: 201 ALQVFDTWGGVLSPAMYREFSLPYLTRIAQELE---RGSGEERTPLVLFGKG 249
Score = 37.7 bits (86), Expect(3) = 1e-10
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL RF LDAAI+FSDIL +P
Sbjct: 59 LQPLERFPLDAAILFSDILTIP 80
Score = 31.2 bits (69), Expect(2) = 0.19
Identities = 12/29 (41%), Positives = 19/29 (65%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVA 3662
++F K + ELA +G E VG+DWT++
Sbjct: 244 VLFGKGNGAYVSELAASGAEAVGVDWTIS 272
Score = 28.9 bits (63), Expect(2) = 0.19
Identities = 14/27 (51%), Positives = 15/27 (55%)
Frame = +1
Query: 3781 ECVGKTVTLQGNLDPCALYASEVTARA 3861
E G V LQGNLDP LY S R+
Sbjct: 278 ERAGGRVALQGNLDPATLYGSPDAIRS 304
Score = 28.1 bits (61), Expect(3) = 1e-10
Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A F ++P+ CE+TLQ
Sbjct: 33 EYRATRARAGSFLGMAKNPDIACEVTLQ 60
gi|21243740|ref|NP_643322.1| uroporphyrinogen decarboxylase [Xanthomonas axonopodis pv. citri str.
306]
gi|23813978|sp|Q8PI85|DCUP_XANAC Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|21109326|gb|AAM37858.1| uroporphyrinogen decarboxylase [Xanthomonas axonopodis pv. citri str.
306]
Length = 354
Score = 86.7 bits (213), Expect = 4e-15
Identities = 54/159 (33%), Positives = 76/159 (47%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+E+ V G+GP F P+R+ + RL P++ +EL YV A+ + R+ L G VPLI
Sbjct: 82 AMGLELYFVEGEGPKFRHPVRDAAAIHRLGVPDM-ETELRYVMDAVRVIRRELDGSVPLI 140
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A YM+EGGGS
Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGGSKE 161
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
A+ K + P+ H LL +TDA++ YL Q AGAQ
Sbjct: 162 YARIKAMAFNAPELLHHLLNTVTDAVIAYLAAQRAAGAQ 200
Score = 45.1 bits (105), Expect(3) = 1e-10
Identities = 21/31 (67%), Positives = 22/31 (70%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND LRA + D TPVW MRQAGRYLP
Sbjct: 2 LKNDRLLRALNRQPVDRTPVWLMRQAGRYLP 32
Score = 43.5 bits (101), Expect = 0.035
Identities = 21/49 (42%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
Frame = +3
Query: 4182 EIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322
E+G+ + G R ++ NLGHG+ PDM+PEHVG V+AV S+
Sbjct: 305 EVGKTLDSYAQGNGGSREGHVFNLGHGMSPDMNPEHVGVLVEAVQTLSK 353
Score = 38.5 bits (88), Expect = 1.1
Identities = 18/52 (34%), Positives = 32/52 (61%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434
ALQ+F++ G L P ++ +F+LPY+ +A++++ R G P+V G G
Sbjct: 201 ALQVFDTWGGVLSPAMYREFSLPYLTRIARELE---RGDGAERTPLVLFGKG 249
Score = 38.1 bits (87), Expect(3) = 1e-10
Identities = 17/22 (77%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL+RF LDAAI+FSDIL +P
Sbjct: 59 LQPLQRFPLDAAILFSDILTIP 80
Score = 28.1 bits (61), Expect(3) = 1e-10
Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A F ++P+ CE+TLQ
Sbjct: 33 EYRATRARAGSFLGMAKNPDIACEVTLQ 60
gi|28872231|ref|NP_794850.1| uroporphyrinogen decarboxylase [Pseudomonas syringae pv. tomato str.
DC3000]
gi|38257459|sp|Q87V23|DCUP_PSESM Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|28855485|gb|AAO58545.1| uroporphyrinogen decarboxylase [Pseudomonas syringae pv. tomato str.
DC3000]
Length = 354
Score = 85.1 bits (209), Expect = 1e-14
Identities = 56/159 (35%), Positives = 75/159 (47%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F + + D+E L P+ +LGYV A++ R+ L GRVPLI
Sbjct: 84 AMGLGLYFETGEGPRFKKTVSTLADIEALPIPDA-QQDLGYVMDAVSTIRRELNGRVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GFAG+P W A TYMVEGG S
Sbjct: 143 GFAGSP--WTLA-------------------------------------TYMVEGGSSKD 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
++K LY PQA H LL L ++ YL GQ++AGAQ
Sbjct: 164 FRKSKAMLYDNPQAMHLLLDKLAQSVTSYLNGQILAGAQ 202
Score = 48.5 bits (114), Expect(3) = 1e-12
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA + D TPVW MRQAGRYLP
Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 45.1 bits (105), Expect = 0.012
Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G + L E I Q V ++L +G ++ NLGHG+ P++DP + GAF++AVH+
Sbjct: 288 LQGNMDPTVLYARPEAIRQEVARILASYGSGTGHVFNLGHGITPEVDPANAGAFINAVHE 347
Query: 4314 HSRLLRQ 4334
S Q
Sbjct: 348 LSAQYHQ 354
Score = 37.7 bits (86), Expect = 1.9
Identities = 30/105 (28%), Positives = 42/105 (40%)
Frame = +1
Query: 3694 EALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCALYASEVTARAPLCV 3873
+ L L W C +GE +R+ VG V+LQGN+DP LYA R +
Sbjct: 265 DTLGLDWTCDIGE--------------ARQRVGNKVSLQGNMDPTVLYARPEAIRQEVAR 310
Query: 3874 LLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008
+L G VFN+ + + P G F+ VH
Sbjct: 311 ILASYGSGTG------HVFNLGHGITPE---VDPANAGAFINAVH 346
Score = 35.8 bits (81), Expect(3) = 1e-12
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL R+ LDAAI+FSDIL +P
Sbjct: 61 LQPLDRYPLDAAILFSDILTIP 82
Score = 33.5 bits (75), Expect(3) = 1e-12
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R +RA A DF S C++P+ CE+TLQ
Sbjct: 35 EYRASRASAGDFMSLCKNPQFACEVTLQ 62
gi|16123871|ref|NP_407184.1| uroporphyrinogen decarboxylase [Yersinia pestis]
gi|22124411|ref|NP_667834.1| uroporphyrinogen decarboxylase [Yersinia pestis KIM]
gi|23813999|sp|Q8ZAQ7|DCUP_YERPE Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|25291020|pir||AF0454 uroporphyrinogen decarboxylase (EC 4.1.1.37) [imported] - Yersinia
pestis (strain CO92)
gi|15981650|emb|CAC93202.1| uroporphyrinogen decarboxylase [Yersinia pestis CO92]
gi|21957194|gb|AAM84085.1| uroporphyrinogen decarboxylase [Yersinia pestis KIM]
Length = 355
Score = 84.7 bits (208), Expect = 1e-14
Identities = 55/159 (34%), Positives = 74/159 (46%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F P+ D+E+L P+ ELGYV A+ R+ LAG VPLI
Sbjct: 84 AMGLGLYFETGEGPRFQSPITCRADVEKLPIPDP-EQELGYVMNAVRTIRRELAGSVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K+ +Y PQ H LL L D+++ YL Q+ AGAQ
Sbjct: 164 FTKLKKMMYAEPQTLHLLLDKLADSVILYLNAQIKAGAQ 202
Score = 50.4 bits (119), Expect = 3e-04
Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G S L P I Q V +L FG ++ NLGHG++ D+ P H GAFV+AVH
Sbjct: 288 LQGNMDPSVLYAPPARIEQEVSTILASFGQGEGHVFNLGHGIHQDVPPAHAGAFVNAVHA 347
Query: 4314 HSRLLRQ 4334
SR Q
Sbjct: 348 LSRPYHQ 354
Score = 49.3 bits (116), Expect(3) = 8e-13
Identities = 22/32 (68%), Positives = 24/32 (75%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA + D TPVW MRQAGRYLP
Sbjct: 3 ELKNDRYLRALLRQPVDMTPVWMMRQAGRYLP 34
Score = 37.7 bits (86), Expect(3) = 8e-13
Identities = 16/22 (72%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
+QPLRR+ LDAAI+FSDIL +P
Sbjct: 61 MQPLRRYPLDAAILFSDILTIP 82
Score = 31.6 bits (70), Expect(3) = 8e-13
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E++ TRA A DF S C++ E CE+T+Q
Sbjct: 35 EYKATRAIAGDFMSLCKNAELACEVTMQ 62
Score = 31.2 bits (69), Expect(2) = 0.19
Identities = 26/78 (33%), Positives = 31/78 (39%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954
+R VG V LQGN+DP LYA + +L G VFN L
Sbjct: 278 ARRRVGDKVALQGNMDPSVLYAPPARIEQEVSTILASFGQGEG------HVFN--LGHGI 329
Query: 3955 HLYTISPRKTGLFVAVVH 4008
H + P G FV VH
Sbjct: 330 H-QDVPPAHAGAFVNAVH 346
Score = 28.9 bits (63), Expect(2) = 0.19
Identities = 14/33 (42%), Positives = 18/33 (54%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
+F K G LE +A G + +GLDWT AR
Sbjct: 247 LFTKGGGPWLEAMAATGCDALGLDWTTDIADAR 279
gi|33598623|ref|NP_886266.1| uroporphyrinogen decarboxylase [Bordetella parapertussis]
gi|33574752|emb|CAE39411.1| uroporphyrinogen decarboxylase [Bordetella parapertussis]
Length = 358
Score = 84.3 bits (207), Expect = 2e-14
Identities = 55/159 (34%), Positives = 73/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + PG+GP F P+R+E D+ +L P++ L YVF A+ R+ L GRVPLI
Sbjct: 86 AMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDM--DSLRYVFDAVRTIRRELDGRVPLI 143
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GFAG+P W + YMVEG GS
Sbjct: 144 GFAGSP---------------WTI------------------------ACYMVEGRGSDD 164
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K LY RP H++L I +A YL Q+ AGAQ
Sbjct: 165 YRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQ 203
Score = 50.1 bits (118), Expect(3) = 6e-11
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA E YTP+W MRQAGRYLP
Sbjct: 6 LKNDVFLRALLREPVPYTPIWLMRQAGRYLP 36
Score = 37.0 bits (84), Expect = 3.3
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = +3
Query: 4200 KQMLDDFGP---HRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLL 4328
++ LD FGP ++ NLGHG+ PE V VD VH +SR L
Sbjct: 310 RRTLDAFGPVGKGGHVFNLGHGISQYSPPEVVSELVDEVHTYSRAL 355
Score = 36.6 bits (83), Expect(3) = 6e-11
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL R+ LDAAI+FSDIL VP
Sbjct: 63 LQPLARYPLDAAILFSDILTVP 84
Score = 36.2 bits (82), Expect = 5.7
Identities = 18/34 (52%), Positives = 22/34 (64%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
I+F+K G LEE+A G + VGLDWTV AR
Sbjct: 247 IVFSKGGGQWLEEIAACGCDAVGLDWTVNLGTAR 280
Score = 25.4 bits (54), Expect(3) = 6e-11
Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+ TRA A F ++P+ CE+TLQ
Sbjct: 37 EYNATRARAGSFMGLAQNPDYACEVTLQ 64
gi|33603574|ref|NP_891134.1| uroporphyrinogen decarboxylase [Bordetella bronchiseptica]
gi|33577699|emb|CAE34964.1| uroporphyrinogen decarboxylase [Bordetella bronchiseptica]
Length = 358
Score = 84.3 bits (207), Expect = 2e-14
Identities = 55/159 (34%), Positives = 73/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + PG+GP F P+R+E D+ +L P++ L YVF A+ R+ L GRVPLI
Sbjct: 86 AMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDM--DSLRYVFDAVRTIRRELDGRVPLI 143
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GFAG+P W + YMVEG GS
Sbjct: 144 GFAGSP---------------WTI------------------------ACYMVEGRGSDD 164
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K LY RP H++L I +A YL Q+ AGAQ
Sbjct: 165 YRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQ 203
Score = 50.1 bits (118), Expect(3) = 6e-11
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA E YTP+W MRQAGRYLP
Sbjct: 6 LKNDVFLRALLREPVPYTPIWLMRQAGRYLP 36
Score = 37.0 bits (84), Expect = 3.3
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = +3
Query: 4200 KQMLDDFGP---HRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLL 4328
++ LD FGP ++ NLGHG+ PE V VD VH +SR L
Sbjct: 310 RRTLDAFGPVGKGGHVFNLGHGISQYSPPEVVSELVDEVHTYSRAL 355
Score = 36.6 bits (83), Expect(3) = 6e-11
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL R+ LDAAI+FSDIL VP
Sbjct: 63 LQPLARYPLDAAILFSDILTVP 84
Score = 35.8 bits (81), Expect = 7.4
Identities = 18/34 (52%), Positives = 21/34 (61%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
I+F K G LEE+A G + VGLDWTV AR
Sbjct: 247 IVFTKGGGQWLEEIAACGCDAVGLDWTVNLGTAR 280
Score = 25.4 bits (54), Expect(3) = 6e-11
Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+ TRA A F ++P+ CE+TLQ
Sbjct: 37 EYNATRARAGSFMGLAQNPDYACEVTLQ 64
gi|23469744|ref|ZP_00125078.1| COG0407: Uroporphyrinogen-III decarboxylase [Pseudomonas syringae pv.
syringae B728a]
Length = 354
Score = 84.0 bits (206), Expect = 2e-14
Identities = 56/159 (35%), Positives = 74/159 (46%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G + G+GP F + + D+E L P+ +LGYV A++ R+ L GRVPLI
Sbjct: 84 AMGQGLYFETGEGPRFRKTVSTLADIEALPIPDA-QQDLGYVMDAVSTIRRELNGRVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GFAG+P W A TYMVEGG S
Sbjct: 143 GFAGSP--WTLA-------------------------------------TYMVEGGSSKD 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
++K LY PQA H LL L ++ YL GQ++AGAQ
Sbjct: 164 FRKSKAMLYDNPQAMHLLLDKLAQSVTSYLNGQILAGAQ 202
Score = 48.5 bits (114), Expect(3) = 1e-12
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA + D TPVW MRQAGRYLP
Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 44.7 bits (104), Expect = 0.016
Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G + L E I Q V ++L +G ++ NLGHG+ P++DP + GAF++AVH+
Sbjct: 288 LQGNMDPTVLYARPEAIRQEVARILASYGSGTGHVFNLGHGITPEVDPANAGAFINAVHE 347
Query: 4314 HS 4319
S
Sbjct: 348 LS 349
Score = 37.7 bits (86), Expect = 1.9
Identities = 30/105 (28%), Positives = 42/105 (40%)
Frame = +1
Query: 3694 EALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCALYASEVTARAPLCV 3873
+ L L W C +GE +R+ VG V+LQGN+DP LYA R +
Sbjct: 265 DTLGLDWTCDIGE--------------ARQRVGSKVSLQGNMDPTVLYARPEAIRQEVAR 310
Query: 3874 LLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008
+L G VFN+ + + P G F+ VH
Sbjct: 311 ILASYGSGTG------HVFNLGHGITPE---VDPANAGAFINAVH 346
Score = 36.2 bits (82), Expect(3) = 1e-12
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVPQVPTQ 2206
LQPL R+ LDAAI+FSDIL +P Q
Sbjct: 61 LQPLDRYPLDAAILFSDILTIPDAMGQ 87
Score = 33.5 bits (75), Expect(3) = 1e-12
Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R +RA A DF S C++P+ CE+TLQ
Sbjct: 35 EYRASRASAGDFMSLCKNPQFACEVTLQ 62
gi|33594189|ref|NP_881833.1| uroporphyrinogen decarboxylase [Bordetella pertussis]
gi|33564264|emb|CAE43556.1| uroporphyrinogen decarboxylase [Bordetella pertussis]
Length = 358
Score = 82.8 bits (203), Expect = 5e-14
Identities = 54/159 (33%), Positives = 72/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + PG+GP F P+R+E D+ +L P++ L YVF A+ R+ L GRVPLI
Sbjct: 86 AMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDM--DSLRYVFDAVRTIRRELDGRVPLI 143
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GFAG+P W + YM EG GS
Sbjct: 144 GFAGSP---------------WTI------------------------ACYMAEGRGSDD 164
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K LY RP H++L I +A YL Q+ AGAQ
Sbjct: 165 YRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQ 203
Score = 50.1 bits (118), Expect(3) = 6e-11
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA E YTP+W MRQAGRYLP
Sbjct: 6 LKNDVFLRALLREPVPYTPIWLMRQAGRYLP 36
Score = 37.0 bits (84), Expect = 3.3
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Frame = +3
Query: 4200 KQMLDDFGP---HRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLL 4328
++ LD FGP ++ NLGHG+ PE V VD VH +SR L
Sbjct: 310 RRTLDAFGPVGKGGHVFNLGHGISQYSPPEVVSELVDEVHTYSRAL 355
Score = 36.6 bits (83), Expect(3) = 6e-11
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL R+ LDAAI+FSDIL VP
Sbjct: 63 LQPLARYPLDAAILFSDILTVP 84
Score = 35.8 bits (81), Expect = 7.4
Identities = 18/34 (52%), Positives = 21/34 (61%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
I+F K G LEE+A G + VGLDWTV AR
Sbjct: 247 IVFTKGGGQWLEEIAACGCDAVGLDWTVNLGAAR 280
Score = 25.4 bits (54), Expect(3) = 6e-11
Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+ TRA A F ++P+ CE+TLQ
Sbjct: 37 EYNATRARAGSFMGLAQNPDYACEVTLQ 64
gi|23104868|ref|ZP_00091328.1| COG0407: Uroporphyrinogen-III decarboxylase [Azotobacter vinelandii]
Length = 355
Score = 82.8 bits (203), Expect = 5e-14
Identities = 56/159 (35%), Positives = 74/159 (46%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F + + D+E L P+ +LGYV A+ R+ L GRVPLI
Sbjct: 85 AMGLGLYFETGEGPRFRKVVSSPADIEALPVPDP-ERDLGYVMAAVRTIRRELNGRVPLI 143
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 144 GFSGSP--WTLA-------------------------------------TYMVEGGSSKD 164
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
++K LY PQA H LL L A+ YL GQ++AGAQ
Sbjct: 165 FRKSKAMLYDNPQAMHALLDKLARAVTAYLNGQILAGAQ 203
Score = 48.5 bits (114), Expect(3) = 5e-12
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA + D TPVW MRQAGRYLP
Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 42.4 bits (98), Expect = 0.079
Identities = 16/29 (55%), Positives = 23/29 (79%)
Frame = +3
Query: 4233 YIANLGHGLYPDMDPEHVGAFVDAVHKHS 4319
++ NLGHG+ P++DP H GAF +AVH+ S
Sbjct: 322 HVFNLGHGITPEVDPAHAGAFFEAVHELS 350
Score = 39.7 bits (91), Expect = 0.51
Identities = 35/119 (29%), Positives = 46/119 (38%)
Frame = +1
Query: 3652 GQWPQRKPGKPWKGEALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCA 3831
G W + G EAL L W C +G+ +R VG V LQGN+DP
Sbjct: 254 GLWLEAMAGSG--AEALGLDWTCDIGD--------------ARARVGGKVALQGNMDPSV 297
Query: 3832 LYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008
LYA+ RA + +L G VFN+ + + P G F VH
Sbjct: 298 LYANPAAIRAEVARILARYGAGSG------HVFNLGHGITPE---VDPAHAGAFFEAVH 347
Score = 35.4 bits (80), Expect(3) = 5e-12
Identities = 17/28 (60%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A DF S C +PE CE+TLQ
Sbjct: 35 EYRATRAKAGDFMSLCMNPELACEVTLQ 62
Score = 32.0 bits (71), Expect(3) = 5e-12
Identities = 17/23 (73%), Positives = 19/23 (82%), Gaps = 1/23 (4%)
Frame = +2
Query: 2126 LQPLRRF-LLDAAIIFSDILVVP 2191
LQPL R+ LDAAI+FSDIL VP
Sbjct: 61 LQPLDRYPQLDAAILFSDILTVP 83
gi|22994377|ref|ZP_00038883.1| COG0407: Uroporphyrinogen-III decarboxylase [Xylella fastidiosa
Dixon]
Length = 354
Score = 82.8 bits (203), Expect = 5e-14
Identities = 52/159 (32%), Positives = 74/159 (46%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+E+ + G+GP +P+R+ + +L P++ +EL YV A+ L R+ L VPLI
Sbjct: 82 AMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDM-ETELRYVMDAVRLIRKELDNSVPLI 140
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A YM+EGGGS
Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGGSKE 161
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
A K + P HQLL +TDA++ YL Q AGAQ
Sbjct: 162 YAHIKAMAFNAPDVLHQLLNTVTDAVISYLAAQRAAGAQ 200
Score = 45.1 bits (105), Expect = 0.012
Identities = 20/31 (64%), Positives = 22/31 (70%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND LRA + D TP+W MRQAGRYLP
Sbjct: 2 LKNDRLLRALRRDTVDRTPIWLMRQAGRYLP 32
Score = 42.0 bits (97), Expect = 0.10
Identities = 17/30 (56%), Positives = 23/30 (76%)
Frame = +3
Query: 4233 YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322
++ NLGHG+ P MDP+HV A V+AV + SR
Sbjct: 324 HVFNLGHGMTPGMDPDHVSALVEAVQRLSR 353
Score = 40.0 bits (92), Expect(2) = 0.002
Identities = 18/22 (81%), Positives = 21/22 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRRF LDAAI+FSDIL++P
Sbjct: 59 LQPLRRFPLDAAILFSDILMIP 80
Score = 38.5 bits (88), Expect = 1.1
Identities = 18/52 (34%), Positives = 31/52 (59%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434
ALQ+F++ G L P ++ F+LPY+ +A++++ R G P+V G G
Sbjct: 201 ALQVFDTWGGILSPTMYRTFSLPYLTRIARELE---RGTGTEHTPLVLFGKG 249
Score = 26.6 bits (57), Expect(2) = 0.002
Identities = 14/45 (31%), Positives = 20/45 (44%)
Frame = +1
Query: 1921 RGGLWRASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQ 2055
R +W + P Y R+ A F ++PE CE+TLQ
Sbjct: 18 RTPIWLMRQAGRYLPEYRAARQH--AGSFLKMAKTPELACEITLQ 60
gi|23138367|ref|ZP_00120028.1| COG0407: Uroporphyrinogen-III decarboxylase [Cytophaga hutchinsonii]
Length = 344
Score = 82.4 bits (202), Expect = 7e-14
Identities = 54/159 (33%), Positives = 74/159 (46%)
Frame = +1
Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610
+A+G+ M KGP FP+ + D++ L + A L YV+ AI L + L GRVPL
Sbjct: 82 EAMGLPYEMQESKGPFFPKVITSAADIDALLATDA-ADHLTYVYDAIELAVKELNGRVPL 140
Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790
IGFAGAP + YM+EG GS
Sbjct: 141 IGFAGAP---------------------------------------FTILAYMIEGQGSK 161
Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGA 2907
T ++A+R+LY P +H+LL +T A + YL QV AGA
Sbjct: 162 TFSKARRFLYTEPVLAHRLLEKITLATIAYLKRQVQAGA 200
Score = 57.0 bits (136), Expect = 3e-06
Identities = 28/49 (57%), Positives = 33/49 (67%)
Frame = +3
Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAV 4307
AL + +E+I K+MLD FG +IANLGHGLYPD D V FVDAV
Sbjct: 289 ALYLSEEQIRVKAKEMLDAFGTQSHIANLGHGLYPDTDKTKVKCFVDAV 337
Score = 44.3 bits (103), Expect = 0.021
Identities = 20/32 (62%), Positives = 23/32 (71%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
+ +ND LRAA GE + TPVW MRQAGR LP
Sbjct: 2 QYQNDLILRAARGEAVERTPVWLMRQAGRILP 33
Score = 37.0 bits (84), Expect(2) = 0.053
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTAR 3858
S++ +G TLQGN+DPCALY SE R
Sbjct: 271 SKKIIGPHKTLQGNMDPCALYLSEEQIR 298
Score = 25.0 bits (53), Expect(2) = 0.053
Identities = 10/27 (37%), Positives = 14/27 (51%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTV 3659
+F+K F E+ E VGLDW +
Sbjct: 240 VFSKGAFFVREDFNNFPCETVGLDWNM 266
gi|15603599|ref|NP_246673.1| UroD [Pasteurella multocida]
gi|13431433|sp|P57964|DCUP_PASMU Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|12722148|gb|AAK03818.1| UroD [Pasteurella multocida]
Length = 354
Score = 82.4 bits (202), Expect = 7e-14
Identities = 54/159 (33%), Positives = 74/159 (46%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ ++ G+GP F P+ ++ ++ L P+ EL YV A+ R+ L G VPLI
Sbjct: 84 AMGLGLSFGVGEGPKFAHPIETQRAVQNLPIPDP-EGELQYVMNAVRTIRRELKGEVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K+ LY PQ HQLL L DA++ YL Q+ AGAQ
Sbjct: 164 FTKIKKMLYADPQLLHQLLDKLADAVILYLNAQIKAGAQ 202
Score = 47.4 bits (111), Expect(3) = 2e-13
Identities = 21/31 (67%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND +L+A E D TPVW MRQAGRYLP
Sbjct: 4 LKNDRYLKALLREPVDMTPVWMMRQAGRYLP 34
Score = 39.7 bits (91), Expect = 0.51
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G S L I Q V+ +L DFG ++ NLGHG++ D+ + FV+A+H+
Sbjct: 288 LQGNMDPSVLYASPARIEQEVRSILADFGEGSGHVFNLGHGIHQDVPEQSPAVFVNAIHQ 347
Query: 4314 HSR 4322
S+
Sbjct: 348 FSQ 350
Score = 38.5 bits (88), Expect(3) = 2e-13
Identities = 17/22 (77%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRR+ LDAAI+FSDIL +P
Sbjct: 61 LQPLRRYPLDAAILFSDILTIP 82
Score = 34.7 bits (78), Expect(3) = 2e-13
Identities = 17/28 (60%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A DF S CR+ E CE+TLQ
Sbjct: 35 EYRATRAVAGDFMSLCRNAELACEVTLQ 62
Score = 32.3 bits (72), Expect(2) = 0.041
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTV--APKKAR 3677
+F K G LE +A+ G + +G+DWTV A KAR
Sbjct: 247 LFTKGGGMWLEAMAETGCDALGVDWTVNLAQAKAR 281
Score = 30.0 bits (66), Expect(2) = 0.041
Identities = 13/19 (68%), Positives = 14/19 (73%)
Frame = +1
Query: 3787 VGKTVTLQGNLDPCALYAS 3843
VG V LQGN+DP LYAS
Sbjct: 282 VGHKVALQGNMDPSVLYAS 300
gi|28899690|ref|NP_799295.1| uroporphyrinogen decarboxylase [Vibrio parahaemolyticus RIMD 2210633]
gi|31340033|sp|Q87KR0|DCUP_VIBPA Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|28807942|dbj|BAC61179.1| uroporphyrinogen decarboxylase [Vibrio parahaemolyticus]
Length = 355
Score = 79.7 bits (195), Expect = 4e-13
Identities = 55/161 (34%), Positives = 74/161 (45%), Gaps = 2/161 (1%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLER--LRDPEVVASELGYVFQAITLTRQRLAGRVP 2607
A+G+ + G+GP F P+ + D+E+ L DPE EL YV A+ R+ L G VP
Sbjct: 84 AMGLGLRFAAGEGPVFDNPITCKADVEKIGLPDPE---GELQYVMNAVRQIRKDLNGDVP 140
Query: 2608 LIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGS 2787
LIGF+G+P W A TYMVEGG S
Sbjct: 141 LIGFSGSP--WTLA-------------------------------------TYMVEGGSS 161
Query: 2788 STMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K+ +Y PQ H LL L D+++ YL Q+ AGAQ
Sbjct: 162 KAFTKIKKMMYAEPQTLHLLLDKLADSVIDYLNAQIKAGAQ 202
Score = 53.5 bits (127), Expect(3) = 1e-13
Identities = 24/32 (75%), Positives = 25/32 (78%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA E DYTPVW MRQAGRYLP
Sbjct: 3 ELKNDRYLRALLKEPVDYTPVWMMRQAGRYLP 34
Score = 44.3 bits (103), Expect = 0.021
Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 2/64 (3%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVH 4310
L G S L E I + V +L+ FG ++ NLGHG++ D+ PE+ G FV+AVH
Sbjct: 288 LQGNMDPSMLYASPERIREEVAGILEGFGDAGTGHVFNLGHGIHLDVPPENAGVFVEAVH 347
Query: 4311 KHSR 4322
+ S+
Sbjct: 348 ELSK 351
Score = 39.7 bits (91), Expect(3) = 1e-13
Identities = 18/22 (81%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRRF LDAAI+FSDIL +P
Sbjct: 61 LQPLRRFPLDAAILFSDILTIP 82
Score = 35.0 bits (79), Expect(2) = 9e-04
Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWT--VAPKKAR 3677
+F K+G LE++A G + VGLDWT +A KAR
Sbjct: 247 LFTKNGGMWLEQIAATGCDAVGLDWTINIADAKAR 281
Score = 33.1 bits (74), Expect(2) = 9e-04
Identities = 27/74 (36%), Positives = 33/74 (44%)
Frame = +1
Query: 3787 VGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYT 3966
+G V LQGN+DP LYAS R + +L A VFN L HL
Sbjct: 282 IGDKVALQGNMDPSMLYASPERIREEVAGILEGFGDAG-----TGHVFN--LGHGIHL-D 333
Query: 3967 ISPRKTGLFVAVVH 4008
+ P G+FV VH
Sbjct: 334 VPPENAGVFVEAVH 347
Score = 28.5 bits (62), Expect(3) = 1e-13
Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E++ TRA A DF S C++ E E+TLQ
Sbjct: 35 EYKATRAQAGDFMSLCKNAELASEVTLQ 62
gi|26991750|ref|NP_747175.1| uroporphyrinogen decarboxylase [Pseudomonas putida KT2440]
gi|38257478|sp|Q88CV6|DCUP_PSEPK Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|24986857|gb|AAN70639.1| uroporphyrinogen decarboxylase [Pseudomonas putida KT2440]
Length = 354
Score = 81.3 bits (199), Expect = 2e-13
Identities = 54/159 (33%), Positives = 73/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F + + D+E L P+ +LGYV A++ R+ L GRVPLI
Sbjct: 84 AMGLGLYFETGEGPRFKKVISTPADIEALPVPDP-QKDLGYVMDAVSTIRRELNGRVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKD 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K Y PQA H LL L ++ YL GQ++AGAQ
Sbjct: 164 FRKTKAMAYDNPQALHLLLDKLAQSVTSYLNGQILAGAQ 202
Score = 48.5 bits (114), Expect = 0.001
Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G + L E I + V ++L +G ++ NLGHG+ P++DPEH GAF++AVH+
Sbjct: 288 LQGNMDPTVLYAKPEAIRKEVARILASYGHGTGHVFNLGHGITPEVDPEHAGAFINAVHE 347
Query: 4314 HSRLLRQ 4334
S Q
Sbjct: 348 LSAQYHQ 354
Score = 48.5 bits (114), Expect(3) = 3e-12
Identities = 22/31 (70%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND FLRA + D TPVW MRQAGRYLP
Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 37.0 bits (84), Expect = 3.3
Identities = 30/105 (28%), Positives = 41/105 (39%)
Frame = +1
Query: 3694 EALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCALYASEVTARAPLCV 3873
+AL L W C +G+ +R VG V LQGN+DP LYA R +
Sbjct: 265 DALGLDWTCEIGD--------------ARRRVGDKVALQGNMDPTVLYAKPEAIRKEVAR 310
Query: 3874 LLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008
+L G VFN+ + + P G F+ VH
Sbjct: 311 ILASYGHGTG------HVFNLGHGITPE---VDPEHAGAFINAVH 346
Score = 35.8 bits (81), Expect(3) = 3e-12
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL R+ LDAAI+FSDIL +P
Sbjct: 61 LQPLDRYPLDAAILFSDILTIP 82
Score = 35.4 bits (80), Expect = 9.7
Identities = 16/34 (47%), Positives = 22/34 (64%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
I+F K+G LE +A+AG + +GLDWT AR
Sbjct: 246 ILFTKNGGLWLESIAEAGADALGLDWTCEIGDAR 279
Score = 32.3 bits (72), Expect(3) = 3e-12
Identities = 15/28 (53%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R +RA A DF S C +P+ CE+TLQ
Sbjct: 35 EYRASRAKAGDFMSLCMNPQFACEVTLQ 62
gi|409791|gb|AAC43095.1| uroporphyrinogen decarboxylase
Length = 354
Score = 78.2 bits (191), Expect = 1e-12
Identities = 53/159 (33%), Positives = 72/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F P+ + D+++L P+ ELGYV A+ R+ L G VPLI
Sbjct: 84 AMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDP-EDELGYVMNAVRTIRRELKGEVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K+ +Y PQA H LL L ++ YL Q+ AGAQ
Sbjct: 164 FTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQ 202
Score = 49.7 bits (117), Expect(3) = 2e-13
Identities = 22/32 (68%), Positives = 24/32 (75%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA + D TPVW MRQAGRYLP
Sbjct: 3 ELKNDRYLRALLXQPVDVTPVWMMRQAGRYLP 34
Score = 47.8 bits (112), Expect = 0.002
Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G S L P I + V +L FG ++ NLGHG++ D+ PEH G FV+AVH+
Sbjct: 288 LQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHR 347
Query: 4314 HS 4319
S
Sbjct: 348 LS 349
Score = 38.9 bits (89), Expect(3) = 2e-13
Identities = 18/22 (81%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRR+ LDAAI+FSDIL VP
Sbjct: 61 LQPLRRYPLDAAILFSDILTVP 82
Score = 32.3 bits (72), Expect(3) = 2e-13
Identities = 15/28 (53%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E++ TRA A DF S C++ E CE+TLQ
Sbjct: 35 EYKATRAQAGDFMSLCKNAELACEVTLQ 62
Score = 32.0 bits (71), Expect(2) = 0.041
Identities = 26/78 (33%), Positives = 32/78 (41%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954
+R VG V LQGN+DP LYA + +L G VFN L
Sbjct: 278 ARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEG------HVFN--LGHGI 329
Query: 3955 HLYTISPRKTGLFVAVVH 4008
H + P G+FV VH
Sbjct: 330 H-QDVPPEHAGVFVEAVH 346
Score = 30.4 bits (67), Expect(2) = 0.041
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
+F K G LE +A+ G + +GLDWT AR
Sbjct: 247 LFTKGGGQWLEAMAETGCDALGLDWTTDIADAR 279
gi|34496577|ref|NP_900792.1| uroporphyrinogen decarboxylase [Chromobacterium violaceum ATCC 12472]
gi|34102431|gb|AAQ58797.1| uroporphyrinogen decarboxylase [Chromobacterium violaceum ATCC 12472]
Length = 331
Score = 80.9 bits (198), Expect = 2e-13
Identities = 51/159 (32%), Positives = 70/159 (44%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F PLR+E + L ++ +L YVF A+ R+ L GRVPLI
Sbjct: 60 AMGLGLYFAEGEGPKFQRPLRDEAAIRALAPADM--GKLQYVFDAVASIRKALDGRVPLI 117
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P YMVEGGGS
Sbjct: 118 GFSGSP---------------------------------------FTLACYMVEGGGSDD 138
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K LY RP+ H +L T +++ YL Q+ AGAQ
Sbjct: 139 FRHVKAMLYSRPELLHHILEANTQSVIAYLNAQIDAGAQ 177
Score = 42.0 bits (97), Expect = 0.10
Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Frame = +3
Query: 4158 SALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322
+AL I + V+++L +G ++ NLGHG+ DP H GA V+AVH+ SR
Sbjct: 270 NALFAEPAAIEREVERILQSYGQGSGHVFNLGHGISQFADPAHAGALVEAVHRLSR 325
Score = 37.4 bits (85), Expect(3) = 5e-04
Identities = 18/22 (81%), Positives = 19/22 (86%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPL RF LDAAI+FSDIL VP
Sbjct: 37 LQPLDRFPLDAAILFSDILTVP 58
Score = 33.1 bits (74), Expect(2) = 0.11
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +3
Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
I+F K G LE++A G + VGLDWT +AR
Sbjct: 221 IVFTKGGGQWLEDIAAIGADCVGLDWTTDIGQAR 254
Score = 27.7 bits (60), Expect(2) = 0.11
Identities = 13/22 (59%), Positives = 15/22 (68%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYA 3840
+R VG V LQGN DP AL+A
Sbjct: 253 ARARVGAKVALQGNFDPNALFA 274
Score = 27.3 bits (59), Expect(3) = 5e-04
Identities = 14/28 (50%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A F C SP+ E+TLQ
Sbjct: 11 EYRATRARAGSFMGLCTSPDYATEVTLQ 38
Score = 23.1 bits (48), Expect(3) = 5e-04
Identities = 9/9 (100%), Positives = 9/9 (100%)
Frame = +3
Query: 1833 MRQAGRYLP 1859
MRQAGRYLP
Sbjct: 2 MRQAGRYLP 10
gi|15792567|ref|NP_282390.1| uroporphyrinogen decarboxylase [Campylobacter jejuni]
gi|24211637|sp|Q9PN54|DCUP_CAMJE Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|11267841|pir||E81331 uroporphyrinogen decarboxylase (EC 4.1.1.37) Cj1243 [imported] -
Campylobacter jejuni (strain NCTC 11168)
gi|6968676|emb|CAB73497.1| uroporphyrinogen decarboxylase [Campylobacter jejuni subsp. jejuni
NCTC 11168]
Length = 340
Score = 80.9 bits (198), Expect = 2e-13
Identities = 53/162 (32%), Positives = 77/162 (47%)
Frame = +1
Query: 2422 LPLQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGR 2601
+PL+ +GM + G+GP F P+ +DLE+L D + +L YV+ A+ LTR++L+
Sbjct: 75 VPLE-MGMNLRFEKGEGPVFGNPISTLEDLEKL-DDQNAHKKLNYVYDALKLTREKLSQN 132
Query: 2602 VPLIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGG 2781
LIGF G+P W + TYM+EG
Sbjct: 133 KALIGFCGSP---------------WTI------------------------ATYMIEGS 153
Query: 2782 GSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGA 2907
GS A+ K+ LYQ P+ H++L LT L YL Q+ AGA
Sbjct: 154 GSKNYAKCKKMLYQNPELLHKILNKLTQVLKLYLEEQIKAGA 195
Score = 40.4 bits (93), Expect = 0.30
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +3
Query: 1782 FLRAAWGEETDYTPVWCMRQAGRYLP 1859
F+ A + + T YTP+W MRQAGRYLP
Sbjct: 3 FIDACFKKPTPYTPIWMMRQAGRYLP 28
Score = 32.0 bits (71), Expect(2) = 1.1
Identities = 16/22 (72%), Positives = 18/22 (81%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQP+ +DAAIIFSDILVVP
Sbjct: 55 LQPIDILDVDAAIIFSDILVVP 76
Score = 25.4 bits (54), Expect(2) = 1.1
Identities = 13/42 (30%), Positives = 20/42 (47%)
Frame = +1
Query: 1930 LWRASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQ 2055
+W + P Y E R + A DF S C+ + E++LQ
Sbjct: 17 IWMMRQAGRYLPEYMEVR--KQAGDFLSLCKDYKKASEVSLQ 56
gi|37524498|ref|NP_927842.1| uroporphyrinogen decarboxylase [Photorhabdus luminescens subsp.
laumondii TTO1]
gi|36783922|emb|CAE12784.1| uroporphyrinogen decarboxylase [Photorhabdus luminescens subsp.
laumondii TTO1]
Length = 354
Score = 80.9 bits (198), Expect = 2e-13
Identities = 55/161 (34%), Positives = 75/161 (46%), Gaps = 2/161 (1%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLR--DPEVVASELGYVFQAITLTRQRLAGRVP 2607
A+G+ + G+GP F P+ D+E+L DPE+ EL YV A+ R+ LAG+VP
Sbjct: 84 AMGLGLYFEAGEGPRFKSPVFSRADVEKLPVPDPEM---ELSYVTDAVRAIRKALAGQVP 140
Query: 2608 LIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGS 2787
LIGF+G+P W A TYMVEGG S
Sbjct: 141 LIGFSGSP--WTLA-------------------------------------TYMVEGGSS 161
Query: 2788 STMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K+ +Y P H LL L D+++ YL Q+ AGAQ
Sbjct: 162 KAFTKIKKMMYAEPTVMHLLLDKLADSVILYLNAQIKAGAQ 202
Score = 49.7 bits (117), Expect = 5e-04
Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G S L E I Q V +L FG ++ NLGHG++ D+ PEH G FV+AVHK
Sbjct: 288 LQGNMDPSMLYASPERIEQEVSTILQGFGTGSGHVFNLGHGIHQDILPEHAGVFVEAVHK 347
Query: 4314 HSRLLRQ 4334
S Q
Sbjct: 348 LSAKYHQ 354
Score = 47.8 bits (112), Expect(2) = 8e-07
Identities = 21/31 (67%), Positives = 23/31 (74%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND +LRA + D TPVW MRQAGRYLP
Sbjct: 4 LKNDRYLRALLRQSVDVTPVWMMRQAGRYLP 34
Score = 37.4 bits (85), Expect = 2.5
Identities = 20/41 (48%), Positives = 25/41 (60%)
Frame = +2
Query: 2069 KRGKDLCLQSAT*QPVSCFLQPLRRFLLDAAIIFSDILVVP 2191
K G + L T LQPL+R+ LDAAI+FSDIL +P
Sbjct: 42 KAGDFIALCKNTELACEVTLQPLQRYPLDAAILFSDILTIP 82
Score = 34.7 bits (78), Expect(2) = 0.002
Identities = 28/78 (35%), Positives = 33/78 (42%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954
+R VG V LQGN+DP LYAS + +L G VFN L
Sbjct: 278 ARRRVGNKVALQGNMDPSMLYASPERIEQEVSTILQGFGTGSG------HVFN--LGHGI 329
Query: 3955 HLYTISPRKTGLFVAVVH 4008
H I P G+FV VH
Sbjct: 330 H-QDILPEHAGVFVEAVH 346
Score = 32.0 bits (71), Expect(2) = 0.002
Identities = 15/33 (45%), Positives = 20/33 (60%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
+FAK G LE +A+ G + +GLDWT AR
Sbjct: 247 LFAKGGGQWLEAMAETGCDALGLDWTTDIADAR 279
Score = 30.8 bits (68), Expect(2) = 8e-07
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E++ TRA A DF + C++ E CE+TLQ
Sbjct: 35 EYQATRAKAGDFIALCKNTELACEVTLQ 62
gi|28198490|ref|NP_778804.1| uroporphyrinogen decarboxylase [Xylella fastidiosa Temecula1]
gi|32129491|sp|Q87DV0|DCUP_XYLFT Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|28056574|gb|AAO28453.1| uroporphyrinogen decarboxylase [Xylella fastidiosa Temecula1]
Length = 354
Score = 80.9 bits (198), Expect = 2e-13
Identities = 51/159 (32%), Positives = 74/159 (46%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+E+ + G+GP +P+R+ + +L P++ +EL YV A+ L R+ L VPLI
Sbjct: 82 AMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDM-ETELRYVMDAVRLIRKELDNSVPLI 140
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A YM+EGG S
Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGSSKE 161
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
A+ K + P HQLL +TDA++ YL Q AGAQ
Sbjct: 162 YARIKAMAFNAPDVLHQLLNTVTDAVISYLAAQRAAGAQ 200
Score = 45.1 bits (105), Expect = 0.012
Identities = 20/31 (64%), Positives = 22/31 (70%)
Frame = +3
Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
LKND LRA + D TP+W MRQAGRYLP
Sbjct: 2 LKNDRLLRALRRDTVDRTPIWLMRQAGRYLP 32
Score = 40.0 bits (92), Expect = 0.39
Identities = 16/30 (53%), Positives = 23/30 (76%)
Frame = +3
Query: 4233 YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322
++ NLGHG+ P M+P+HV A V+AV + SR
Sbjct: 324 HVFNLGHGMTPGMNPDHVSALVEAVQRLSR 353
Score = 40.0 bits (92), Expect(2) = 0.002
Identities = 18/22 (81%), Positives = 21/22 (95%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRRF LDAAI+FSDIL++P
Sbjct: 59 LQPLRRFPLDAAILFSDILMIP 80
Score = 38.5 bits (88), Expect = 1.1
Identities = 18/52 (34%), Positives = 31/52 (59%)
Frame = +3
Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434
ALQ+F++ G L P ++ F+LPY+ +A++++ R G P+V G G
Sbjct: 201 ALQVFDTWGGILSPTMYRTFSLPYLTRIARELE---RGTGTEHTPLVLFGKG 249
Score = 26.6 bits (57), Expect(2) = 0.002
Identities = 14/45 (31%), Positives = 20/45 (44%)
Frame = +1
Query: 1921 RGGLWRASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQ 2055
R +W + P Y R+ A F ++PE CE+TLQ
Sbjct: 18 RTPIWLMRQAGRYLPEYRAARQH--AGSFLKMAKTPELACEITLQ 60
gi|15640359|ref|NP_229986.1| uroporphyrinogen decarboxylase [Vibrio cholerae O1 biovar eltor str.
N16961]
gi|11267825|pir||C82335 uroporphyrinogen decarboxylase VC0332 [imported] - Vibrio cholerae
(strain N16961 serogroup O1)
gi|9654747|gb|AAF93505.1| uroporphyrinogen decarboxylase [Vibrio cholerae O1 biovar eltor str.
N16961]
Length = 359
Score = 77.4 bits (189), Expect = 2e-12
Identities = 50/159 (31%), Positives = 72/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F P+ + D++++ P+ EL YV A+ R+ L G VPLI
Sbjct: 88 AMGLGLRFAAGEGPVFERPITCKADVDKIGIPDP-EGELQYVMNAVRQIRKDLQGEVPLI 146
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 147 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 167
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K+ +Y P H LL L D+++ YL Q+ AGAQ
Sbjct: 168 FTKIKKMMYSEPTVLHALLDKLADSVISYLNAQIKAGAQ 206
Score = 52.4 bits (124), Expect(3) = 2e-13
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA + DYTPVW MRQAGRYLP
Sbjct: 7 ELKNDRYLRALLKQPVDYTPVWMMRQAGRYLP 38
Score = 44.3 bits (103), Expect = 0.021
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVH 4310
L G S L P I + V +L FG ++ NLGHG++ D+ PE+ G FV+AVH
Sbjct: 292 LQGNMDPSILYAPAPRIREEVASILAGFGQGGTGHVFNLGHGIHLDVPPENAGVFVEAVH 351
Query: 4311 KHSR 4322
+ S+
Sbjct: 352 ELSK 355
Score = 39.7 bits (91), Expect(3) = 2e-13
Identities = 18/22 (81%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRRF LDAAI+FSDIL +P
Sbjct: 65 LQPLRRFPLDAAILFSDILTIP 86
Score = 35.0 bits (79), Expect(2) = 0.002
Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWT--VAPKKAR 3677
+F K+G LE++A G + VGLDWT +A KAR
Sbjct: 251 LFTKNGGMWLEQIAATGCDAVGLDWTINIADAKAR 285
Score = 31.6 bits (70), Expect(2) = 0.002
Identities = 26/74 (35%), Positives = 31/74 (41%)
Frame = +1
Query: 3787 VGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYT 3966
VG V LQGN+DP LYA R + +L VFN L HL
Sbjct: 286 VGDKVALQGNMDPSILYAPAPRIREEVASILAGFGQGG-----TGHVFN--LGHGIHL-D 337
Query: 3967 ISPRKTGLFVAVVH 4008
+ P G+FV VH
Sbjct: 338 VPPENAGVFVEAVH 351
Score = 28.5 bits (62), Expect(3) = 2e-13
Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A DF + C++ E E+TLQ
Sbjct: 39 EYRATRAQAGDFMALCKNAELASEVTLQ 66
gi|23814028|sp|Q9KV26|DCUP_VIBCH Uroporphyrinogen decarboxylase (URO-D) (UPD)
Length = 355
Score = 77.4 bits (189), Expect = 2e-12
Identities = 50/159 (31%), Positives = 72/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F P+ + D++++ P+ EL YV A+ R+ L G VPLI
Sbjct: 84 AMGLGLRFAAGEGPVFERPITCKADVDKIGIPDP-EGELQYVMNAVRQIRKDLQGEVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
+ K+ +Y P H LL L D+++ YL Q+ AGAQ
Sbjct: 164 FTKIKKMMYSEPTVLHALLDKLADSVISYLNAQIKAGAQ 202
Score = 52.4 bits (124), Expect(3) = 2e-13
Identities = 23/32 (71%), Positives = 25/32 (78%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA + DYTPVW MRQAGRYLP
Sbjct: 3 ELKNDRYLRALLKQPVDYTPVWMMRQAGRYLP 34
Score = 44.3 bits (103), Expect = 0.021
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVH 4310
L G S L P I + V +L FG ++ NLGHG++ D+ PE+ G FV+AVH
Sbjct: 288 LQGNMDPSILYAPAPRIREEVASILAGFGQGGTGHVFNLGHGIHLDVPPENAGVFVEAVH 347
Query: 4311 KHSR 4322
+ S+
Sbjct: 348 ELSK 351
Score = 39.7 bits (91), Expect(3) = 2e-13
Identities = 18/22 (81%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRRF LDAAI+FSDIL +P
Sbjct: 61 LQPLRRFPLDAAILFSDILTIP 82
Score = 35.0 bits (79), Expect(2) = 0.002
Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWT--VAPKKAR 3677
+F K+G LE++A G + VGLDWT +A KAR
Sbjct: 247 LFTKNGGMWLEQIAATGCDAVGLDWTINIADAKAR 281
Score = 31.6 bits (70), Expect(2) = 0.002
Identities = 26/74 (35%), Positives = 31/74 (41%)
Frame = +1
Query: 3787 VGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYT 3966
VG V LQGN+DP LYA R + +L VFN L HL
Sbjct: 282 VGDKVALQGNMDPSILYAPAPRIREEVASILAGFGQGG-----TGHVFN--LGHGIHL-D 333
Query: 3967 ISPRKTGLFVAVVH 4008
+ P G+FV VH
Sbjct: 334 VPPENAGVFVEAVH 347
Score = 28.5 bits (62), Expect(3) = 2e-13
Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E+R TRA A DF + C++ E E+TLQ
Sbjct: 35 EYRATRAQAGDFMALCKNAELASEVTLQ 62
gi|15834174|ref|NP_312947.1| uroporphyrinogen decarboxylase [Escherichia coli O157:H7]
gi|23813992|sp|Q8X6X5|DCUP_ECO57 Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|25291010|pir||H91243 uroporphyrinogen decarboxylase [imported] - Escherichia coli (strain
O157:H7, substrain RIMD 0509952)
gi|13364396|dbj|BAB38343.1| uroporphyrinogen decarboxylase [Escherichia coli O157:H7]
Length = 354
Score = 78.2 bits (191), Expect = 1e-12
Identities = 53/159 (33%), Positives = 72/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F P+ + D+++L P+ ELGYV A+ R+ L G VPLI
Sbjct: 84 AMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDP-EDELGYVMNAVRTIRRELKGEVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K+ +Y PQA H LL L ++ YL Q+ AGAQ
Sbjct: 164 FTVIKKMMYADPQALHALLDKLAKSVALYLNAQIKAGAQ 202
Score = 49.3 bits (116), Expect(3) = 2e-13
Identities = 22/32 (68%), Positives = 24/32 (75%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA + D TPVW MRQAGRYLP
Sbjct: 3 ELKNDRYLRALLRQPVDVTPVWMMRQAGRYLP 34
Score = 47.8 bits (112), Expect = 0.002
Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G S L P I + V +L FG ++ NLGHG++ D+ PEH G FV+AVH+
Sbjct: 288 LQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHR 347
Query: 4314 HS 4319
S
Sbjct: 348 LS 349
Score = 38.9 bits (89), Expect(3) = 2e-13
Identities = 18/22 (81%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRR+ LDAAI+FSDIL VP
Sbjct: 61 LQPLRRYPLDAAILFSDILTVP 82
Score = 32.3 bits (72), Expect(3) = 2e-13
Identities = 15/28 (53%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E++ TRA A DF S C++ E CE+TLQ
Sbjct: 35 EYKATRAQAGDFMSLCKNAELACEVTLQ 62
Score = 32.0 bits (71), Expect(2) = 0.041
Identities = 26/78 (33%), Positives = 32/78 (41%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954
+R VG V LQGN+DP LYA + +L G VFN L
Sbjct: 278 ARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEG------HVFN--LGHGI 329
Query: 3955 HLYTISPRKTGLFVAVVH 4008
H + P G+FV VH
Sbjct: 330 H-QDVPPEHAGVFVEAVH 346
Score = 30.4 bits (67), Expect(2) = 0.041
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
+F K G LE +A+ G + +GLDWT AR
Sbjct: 247 LFTKGGGQWLEAMAETGCDALGLDWTTDIADAR 279
gi|16131827|ref|NP_418425.1| uroporphyrinogen decarboxylase [Escherichia coli K12]
gi|1352226|sp|P29680|DCUP_ECOLI Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|7436556|pir||H65206 uroporphyrinogen decarboxylase (EC 4.1.1.37) - Escherichia coli
(strain K-12)
gi|2367337|gb|AAC76971.1| uroporphyrinogen decarboxylase [Escherichia coli K12]
Length = 354
Score = 78.2 bits (191), Expect = 1e-12
Identities = 53/159 (33%), Positives = 72/159 (45%)
Frame = +1
Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613
A+G+ + G+GP F P+ + D+++L P+ ELGYV A+ R+ L G VPLI
Sbjct: 84 AMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDP-EDELGYVMNAVRTIRRELKGEVPLI 142
Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793
GF+G+P W A TYMVEGG S
Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163
Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910
K+ +Y PQA H LL L ++ YL Q+ AGAQ
Sbjct: 164 FTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQ 202
Score = 49.3 bits (116), Expect(3) = 2e-13
Identities = 22/32 (68%), Positives = 24/32 (75%)
Frame = +3
Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859
ELKND +LRA + D TPVW MRQAGRYLP
Sbjct: 3 ELKNDRYLRALLRQPVDVTPVWMMRQAGRYLP 34
Score = 47.8 bits (112), Expect = 0.002
Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +3
Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313
L G S L P I + V +L FG ++ NLGHG++ D+ PEH G FV+AVH+
Sbjct: 288 LQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHR 347
Query: 4314 HS 4319
S
Sbjct: 348 LS 349
Score = 38.9 bits (89), Expect(3) = 2e-13
Identities = 18/22 (81%), Positives = 20/22 (90%)
Frame = +2
Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191
LQPLRR+ LDAAI+FSDIL VP
Sbjct: 61 LQPLRRYPLDAAILFSDILTVP 82
Score = 32.3 bits (72), Expect(3) = 2e-13
Identities = 15/28 (53%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Frame = +1
Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055
E++ TRA A DF S C++ E CE+TLQ
Sbjct: 35 EYKATRAQAGDFMSLCKNAELACEVTLQ 62
Score = 32.0 bits (71), Expect(2) = 0.041
Identities = 26/78 (33%), Positives = 32/78 (41%)
Frame = +1
Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954
+R VG V LQGN+DP LYA + +L G VFN L
Sbjct: 278 ARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEG------HVFN--LGHGI 329
Query: 3955 HLYTISPRKTGLFVAVVH 4008
H + P G+FV VH
Sbjct: 330 H-QDVPPEHAGVFVEAVH 346
Score = 30.4 bits (67), Expect(2) = 0.041
Identities = 14/33 (42%), Positives = 19/33 (57%)
Frame = +3
Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677
+F K G LE +A+ G + +GLDWT AR
Sbjct: 247 LFTKGGGQWLEAMAETGCDALGLDWTTDIADAR 279
Uroporphyrinogen decarboxylase (URO-D) (UPD)
gi|3660278|pdb|1URO|A 
Chain A, Uroporphyrinogen Decarboxylase
gi|2905794|gb|AAC03563.1|