TTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFSMASTPDEKGFI
ELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDEERPMILIAGGTGFSYARSI
LLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHPGLQVVPVVEQPEAGWRGRTGT
VLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
1. Has this protein sequence simmilarity to other with a known
structure?.
The results from a "BLAST
against PDB" search indicate that there isn't a known structure with
sequence simmilarity to our query.
2.- Structure related information in the databases:
SwissProt
File
In this case, swissprot contain information about the active site of
the protein (pyridine binding).
3.- Results from Threading programs:
TOPITS
results (+PHD: secondary structure)
Threader2
results
4.- Predicted folding comparation:
Some of the predicted folds are structuraly related:
FSSP
comparison results file
5.- Threading on 2cnd structure and mapping of the
known data
Based on the secondary structure data, the protein could have two domains,
one "all beta" and another one "mixed alpha-beta". The active site (pyridine
binding) of the query protein is located in the same spatial place as the
template (2cnd) structure.
6.- And, finally, a comparison between the
threading predicted structure and the actual one:
RED: The threading predicted model.
GREEN: The actual structure.
And, [HERE], the PDB file of the above comparison structure.