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    MOST USED
    • PubMed
    • Google
    • SRS-EBI
    • translator-ya.com (..)
    • english->spanish
    • spanish->english
    • Paulino-directlinks
    Federico Abascal

    Protein Design Group - CNB - UAM
    fabascal@cnb.uam.es

    Want to do recursive sequence searches and cluster the results to detect false positives, to asses remote homology relationships, to analyze the evolutionary history of a protein family, ...? Try the recursive-blast and Ncut-clustering server.

    What's genetic engineering for (an introduction)?
     
    Sequence Alignments
    Blast EMBL, NCBI (2 seqs), EBI
    PSI-Blast NCBI
    Bioccelerator (S&W)
    Sam - HMM
    Align 2 sequences S&W
    Clustal EBI
    AQUA(Alignment QUality Assessment)

    Sequence features
    TMHMM, TMpred, all
    COILS, Paircoil, Multicoil
    SignalP, Sigcleave.pm,
    ExPASy - Tools, PattinProt

    Protein Families
    PROTOMAP (old)
    SYSTERS
    PFAM
    COGs: orthologues&paralogues
    CluS+Tr
     

    GeneFinding
    MetaGene
    GeneMark
    ORF Finder
    PROCRUSTES
    geneid
    tRNAscan-SE

    Genomes
    Genomes at NCBI: bacteria, human (NHGRI), Drosophila melanogaster.
    Genome Protemics (EBI)
    CUBIC: genome analysis and descr.    s 
        s 
    Other
    GeneQuiz
    Coils
    RDB

    Programming
    Many tutorials(from www.cs.huji.ac.il)
    Perl
    Perl Quick Reference
    Perl Reference
    search.cpan.org
    Java
    Java tutorial from Sun
    Java Reference (1.1.6) index
    Other
    HTML, more
    PostgreSQL
    Latex, more
    XML intro (en español)
    netlib - math algorithms
    Meschach tut, and others

    Browsers / links
    SRS-EMBL CNB library (search) Infoseek
    SRS-EBI PubMed & Cubby FAST FTP Search v4.0
    SRS-INFOBIOGEN SeqAnalRef Yahoo
    SRS-CNB UAM library Google
    Pise-CNB BioMedNet BioHunt
    Pedro's BioMolecular Research Tools Infotrieve - Free Medline
    PDBsum EBI's BioCatalog CalPhotos
    OCA EBI's Software rep.

 
     
    Bio Centers
    EMBnet
    EBI
    Sanger
    NCBI
    EMBL
    MIPS
    Weizmann
    WUSTL
    UCSC

    Journals
    Bioinformatics
    Current Opinions
    JMB
    Nature
    PNAS
    NAR
    Protein Engineering
    Science
    List of BioJournals
    ISMB 99
    Graph algorithms
    Databases
    SCOP
    FSSP
    HSSP
    CATH
    PDB (lite)

    KEGG (docs)

    TRANSFAC
    SWISSPROT&SPTREMBL
    OWL

    DBCat
    NCBI-dBases
    LINKS!!
    NAR DBases Issue 99,  00,01

    PRODOM
    Prosite
    Blocks
    PFAM
    PROTOMAP

     
    Genomes
    Under construction
    Human genome:
    • what (and where from) can we get about human genome (nature)
    • Initial sequencing and analysis of the human genome by the Public Consortium (nature)
    • annotation at UCSC
    • Human Project Information.
    • The National Human Genome Research Institute (NHGRI)

    • the human genome atNCBI.
    BioTutorials
    • Course on Computational Molecular Biology at WUSTL
    • Introduction to Alignment Scoring Statistics (WUSTL)
    • General course on Bioinformatics (UAM, Paulino Gómez Puertas)
    • Pedestrian guide to analysing sequence databases (B.Rost and R.Schneider)
    • Swiss-PdbViewer manual (expasy); another one (simpler) by Gale Rhodes
    • Crystallography Made Crystal Clear (CMCC): Crystallography, NMR, Homology Modeling, Electron density maps, ....
    • Rasmol tutorial by Gale Rhodes
    • Rasmol manual by Roger Sayle
    • Information about protein families (ProWeb Project)
    • Tutorials from KEGG: pathways maps, genome maps, global function, ...
    • ergito/genes.net's GENES online, famous experiments, cell biology, molecular biology
    • Principles of Protein Structure, Comparative Protein Modelling and Visualisation at ExPASy (N.Guex and M.C. Peitsch)
    • FSSP - help
    • Protein structure prediction (an introduction, by Harry Mangalam).
    • NCBI education
    • BioComputing Hypertext Coursebook about alignments, substitution matrices, algorithms, phylogenetics, etc
    • Multiple tutorials on Unix, GCG, Seqlab & Staden Tutorials from the University of Oxford
    • Introto Statistics of similarity scores (NCBI)
    • Course Statistics for the life sciences (Department of Statistics and Mathematics, Simon Fraser University)
    • Courses of the EMBL sequence analysis service
    • Glossary of genetic terms.
    • David Gilbert courses. Introduction to bioinformatics (protein topology).
    • Tutorial on Protein Alignments (sequence and structural ones; Mark Gerstein, Yale MB&B)
    • Algorithms in Molecular Biology (Ron Shamir , Tel Aviv University Department of Computer Science)
    • Graph algorithms good course about NP optimization problems.
    • GCG manual (CNB); Wisconsin
    • Links to a lot of courses and tutorials (CCP11 project - The Bioinformatics resource).
    • More links (from Infobiogen).
    • And more...  (from Ron Shamir , Tel Aviv University)
    • Gene Finding Review by David Haussler
    • EMBnet/CNB Computing Library
    • Principal component analysis
    • Pfam statistics (Bayesian model, bit scores, extreme value distr., etc)
    • HMMER package documentation (from Dr. Sean Eddy, WUSTL; local copy)
    • Graph algorithms applet (very pretty!!), RIOT, Dorit S.Hochbaum and Dr Olivier Goldschmidt.
    Mathematics
    The Stony Brook Algorithm Repository
    StadHelp  (help with biostatistics, in spanish)
    Bioestadística (uma)
    netlib - math algorithms
    Principal component analysis
    Course Statistics for the life sciences (Simon Fraser University)
    Search for mathematics topics
    Mathematical Atlas: A gateway to Mathematics
    Eric Weisstein's World of Mathematics
    Mathematica
    Elementary Linear Algebra (Keith Matthews)
    Linear Algebra (Jim Hefferon)
    linear + algebra google's search

     
    Language - Encyclopedias -
    Dictionaries - Online books

    Español
    La Página del Idioma Español
    Diccionario de la RAE
    Diccionarios, sinónimos, dudas, etc;
    Acentos-reglas
    Diccionario de burradas
    Diccionarios Anaya
    LINKS!!

    Encyclopedia
    Enciclopedias (from EL PAIS)
    Encyclopedia Britannica

    Translators
    e-lingo, babelfish, go translator, traductor-ya

    Newspapers
    EL PAIS
    La Vanguardia
    El Mundo
    MiCanoa.com
    larazon
    Estrella Digital
     

    Internet tools
    MailAndNews
    Sauce
    hotmail
    freenewsland.com
    Mixmail
    Bigfoot


    Biology
    GENES online
    Cell and molecular biology dictionary
    Virtual Biology
    Kimball's Biology Pages
    Special Interest Groups at NIH
    Virtual Library: Biosciences, Computer science, etc
    Cell and Mol. Biol online
    A Level Biology
    Human Phisiology
    The Biology Project
    A Molecular Biology Notebook
    MIT's Biology Hypertextbook
    Glossary of genetic terms
    Glossary of Biochemistry and Molecular Biology.

     
    Science Divulgation
    Under construction
    www.sciencedaily.com
    www.explorezone.com
    www.100cia.com
    www.divulcat.com
    www.astrored.com
    www.bioplanet.net

     
    People
    Shamir , Tel Aviv University
    José María, PDG-CNB
    Ghale Rhodes (Macromolecular models, tutorials, links, etc), University of Southern Maine
    Luis, PDG-CNB
    Burkhardt Rost, CUBIC
    Roderic Guigó, IMIM i UB
    Golan Yona, Stanford University
    Jong Park, Medical Research Council
    Samuel Karlin, Stanford University
    Sean Eddy, WUSTL
    David Gilbert (links), City University
     

    Impossible to classify (for me) links:
    man & info pages (local access)
    ESTUDIOS DE DOCTORADO-TERCER CICLO

    Other links
    Protein Structure Initiative (PSI)
    Bioperl.org
    Bioinformatics.org
    Sean Eddy's Lab Publications (WUSTL)

    Links pages
    THE BIOLIST- Molecular Biology Places of Interest
    BioChemLinks (biochemistry)
    Databases
    Bioinformatics Tutorials: 1, 2, 3
    EBI's Software rep.
    EMBnet Molecular Biology tools, development tools.
    Gene Identification tools (list of sites)
    The Computational Biology group at USC Software tools
    Bioinformatics Resources (NBIF)
    List of BioJournals
    Damien's links, Luis' links, Paulino's links
    Pedro's BioMolecular Research Tools
    David Gilbert's links
    EBI's BioCatalog
    Interpreting biol. seqs. links

    Madrid
    Some interesting places:
    i.-  Museo del Prado
    ii.- Tyssen-Bornemisza Museum
    iii.- Plaza Mayor(more)
    iv.-Palacio Real
    v.- Jardín Botánico
    vi.-Parque del Retiro
    vii- Museo Reina Sofía
    Useful links to live Madrid:
    Madrid's map
    MuniMadrid
    METRO
    Guía del Ocio
    Madrid a mano
    5 days in Madrid guide
    Madrid cinema's program (vamos, la cartelera)
    Cartelera y TV de EL PAIS
    Cinentradas (venta electrónica)
    Comunidad de Madrid
    AboutMadrid

     
    Personal
    I'm working at the CNB Protein Design Group (see some people of the group feeding them selves, here) since January 1999, doing my thesis with a fellowship from Comunidad de Madrid since October 1999 (thanks!). I'm working in automatic function prediction in the context of genomic biology in collaboration with José María Fernández.You can find us here.
    Go here if you want to know more about my interests at Bioinformatics and/or Computational Biology.
    If you want to comment something with me, please do it (email).

     

    Publications

    • Here you can find the poster I presented at the "Structural Genomics and Bioinformatics" workshop in the Juan March Institute (March 2001).
    • An article published at CNN+ online can be found here. (or a local version here, in spanish)
    • And here, the poster that José María and me presented at "II Jornadas de Bioinformática", (Malaga, May 2001)
    • Clustering of proximal sequence space for the identification of protein families.
      • Federico Abascal and Alfonso Valencia
        Bioinformatics 2002;18:908-921.
        (suplementary material)
    • Reductive genome evolution in Buchnera aphidicola.
      • Van Ham RC, Kamerbeek J, Palacios C, Rausell C, Abascal F, Bastolla U, Fernandez JM, Jimenez L, Postigo M, Silva  J, Tamames J, Viguera E, Latorre A, Valencia A, Moran F, Moya A.
        Proc Natl Acad Sci U S A. 2003;100:581-586
        (project web-site)
    • Automatic annotation of protein function based on family identification.
      • Federico Abascal and Alfonso Valencia.
        Proteins. 2003; 50:683-692.
        (suplementary material)
    • Mi tesis: Análisis de genomas. Métodos para la predicción y anotación de la función de las proteínas. (septiembre 2003)
      • PDF: portada y agradecimientos, contenido.
        PS: portada y agradecimientos, contenido.

       
       
    Clases - Teaching
    • UCM - Escuela de verano 2003: Análisis de Secuencias.
      • Alineamiento de secuencias. Búsqueda de parecidos. Alineamientos múltiples.
      • Motivos y perfiles. Dominios. Familias de Proteínas.
    • Máster de Bioinformática 2003: Análisis de secuencias. Patrones, perfiles, dominios y familias de proteínas.
      • Patrones, perfiles y dominios.
      • Más sobre patrones y perfiles: PSI-BLAST y HMMer.
      • Familias de proteínas.
    • UAM - curso de doctorado 2003: Análisis de secuencias: Búsqueda de homólogos con BLAST y PSI-BLAST.
    • UAM - curso de doctorado 2002: El papel de las familias de proteínas en el análisis de secuencias.
    • UCM - Escuela de verano 2002: Familias de Proteínas.

     
     

    Contact information:
    Federico Abascal
    Protein Design Group, CNB-CSIC
    Cantoblanco Madrid 28049 Spain
    phone +34 91 585 46 69  fax: +34 91 585 45 06
    email: fabascal@cnb.uam.es http://www.pdg.cnb.uam.es/fabascal
    UAM map

     
     
     
  • Wolves photos by Gerald and Buff Corsi. Copyright © 2001 California Academy of Sciences.
  • Moon photos from NASA website.
  • Other photos: National Geographic, Corbis, ??etc??(sorry)

  •  

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    BioBooks - Bio Centers - Bio Tutorials- Browsers - Databases - Dictionaries - Español - Genomes - Interests - Journals - Links-pages - Madrid   - mail/news - Mathematics - Newspapers - People - Personal - Publications