Supporting Table 1. Comparative annotation of Buchnera genomes. LCSA, last common symbiont ancestor of Buchnera strains. BBp, Buchnera aphidicola, endosymbiont of Baizongia pistaciae. BAp, Buchnera aphidicola, endosymbiont of Acyrthosiphon pisum. Bsg, Buchnera aphidicola, endosymbiont of Schizaphis graminum. In green, missing genes in some of the three symbionts; in red, pseudogenes.

 

Position

LCSA

BBp

BAp

BSg

Function 

1

gidA

+

+

+

DNA replication, recombination, modification and repair 

2

atpB

+

+

+

Energy metabolism 

3

atpE

+

+

+

Energy metabolism 

4

atpF

+

+

+

Energy metabolism 

5

atpH

+

+

+

Energy metabolism 

6

atpA

+

+

+

Energy metabolism 

7

atpG

+

+

+

Energy metabolism 

8

atpD

+

+

+

Energy metabolism 

9

atpC

+

+

+

Energy metabolism 

10

gyrB

+

+

+

DNA replication, recombination, modification and repair 

11

dnaN

+

+

+

DNA replication, recombination, modification and repair 

12

dnaA

+

+

+

DNA replication, recombination, modification and repair 

13

rpmH

+

+

+

Translation, post-translational modification 

14

rnpA

+

+

+

DNA replication, recombination, modification and repair 

15

yidD

+

-

+

Hypothetical, unclassified, unknown 

16

yidC

+

+

+

Hypothetical, unclassified, unknown 

17

thdF

+

+

+

Cell processes (incl. adaptation, protection) 

18

mutH

+

-

-

DNA replication, recombination, modification and repair 

19

tRNA-Phe

+

+

+

RNAs 

20

mopB

+

+

+

Cell processes (incl. adaptation, protection) 

21

mopA

+

+

+

Cell processes (incl. adaptation, protection) 

22

yjeK

+

-

+

Amino acid biosynthesis and metabolism 

23

efp

+

+

+

Translation, post-translational modification 

24

dnaC

+

+

+

DNA replication, recombination, modification and repair 

25

dnaT

-

+

+

DNA replication, recombination, modification and repair 

26

yhhF

+

+

+-

Hypothetical, unclassified, unknown 

27

ftsY

+

+

+

Cell processes (incl. adaptation, protection) 

28

rpoH

+

+

+

Transcription, RNA processing and degradation 

29

glmS

+

+

+

Central intermediary metabolism 

30

glmU

+

+

+

Central intermediary metabolism 

31

yigL

+

+-

+

Hypothetical, unclassified, unknown 

32

metR

-

+-

+

Amino acid biosynthesis and metabolism 

33

metE

+

+

+

Amino acid biosynthesis and metabolism 

34

purH

+

+

+

Nucleotide biosynthesis and metabolism 

35

hupA

+

+

+

DNA replication, recombination, modification and repair 

36

rpoC

+

+

+

Transcription, RNA processing and degradation 

37

rpoB

+

+

+

Transcription, RNA processing and degradation 

38

rplL

+

+

+

Translation, post-translational modification 

39

rplJ

+

+

+

Translation, post-translational modification 

40

rplA

+

+

+

Translation, post-translational modification 

41

rplK

+

+

+

Translation, post-translational modification 

42

nusG

+

+

+

Transcription, RNA processing and degradation 

43

secE

+

+

+

Transport and binding proteins 

44

tRNA-Thr

+

+

+

RNAs 

45

tRNA-Gly

+

+

+

RNAs 

46

tRNA-Tyr

+

+

+

RNAs 

47

tRNA-Thr

+

+

+

RNAs 

48

murB

+

+

+

Cell structure 

49

metF

+

+

+

Central intermediary metabolism 

50

argE

-

+

+

Amino acid biosynthesis and metabolism 

51

argC

-

+

+

Amino acid biosynthesis and metabolism 

52

argB

-

+

+

Amino acid biosynthesis and metabolism 

53

argG

+

+

+

Amino acid biosynthesis and metabolism 

54

argH

+

+

+

Amino acid biosynthesis and metabolism 

55

yibN

+

+

+

Hypothetical, unclassified, unknown 

56

secB

-

+

+

Transport and binding proteins 

57

cysE

+

+

+

Amino acid biosynthesis and metabolism 

58

rpoD

+

+

+

Transcription, RNA processing and degradation 

59

dnaG

+

+

+

DNA replication, recombination, modification and repair 

60

rpsU

+

+

+

Translation, post-translational modification 

61

ygjD

+

+

+

Energy metabolism 

62

ribB

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

63

yb3052

-

+

+

Central intermediary metabolism 

64

cca

+

+

+

Translation, post-translational modification 

65

bacA

+

+

+

Cell processes (incl. adaptation, protection) 

66

crr

+

+

+

Transport and binding proteins 

67

ptsI

+

+

+

Transport and binding proteins 

68

ptsH

+

+

+

Transport and binding proteins 

69

cysK

-

+

+

Amino acid biosynthesis and metabolism 

70

lig

+

+

+-

DNA replication, recombination, modification and repair 

71

tRNA-Lys

+

+

+

RNAs 

72

tRNA-Val

+

+

+

RNAs 

73

gltX

+

+

+

Translation, post-translational modification 

74

tRNA-Ala

+

+

+

RNAs 

75

fliE

+

+

+

Cell structure 

76

fliF

+

+

+

Cell structure 

77

fliG

+

+

+

Cell structure 

78

fliH

+

+

+

Cell structure 

79

fliI

+

+

+

Cell processes (incl. adaptation, protection) 

80

fliJ

+

+

+

Cell processes (incl. adaptation, protection) 

81

fliK

+

+

+

Cell processes (incl. adaptation, protection) 

82

fliM

+

+

+

Cell structure 

83

fliN

+

+

+

Cell structure 

84

fliOP

+

+

+

Cell structure 

85

fliQ

+

+

+

Cell structure 

86

fliR

+

+

+

Cell structure 

87

rpmG

+

+

+

Translation, post-translational modification 

88

rpmB

+

+

+

Translation, post-translational modification 

89

ytfN

+

+

+

Hypothetical, unclassified, unknown 

90

ppa

+

+

+

Central intermediary metabolism 

91

pmbA

+

+

+

Translation, post-translational modification 

92

rnpB

+

+

+

RNAs 

93

yraL

+

+

+

Hypothetical, unclassified, unknown 

94

fabB

+

+

+

Fatty acid and phospholipid metabolism 

95

talA

+

+

+

Energy metabolism 

96

tktB

+

+

+

Energy metabolism 

97

dapE

+

+

+

Amino acid biosynthesis and metabolism 

98

dapA

+

+

+

Amino acid biosynthesis and metabolism 

99

bcp

-

-

+

Transport and binding proteins 

100

aroC

+

+

+

Amino acid biosynthesis and metabolism 

101

yb2331

+

+

+

Hypothetical, unclassified, unknown 

102

hisG

+

+

+

Amino acid biosynthesis and metabolism 

103

hisD

+

+

+

Amino acid biosynthesis and metabolism 

104

hisC

+

+

+

Amino acid biosynthesis and metabolism 

105

hisB

+

+

+

Amino acid biosynthesis and metabolism 

106

hisH

+

+

+

Amino acid biosynthesis and metabolism 

107

hisA

+

+

+

Amino acid biosynthesis and metabolism 

108

hisF

+

+

+

Amino acid biosynthesis and metabolism 

109

hisI

+

+

+

Amino acid biosynthesis and metabolism 

110

gnd

+

+

+

Energy metabolism 

111

dcd

+

+

+

Nucleotide biosynthesis and metabolism 

112

metG

+

+

+

Translation, post-translational modification 

113

mesJ

+

+

+

Cell processes (incl. adaptation, protection) 

114

tRNA-Val

+

+

+

RNAs 

115

norM

+

-

-

Hypothetical, unclassified, unknown 

116

ribE

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

117

rnfA

+

+

+

Other known genes 

118

rnfB

+

+

+

Other known genes 

119

rnfC

+

+

+-

Other known genes 

120

ydgO

+

+

+

Other known genes 

121

rnfG

+

+

+

Other known genes 

122

ydgQ

+

+

+

Hypothetical, unclassified, unknown 

123

nth

+

+

+

Transcription, RNA processing and degradation 

124

priA

-

+

+

DNA replication, recombination, modification and repair 

125

tyrS

+

+

+

Translation, post-translational modification 

126

ydiC

+

+

+

Hypothetical, unclassified, unknown 

127

yb1688

+

+

+

Hypothetical, unclassified, unknown 

128

aroH

+

+

+

Amino acid biosynthesis and metabolism 

129

thrS

+

+

+

Translation, post-translational modification 

130

infC

+

+-

+-

Translation, post-translational modification 

131

rpmI

+

+

+

Translation, post-translational modification 

132

rplT

+

+

+

Translation, post-translational modification 

133

pheS

+

+

+

Translation, post-translational modification 

134

pheT

+

+

+

Translation, post-translational modification 

135

himA

-

+

+

DNA replication, recombination, modification and repair 

136

queA

-

+

+

Translation, post-translational modification 

137

tgt

-

+

+

Translation, post-translational modification 

138

yajC

+

+

+

Hypothetical, unclassified, unknown 

139

glyS

+

+

+

Translation, post-translational modification 

140

glyQ

+

+

+

Translation, post-translational modification 

141

folE

-

+-

+

Biosynthesis of cofactors, prosthetic groups and carriers

142

nfo

+

+

+

Transcription, RNA processing and degradation 

143

rplY

+

+

+

Translation, post-translational modification 

144

yabI

+

+

+

Hypothetical, unclassified, unknown 

145

surA

-

+

+

Other known genes 

146

ksgA

+

+

+

Cell processes (incl. adaptation, protection) 

147

apaH

+

+

+

Nucleotide biosynthesis and metabolism 

148

folA

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

149

carB

+

+

+

Nucleotide biosynthesis and metabolism 

150

carA

+

+

+

Nucleotide biosynthesis and metabolism 

151

dapB

+

+

+

Amino acid biosynthesis and metabolism 

152

lytB

+

+

+

Regulatory function 

153

lspA

+

+

+

Transport and binding proteins 

154

ileS

+

+

+

Translation, post-translational modification 

155

ribF

-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

156

rpsT

+

+

+

Translation, post-translational modification 

157

dnaJ

+

+

+

Cell processes (incl. adaptation, protection) 

158

dnaK

+

+

+

Cell processes (incl. adaptation, protection) 

159

nuoA

+

+

+

Energy metabolism 

160

nuoB

+

+

+

Energy metabolism 

161

nuoCD

+

+

+

Energy metabolism 

162

nuoE

+

+

+

Energy metabolism 

163

nuoF

+

+

+

Energy metabolism 

164

nuoG

+

+

+

Energy metabolism 

165

nuoH

+

+

+

Energy metabolism 

166

nuoI

+

+

+

Energy metabolism 

167

nuoJ

+

+

+

Energy metabolism 

168

nuoK

+

+

+

Energy metabolism 

169

nuoL

+

+

+

Energy metabolism 

170

nuoM

+

+

+

Energy metabolism 

171

nuoN

+

+

+

Energy metabolism 

172

ygjT

+

-

+

Transport and binding proteins 

173

folC

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

174

cvpA

+

+-

+-

Cell processes (incl. adaptation, protection) 

175

prsA

+

+

+

Nucleotide biosynthesis and metabolism 

176

ychB--pseudogene

+-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

177

prfA

+

+

+

Translation, post-translational modification 

178

hemK

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

179

ychA

+

+

+

Hypothetical, unclassified, unknown 

180

nadE

-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

181

ackA

+

+

+

Energy metabolism 

182

pta

+

+

+

Energy metabolism 

183

yfaE

+

+

+-

Hypothetical, unclassified, unknown 

184

nrdB

+

+

+

Nucleotide biosynthesis and metabolism 

185

nrdA

+

+

+

Nucleotide biosynthesis and metabolism 

186

gyrA

+

+

+

DNA replication, recombination, modification and repair 

187

yba2

+

+

+

Hypothetical, unclassified, unknown 

188

ahpC

+

+

+

Cell processes (incl. adaptation, protection) 

189

ung

+

+

+-

DNA replication, recombination, modification and repair 

190

grpE

+

+

+

Cell processes (incl. adaptation, protection) 

191

yfjB

+

+

+

Hypothetical, unclassified, unknown 

192

tmRNA

+

+

+

RNAs 

193

smpA

-

+

+

Cell structure 

194

ydhD

+

+

+

Hypothetical, unclassified, unknown 

195

rnt

+

+

+

DNA replication, recombination, modification and repair 

196

sodA

+

+

+

Cell processes (incl. adaptation, protection) 

197

pth

+

+

+

Translation, post-translational modification 

198

ychF

+

+

+

Hypothetical, unclassified, unknown 

199

thrC

+

+

+

Amino acid biosynthesis and metabolism 

200

thrB

+

+

+

Amino acid biosynthesis and metabolism 

201

thrA

+

+

+

Amino acid biosynthesis and metabolism 

202

hpt

-

+

+

Nucleotide biosynthesis and metabolism 

203

panC

-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

204

panB

-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

205

dksA

+

+

+

DNA replication, recombination, modification and repair 

206

truA

+

+

+

Translation, post-translational modification 

207

mrcB

+

+

+-

Cell structure 

208

secA

+

+

+

Transport and binding proteins 

209

mutT

-

+

+

Nucleotide biosynthesis and metabolism 

210

yacE

-

+

+

Hypothetical, unclassified, unknown 

211

guaC

+

+

+

Nucleotide biosynthesis and metabolism 

212

aceE

+

+

+

Energy metabolism 

213

aceF

+

+

+

Energy metabolism 

214

lpdA

+

+

+

Energy metabolism 

215

speD

-

+

+

Central intermediary metabolism 

216

speE

-

+

+

Central intermediary metabolism 

217

pfs

+

+

+

Hypothetical, unclassified, unknown 

218

yadR

+

+

+

Hypothetical, unclassified, unknown 

219

ftsZ

+

+

+

Cell processes (incl. adaptation, protection) 

220

ftsA

+

+

+

Cell processes (incl. adaptation, protection) 

221

ddlB

+

+-

+

Cell structure 

222

murC

+

+

+-

Cell structure 

223

murG

+

+

+

Cell structure 

224

ftsW

+

+

+

Cell processes (incl. adaptation, protection) 

225

murD

+

+

+

Cell structure 

226

mraY

+

+

+-

Cell structure 

227

murF

+

+

+-

Cell structure 

228

murE

+

+

+-

Cell structure 

229

ftsI

+

+

+

Cell processes (incl. adaptation, protection) 

230

ftsL

+

+

+

Cell processes (incl. adaptation, protection) 

231

yabC

+

+

+

Hypothetical, unclassified, unknown 

232

ilvH

+

+

+

Amino acid biosynthesis and metabolism 

233

ilvI

+

+

+

Amino acid biosynthesis and metabolism 

234

apbE

+

+-

+-

Biosynthesis of cofactors, prosthetic groups and carriers

235

htrA

+

+

+

Translation, post-translational modification 

236

dapD

+

+

+

Amino acid biosynthesis and metabolism 

237

map

+

+

+

Translation, post-translational modification 

238

rpsB

+

+

+

Translation, post-translational modification 

239

tsf

+

+

+

Translation, post-translational modification 

240

pyrH

+

+

+

Nucleotide biosynthesis and metabolism 

241

frr

+

+

+

Translation, post-translational modification 

242

dxr--pseudogene

+-

+

+

Hypothetical, unclassified, unknown 

243

uppS

+

+

+

Central intermediary metabolism 

244

yaeT

-

+

+

Cell structure 

245

fabZ

+

-

+

Fatty acid and phospholipid metabolism 

246

dnaE

+

+

+

DNA replication, recombination, modification and repair 

247

proS

+

+

+

Translation, post-translational modification 

248

flhB

+

+

+

Cell processes (incl. adaptation, protection) 

249

flhA

+

+

+

Cell structure 

250

argS

+

+

+

Translation, post-translational modification 

251

rrf-16S rRNA

+

+

+

RNAs 

252

tRNA-Ile

+

+

+

RNAs 

253

tRNA-Ala

+

+

+

RNAs 

254

gloB

+

+

+

Hypothetical, unclassified, unknown 

255

rnhA

+

+-

+

DNA replication, recombination, modification and repair 

256

dnaQ

+

+

+

DNA replication, recombination, modification and repair 

257

tRNA-Asp

+

+

+

RNAs 

258

lpcA

-

+

+

Cell structure 

259

gpt

+

+

+

Nucleotide biosynthesis and metabolism 

260

grpE1

+

+

+

Cell processes (incl. adaptation, protection) 

261

yfjF

+

+

+

Hypothetical, unclassified, unknown 

262

smpB

+

+

+

Hypothetical, unclassified, unknown 

263

yfhC

+

+

+

Other known genes 

264

acpS

+

+

+

Fatty acid and phospholipid metabolism 

265

era

+

+

+

Regulatory function 

266

rnc

+

+

+

DNA replication, recombination, modification and repair 

267

lepB

+

+

+

Transport and binding proteins 

268

lepA

+

+

+

Translation, post-translational modification 

269

trmU

+

+

+

Translation, post-translational modification 

270

ycfC

+

+

-

Hypothetical, unclassified, unknown 

271

purB

+

+

+

Nucleotide biosynthesis and metabolism 

272

mltE

+

+

+-

Energy metabolism 

273

fabI

+

+

+

Fatty acid and phospholipid metabolism 

274

rnb

+

+

+

DNA replication, recombination, modification and repair 

275

ychE

+

+

+

Transport and binding proteins 

276

lipB

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

277

lipA

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

278

pyrF

+

+

+

Nucleotide biosynthesis and metabolism 

279

ribA

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

280

hns

-

+

-

DNA replication, recombination, modification and repair 

281

cls

+

+

+

Fatty acid and phospholipid metabolism 

282

yciA

+

+

+

Hypothetical, unclassified, unknown 

283

yciB

+

+

+

Cell processes (incl. adaptation, protection) 

284

yciC

+

+

+

Hypothetical, unclassified, unknown 

285

trpA

+

+

+

Amino acid biosynthesis and metabolism 

286

trpB

+

+

+

Amino acid biosynthesis and metabolism 

287

trpC

+

+

+

Amino acid biosynthesis and metabolism 

288

trpD

+

+

+

Amino acid biosynthesis and metabolism 

289

yedA--pseudogene

+-

+

+

Energy metabolism 

290

yciL

+

+

+

Hypothetical, unclassified, unknown 

291

sohB

+

+

+

Cell processes (incl. adaptation, protection) 

292

topA

-

+

+

DNA replication, recombination, modification and repair 

293

suhB

+

+

+

Regulatory function 

294

yfgB

+

+

+

Other known genes 

295

gcpE--pseudogene

+-

+

+

Cell structure 

296

hisS

+

+

+

Translation, post-translational modification 

297

glyA

+

+

+

Amino acid biosynthesis and metabolism 

298

bioD

+

+

+-

Biosynthesis of cofactors, prosthetic groups and carriers

299

bioC

+

-

-

Biosynthesis of cofactors, prosthetic groups and carriers

300

bioF

+

-

-

Biosynthesis of cofactors, prosthetic groups and carriers

301

bioB

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

302

bioA

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

303

ybhE

+

+

+

Central intermediary metabolism 

304

mfd

+

+

+-

DNA replication, recombination, modification and repair 

305

ycfU

-

+

+

Hypothetical, unclassified, unknown 

306

ycfV

-

+

+

Hypothetical, unclassified, unknown 

307

ycfW

-

+-

+

Other known genes 

308

gapA

+

+

+

Energy metabolism 

309

yqcD

-

-

+

Hypothetical, unclassified, unknown 

310

fldA

+

+

+

Energy metabolism 

311

phrB

+

+

+-

DNA replication, recombination, modification and repair 

312

ybgI

+

+

+

Hypothetical, unclassified, unknown 

313

sucA

+

+

+

Energy metabolism 

314

sucB

+

+

+

Energy metabolism 

315

pal

+

-

-

Cell structure 

316

gpmA

+

+

+

Energy metabolism 

317

pfkA

+

+

+

Energy metabolism 

318

glpF

-

+

+

Transport and binding proteins 

319

tpiA

+

+

+

Energy metabolism 

320

himD

-

+

+

DNA replication, recombination, modification and repair 

321

rpsA

+

+

+

Translation, post-translational modification 

322

cmk

+

+-

+-

Nucleotide biosynthesis and metabolism 

323

aroA

+

+

+

Amino acid biosynthesis and metabolism 

324

serC

+

+

+

Amino acid biosynthesis and metabolism 

325

serS

+

+

+

Translation, post-translational modification 

326

trxB

+

+

+

Nucleotide biosynthesis and metabolism 

327

infA

+

+

+

Translation, post-translational modification 

328

aspS

+

+

+

Translation, post-translational modification 

329

znuB

+

+

+

Transport and binding proteins 

330

znuC

+

+

+

Transport and binding proteins 

331

znuA

-

-

+

Transport and binding proteins 

332

yebA

+

-

+

Cell structure 

333

pykA

+

+

+

Energy metabolism 

334

zwf

+

+

+

Energy metabolism 

335

htpX

+

+

+

Cell processes (incl. adaptation, protection) 

336

cspC

-

+

-

Transcription, RNA processing and degradation 

337

yoaE

+

+

+

Hypothetical, unclassified, unknown 

338

yeaZ

+

+

+

Hypothetical, unclassified, unknown 

339

minE

+

+

+

Cell processes (incl. adaptation, protection) 

340

minD

+

+

+

Cell processes (incl. adaptation, protection) 

341

minC

+

+

+

Cell processes (incl. adaptation, protection) 

342

yjjT

+

+

+

Transcription, RNA processing and degradation 

343

tRNA-Leu

+

+

+

RNAs 

344

tRNA--pseudo

+

+

+

RNAs 

345

tRNA-Ser

+

+

+

RNAs 

346

ompA

-

+

+

Cell structure 

347

mviN

+

+

+

Cell processes (incl. adaptation, protection) 

348

pyrC

-

+

+

Nucleotide biosynthesis and metabolism 

349

flgN

-

+

+

Cell processes (incl. adaptation, protection) 

350

flgA

-

+

+

Cell processes (incl. adaptation, protection) 

351

flgB

+

+

+

Cell processes (incl. adaptation, protection) 

352

flgC

+

+

+

Cell processes (incl. adaptation, protection) 

353

flgD

-

+

+

Cell processes (incl. adaptation, protection) 

354

flgE

-

+

+

Cell processes (incl. adaptation, protection) 

355

flgF

+

+

+

Cell processes (incl. adaptation, protection) 

356

flgG

+

+

+

Cell processes (incl. adaptation, protection) 

357

flgH

+

+

+

Cell processes (incl. adaptation, protection) 

358

flgI

+

+

+

Cell processes (incl. adaptation, protection) 

359

flgJ

+

+

+

Cell processes (incl. adaptation, protection) 

360

flgK

-

+

+

Cell processes (incl. adaptation, protection) 

361

rne

+

+

+

DNA replication, recombination, modification and repair 

362

rluC

+

+

+

Translation, post-translational modification 

363

rpmF

+

+

+

Translation, post-translational modification 

364

fabD

+

+-

+

Fatty acid and phospholipid metabolism 

365

fabG

+

+

+

Fatty acid and phospholipid metabolism 

366

acpP

+

+

+

Fatty acid and phospholipid metabolism 

367

tmk

+

+

+

Nucleotide biosynthesis and metabolism 

368

holB

+

+

+

DNA replication, recombination, modification and repair 

369

ycfH

+

+

+

Hypothetical, unclassified, unknown 

370

ptsG

+

+

+

Transport and binding proteins 

371

ycfF

+

+

+

Hypothetical, unclassified, unknown 

372

ycfM--pseudogene

+-

+

+-

Hypothetical, unclassified, unknown 

373

ompF

-

+

+

Cell structure 

374

asnS

+

+

+

Translation, post-translational modification 

375

pncB

-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

376

pyrD

-

+

+

Nucleotide biosynthesis and metabolism 

377

ycbY

-

+

+

Hypothetical, unclassified, unknown 

378

uup

-

+

+

Transport and binding proteins 

379

yceA

+

+

+

Hypothetical, unclassified, unknown 

380

valS

+

+

+

Translation, post-translational modification 

381

pepA

+

+

+

Translation, post-translational modification 

382

argF

+

+

+

Amino acid biosynthesis and metabolism 

383

pyrB

-

+

+

Nucleotide biosynthesis and metabolism 

384

pyrI

-

+

+

Nucleotide biosynthesis and metabolism 

385

yhaR

+

+

+

Hypothetical, unclassified, unknown 

386

deaD

+

+

+

Transcription, RNA processing and degradation 

387

pnp

+

+

+

Transcription, RNA processing and degradation 

388

rpsO

+

+

+

Translation, post-translational modification 

389

truB

+

+

+

Translation, post-translational modification 

390

rbfA

+

+

+

Translation, post-translational modification 

391

infB

+

+

+

Translation, post-translational modification 

392

nusA

+

+

+

Transcription, RNA processing and degradation 

393

tRNA-Leu


+

+

+ RNAs 

394

secG--pseudo

+-

+

+

Transport and binding proteins 

395

mrsA

+

+

+-

Central intermediary metabolism 

396

hflB

+

+

+

Cell processes (incl. adaptation, protection) 

397

ftsJ

+

+

+

Cell processes (incl. adaptation, protection) 

398

greA

+

+

+

Translation, post-translational modification 

399

yrbA

+

+

+

Hypothetical, unclassified, unknown 

400

murA

+

+

+

Cell structure 

401

rplU

+

+

+

Translation, post-translational modification 

402

rpmA

+

+

+

Translation, post-translational modification 

403

yhbZ

+

+

+

Other known genes 

404

rpsI

+

+

+

Translation, post-translational modification 

405

rplM

+

+

+

Translation, post-translational modification 

406

pheA

+

+

+

Amino acid biosynthesis and metabolism 

407

ffh

+

+

+

Transport and binding proteins 

408

rpsP

+

+

+

Translation, post-translational modification 

409

rimM

+

+

+

Other known genes 

410

trmD

+

+

+

Translation, post-translational modification 

411

rplS

+

+

+

Translation, post-translational modification 

412

tldD

+

+

+

Hypothetical, unclassified, unknown 

413

aroQ

+

+

+

Amino acid biosynthesis and metabolism 

414

fis

-

+

+

DNA replication, recombination, modification and repair 

415

rluD

+

+

+

Other known genes 

416

yfiO

-

+

+

Hypothetical, unclassified, unknown 

417

alaS

+

+

+

Translation, post-translational modification 

418

csrA

+

+

+

Regulatory function 

419

tRNA-Ser

+

+

+

RNAs 

420

tRNA-Arg

+

+

+

RNAs 

421

gshA

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

422

metK

-

+

+

Central intermediary metabolism 

423

endA

+

+

+-

Transcription, RNA processing and degradation 

424

yggJ

-

+

+

Hypothetical, unclassified, unknown 

425

ygfA

+

-

+

Biosynthesis of cofactors, prosthetic groups and carriers

426

rpiA

+

+

+

Energy metabolism 

427

tRNA-Gln

+

+

+

RNAs 

428

tRNA-Leu

+

+

+

RNAs 

429

tRNA-Met

+

+

+

RNAs 

430

glnS

+

+

+

Translation, post-translational modification 

431

pyrG

+

+

+

Nucleotide biosynthesis and metabolism 

432

eno

+

+

+

Energy metabolism 

433

ygcF

-

-

+

Hypothetical, unclassified, unknown 

434

ygcM

-

-

+

Hypothetical, unclassified, unknown 

435

nlpD

-

+

+-

Cell structure 

436

ygbB--pseudo

+-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

437

ygbP

+-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

438

ygbQ

-

+

+

Hypothetical, unclassified, unknown 

439

cysC

-

+

+

Central intermediary metabolism 

440

cysN

-

+

+-

Central intermediary metabolism 

441

cysD

-

+

+-

Central intermediary metabolism 

442

cysG

-

+

+-

Biosynthesis of cofactors, prosthetic groups and carriers

443

cysH

-

+

+-

Central intermediary metabolism 

444

cysI

-

+

+-

Central intermediary metabolism 

445

cysJ

-

+

+

Central intermediary metabolism 

446

mutS

+

+

+

DNA replication, recombination, modification and repair 

447

dsbA

+

+

+

Translation, post-translational modification 

448

polA

+

+

+

DNA replication, recombination, modification and repair 

449

yihA

+

+

+

Hypothetical, unclassified, unknown 

450

typA

+

+

+

Other known genes 

451

gmk

+

+

+

Nucleotide biosynthesis and metabolism 

452

thyA

+

+

+

Nucleotide biosynthesis and metabolism 

453

lgt

+

+

+-

Fatty acid and phospholipid metabolism 

454

lysA

+

+

+

Amino acid biosynthesis and metabolism 

455

lysS

+

+

+

Translation, post-translational modification 

456

prfB

+

+

+-

Translation, post-translational modification 

457

ygfZ

+

+

+

Hypothetical, unclassified, unknown 

458

yleA

+

+

+

Hypothetical, unclassified, unknown 

459

ybeY

+

+

+

Hypothetical, unclassified, unknown 

460

ybeX

+

+

+

Transport and binding proteins 

461

leuS

+

+

+

Translation, post-translational modification 

462

holA

+

+

+

DNA replication, recombination, modification and repair 

463

ybeN

-

+

+

Hypothetical, unclassified, unknown 

464

yhhP

+

+

+

Hypothetical, unclassified, unknown 

465

asd

+

+

+

Amino acid biosynthesis and metabolism 

466

yhgN

+

+

+

Hypothetical, unclassified, unknown 

467

pgk

+

+

+

Energy metabolism 

468

fba

+

+

+

Energy metabolism 

469

yggB

+

+

+

Transport and binding proteins 

470

recC

+

+

+

Transcription, RNA processing and degradation 

471

recB

+

+

+

Transcription, RNA processing and degradation 

472

recD

+

+

+

Transcription, RNA processing and degradation 

473

argA

-

+

+

Amino acid biosynthesis and metabolism 

474

tRNA-Met

+

+

+

RNAs 

475

mltA

-

+

+

Cell structure 

476

ribH

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

477

thiL

-

+

+

Other known genes 

478

ribD

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

479

nusB

+

+

+

Transcription, RNA processing and degradation 

480

dxs--pseudogene

+-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

481

ispA

-

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

482

yajR

+

+

+

Transport and binding proteins 

483

yccK

+

+

+

Central intermediary metabolism 

484

cyoE

+

+

+

Energy metabolism 

485

cyoD

+

+

+

Energy metabolism 

486

cyoC

+

+

+

Energy metabolism 

487

cyoB

+

+

+

Energy metabolism 

488

cyoA

+

+

+

Energy metabolism 

489

bolA

+

+

+

Cell structure 

490

tig

-

+

+

Cell processes (incl. adaptation, protection) 

491

clpP

+

+

+

Translation, post-translational modification 

492

clpX

+

+

+

Translation, post-translational modification 

493

lon

+

+

+

Regulatory function 

494

ppiD

+

+

+

Cell processes (incl. adaptation, protection) 

495

ybaX

-

-

+

Hypothetical, unclassified, unknown 

496

mdl

+

+

+

Transport and binding proteins 

497

mdlB

+

+

+

Transport and binding proteins 

498

dnaX

+

+

+

DNA replication, recombination, modification and repair 

499

ybaB

+

+

+

Hypothetical, unclassified, unknown 

500

htpG

+

+

+

Cell processes (incl. adaptation, protection) 

501

adk

+

+

+

Nucleotide biosynthesis and metabolism 

502

tRNA-Arg

+

+

+

RNAs 

503

folD

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

504

cysS

+

+

+

Translation, post-translational modification 

505

ybeD

+

+

+

Hypothetical, unclassified, unknown 

506

cspE

+

+

+

Other known genes 

507

rrs-5S rRNA

+

+

+

RNAs 

508

rrl-23S rRNA

+

+

+

RNAs 

509

tRNA-Glu

+

+

+

RNAs 

510

aroE

+

+

+

Amino acid biosynthesis and metabolism 

511

yrdC

+

+

+

Hypothetical, unclassified, unknown 

512

smg

-

+

+

Hypothetical, unclassified, unknown 

513

def

+

+

+

Translation, post-translational modification 

514

fmt

+

+

+

Translation, post-translational modification 

515

rplQ

+

+

+

Translation, post-translational modification 

516

rpoA

+

+

+

Transcription, RNA processing and degradation 

517

rpsD

+

+

+

Translation, post-translational modification 

518

rpsK

+

+

+

Translation, post-translational modification 

519

rpsM

+

+

+

Translation, post-translational modification 

520

rpmJ

+

+

+

Translation, post-translational modification 

521

secY

+

+

+

Transport and binding proteins 

522

rplO

+

+

+

Translation, post-translational modification 

523

rpmD

+

+

+

Translation, post-translational modification 

524

rpsE

+

+

+

Translation, post-translational modification 

525

rplR

+

+

+

Translation, post-translational modification 

526

rplF

+

+

+

Translation, post-translational modification 

527

rpsH

+

+

+

Translation, post-translational modification 

528

rpsN

+

+

+

Translation, post-translational modification 

529

rplE

+

+

+

Translation, post-translational modification 

530

rplX

+

+

+

Translation, post-translational modification 

531

rplN

+

+

+

Translation, post-translational modification 

532

rpsQ

+

+

+

Translation, post-translational modification 

533

rpmC

+

+

+

Translation, post-translational modification 

534

rplP

+

+

+

Translation, post-translational modification 

535

rpsC

+

+

+

Translation, post-translational modification 

536

rplV

+

+

+

Translation, post-translational modification 

537

rpsS

+

+

+

Translation, post-translational modification 

538

rplB

+

+

+

Translation, post-translational modification 

539

rplW

+

+

+

Translation, post-translational modification 

540

rplD

+

+

+

Translation, post-translational modification 

541

rplC

+

+

+

Translation, post-translational modification 

542

rpsJ

+

+

+

Translation, post-translational modification 

543

tuf

+

+

+

Translation, post-translational modification 

544

fusA

+

+

+

Translation, post-translational modification 

545

rpsG

+

+

+

Translation, post-translational modification 

546

rpsL

+

+

+

Translation, post-translational modification 

547

yheL

+

+

+

Hypothetical, unclassified, unknown 

548

yheM

+

+

+

Hypothetical, unclassified, unknown 

549

yheN

+

+

+

Hypothetical, unclassified, unknown 

550

fkpA

+

+

+

Translation, post-translational modification 

551

argD

-

+

+

Amino acid biosynthesis and metabolism 

552

yhfC

+

+

+

Transport and binding proteins 

553

trpS

+

+

+

Translation, post-translational modification 

554

rpe

+

+

+

Energy metabolism 

555

aroB

+

+

+

Amino acid biosynthesis and metabolism 

556

aroK

+

+

+

Amino acid biosynthesis and metabolism 

557

tRNA-Ser

+

+

+

RNAs 

558

deoD

+

+

+

Nucleotide biosynthesis and metabolism 

559

deoB

+

+

+

Nucleotide biosynthesis and metabolism 

560

prfC

+

+

+

Translation, post-translational modification 

561

ansA

-

+-

+-

Amino acid biosynthesis and metabolism 

562

yhgI

+

+

+

Hypothetical, unclassified, unknown 

563

bioH

+

-

+-

Biosynthesis of cofactors, prosthetic groups and carriers

564

ssb

+

+

+

DNA replication, recombination, modification and repair 

565

dnaB

+

+

+

DNA replication, recombination, modification and repair 

566

gshB

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

567

yqgE

+

-

-

Transcription, RNA processing and degradation 

568

yqgF

+

+

+

Hypothetical, unclassified, unknown 

569

leuA

+

+

+

Amino acid biosynthesis and metabolism 

570

leuB

+

+

+

Amino acid biosynthesis and metabolism 

571

leuC

+

+

+

Amino acid biosynthesis and metabolism 

572

leuD

+

+

+

Amino acid biosynthesis and metabolism 

573

yggS

+

+

+

Hypothetical, unclassified, unknown 

574

yggW

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

575

yggH

+

+

+

Hypothetical, unclassified, unknown 

576

mutY

+

+

+

DNA replication, recombination, modification and repair 

577

yggX

+

+

+

Hypothetical, unclassified, unknown 

578

murI

+

+

+

Cell structure 

579

sbcB

+

+

+

Transcription, RNA processing and degradation 

580

yeeX

-

+

+

Hypothetical, unclassified, unknown 

581

tRNA-Asn

+

+

+

RNAs 

582

tRNA-Met

+

+

+

RNAs 

583

pyrE

+

+

+-

Nucleotide biosynthesis and metabolism 

584

dut

+

+

+

Nucleotide biosynthesis and metabolism 

585

cysQ

-

+

+-

Central intermediary metabolism 

586

rplI

+

+

+

Translation, post-translational modification 

587

rpsR

+

+

+

Translation, post-translational modification 

588

rpsF

+

+

+

Translation, post-translational modification 

589

vacB

-

+

+

Hypothetical, unclassified, unknown 

590

purA

+

+

+

Nucleotide biosynthesis and metabolism 

591

hflC

+

+

+

Translation, post-translational modification 

592

hflK

+

+

+

Translation, post-translational modification 

593

miaA

+

+

+-

Translation, post-translational modification 

594

mutL

+

+

+

DNA replication, recombination, modification and repair 

595

mtlD

+

+

+

Energy metabolism 

596

mtlA

+

+

+

Transport and binding proteins 

597

pgi

+

+

+

Energy metabolism 

598

orn

+

+

+

Other known genes 

599

tRNA-Gly

+

+

+

RNAs 

600

amiB

+

+

+

Cell structure 

601

rpmE

+

+

+

Translation, post-translational modification 

602

hslV

+

+

+

Translation, post-translational modification 

603

hslU

+

+

+

Cell processes (incl. adaptation, protection) 

604

trpG

+

+

+

Amino acid biosynthesis and metabolism 

605

trpE

+

+

+

Amino acid biosynthesis and metabolism 

606

ibpA

-

+

+

Cell processes (incl. adaptation, protection) 

607

fpr

+

+

+

Energy metabolism 

608

yjeA

+

+

+-

Translation, post-translational modification 

609

kdtB

-

+

+

Cell structure 

610

yba3

+

+

+-

Hypothetical, unclassified, unknown 

611

yba4

-

+

+

Hypothetical, unclassified, unknown 

612

uspA

+

-

-

Cell processes (incl. adaptation, protection) 

613

yhiQ

-

+

+

Hypothetical, unclassified, unknown 

614

pitA

+

+

+

Transport and binding proteins 

615

ynfM

+

+

+

Transport and binding proteins 

616

dapF

+

+

+

Amino acid biosynthesis and metabolism 

617

cyaY

+

+

+

Hypothetical, unclassified, unknown 

618

hemC

-

+

+-

Biosynthesis of cofactors, prosthetic groups and carriers

619

hemD

-

+-

+-

Biosynthesis of cofactors, prosthetic groups and carriers

620

tRNA-Pro

+

+

+

RNAs 

621

tRNA-His

+

+

+

RNAs 

622

tRNA-Arg

+

+

+

RNAs 

623

rho

+

+

+

Transcription, RNA processing and degradation 

624

trxA

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

625

rep

+

+

+

DNA replication, recombination, modification and repair 

626

ilvC

+

+

+

Amino acid biosynthesis and metabolism 

627

ilvD

+

+

+

Amino acid biosynthesis and metabolism 

628

tRNA-Trp

+

+

+

RNAs 

629

yfhO

+

+

+

Biosynthesis of cofactors, prosthetic groups and carriers

630

iscU

+

+

+

Other known genes 

631

hscB

+

+

+

Cell processes (incl. adaptation, protection) 

632

hscA

+

+

+

Cell processes (incl. adaptation, protection) 

633

fdx

+

+

+

Energy metabolism 

634

yfgK

+

+

+

Other known genes 

635

yfgM

+

+

+

Hypothetical, unclassified, unknown 

636

repA1

+

+

+

DNA replication, recombination, modification and repair 

637

yqhA

+

+

+

Hypothetical, unclassified, unknown 

638

repA2

+

+

+

DNA replication, recombination, modification and repair