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Robert Hoffmann, PhD
Chris Sander's Lab
Computational Biology Center, cBIO.
Memorial Sloan-Kettering Cancer Center, MSKCC.
1275 York Avenue. New York, NY 10021.
phone +1 646-735-8081, fax +1 646-735-0021
hoffmann@cbio.mskcc.org

curriculum vitae

 

qualifications
2001   2005   PhD, National Center of Biotechnology (CNB), Madrid / Institute for Theoretical Chemistry, University of Vienna
1998 / 1999   Master, Institute of Molecular Pathology, Boehringer Ingelheim, Austria / Institute for Theoretical Chemistry, University of Vienna
1997 / 1998   Performance scholarship
1994 - 1998   Genetics, University of Vienna
1991 / 1992   Student exchange program, Canada
1985 - 1993   Secondary school, Vienna

professional development
2005   -   PostDoc at the MSKCC
2001   2005   PHD program at the National Center of Biotechnology (CNB)
2000       Independent IT-consultant and software developer
1999       Development and implementation of tools and algorithms (Java and C++) for the administration and analysis of microarray experiments at the Institute of Molecular Pathology, Boehringer Ingelheim (IMP), Austria
1998 / 1999   Diploma thesis in the area of structural bioinformatics at the Institute for Theoretical Chemistry and Molecular Structural Biology headed by Dr. Peter Schuster; "The importance of short structural motifs in protein structure analysis".
1997       Practical training; Development of an application for the administration of clones and restriction maps, "CloneMap"; Biochemical Institute, Vienna

publications
Implementing the iHOP concept for navigation of biomedical literature. Hoffmann, R., Valencia, A. Bioinformatics 21(suppl. 2), ii252-ii258 (2005). PDF , Suppl. Mat., Online Version
Text mining for metabolic pathways, signaling cascades, and protein networks. Hoffmann, R., Krallinger, M., Andres, E, Tamames, J., Blaschke, C., Valencia, A. Sci STKE 283, 21 (2005). , PDF
HCAD, closing the gap between breakpoints and genes. Hoffmann, R., Dopazo, J., Cigudosa, J.C., Valencia, A. Nucleic Acids Research 33, D511-3 (2005). , PDF
A gene network for navigating the literature. Hoffmann, R., Valencia, A. Nature Genetics 36, 664 (2004). , PDF
Protein interaction: same network, different hubs. Hoffmann, R., Valencia, A. Trends Genet. 19(12), 681-683. (2003). , PDF

Life cycles of successful genes. Hoffmann, R., Valencia, A. Trends Genet. 19(2), 79-81. (2003). , PDF

TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells. Vietor, I., Vadivelu, S. K., Wick, N., Hoffmann, R., Cotten, M. et al. Embo J 21, 4621-31 (2002). , PDF
Extracting information automatically from the biological literature. Blaschke, C., Hoffmann, R., Oliveros, J.C. and Valencia, A. Comp. Funct. Genom. (2), 310-313. (2001). PDF
The importance of short structural motifs in protein structure analysis; Diploma thesis at the Institute for Theoretical Chemistry and Molecular Structural Biology, University of Vienna (1999).
 
posters
iHOP: A gene network for navigating PubMed. Hoffmann, R., Valencia, A. ISMB(ECCB (2004)
Transcriptional control of epithelial cell polarity and motility by TIS7. Wick, N., Vietor, I., Cotten, M., Bister, M., Hoffmann, R., Beyer, A., Zatloukal, K., Huber, L. A. Poster at the I.M.P. Recess (2000).
Analysis of TIS7 Effects on Epithelial Cell Morphology and Gene Expression. Wick, N., Hoffmann, R., Vietor, I., Cotten, M., Paiha, K., Huber, L. A. Poster at the I.M.P. Recess (1999).
 
conferences
iHOP. E-BioSci/ORIEL Annual Workshop. Cambridge, UK (2004)
Navigating PubMed. E-BioSci/ORIEL Annual Workshop. Varenna, Italy (2003)
Text discovery tools. Application to cancer research. Leuven, Belgium (2002)
Mining the Biomedical Literature. ISMB tutorial (2001)
 
languages
English, German, Spanish

programming skills    
object oriented languages   Java, C++
data exchange   XML, XSL
scripting languages   HTML, JavaScript, Perl
database design   Postgres, Oracle, SQL, jdbc
server-side   JSP, XSP, Tomcat, Cocoon
operating systems   Unix, Linux, win
statistical analysis   R, spss, splus