Nuclc. Acids. Res. OUP
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WILMA

http://www.came.sbg.ac.at/wilma/

Prlic, A., Domingues, F.S., Lackner, P., Sippl, M.J.

Center of Applied Molecular Engineering Institute for Chemistry and Biochemistry University of Salzburg Jakob-Haringerstr. 3 A-5020 Salzburg AUSTRIA

Contact   wilma@came.sbg.ac.at


Database Description

WILMA is a genome and proteome annotation system that integrates biological data bases, annotation tools and data base techniques. WILMA's objective is to provide a comprehensive description of genes, gene products, and entire genomes. WILMA consists of an automated annotation process for the integration of genomic and proteomic sequence data bases with secondary data bases like PROSITE, BLOCKS, PFAM, and SMART and descriptors for molecular function, biological processes and cellular components, as defined by Gene Ontology (GO). The annotation process employs search methods like BLAST, RPS-BLAST, BLIMPS, PROSITE scans, and a transmembrane region predictor. The corresponding data is stored in a relational database. WILMA provides access to this data base via web-interfaces and data base queries. In the development of WILMA we used the genome of the multicellular nematode C.elegans as a pilot study. Other genomes will follow.

Acknowledgements

Support for this work was provided by the Fonds zur Forderung der wissenschaftlichen Forschung, Austria; grant number P13710-MOB.

REFERENCES

  1. http://www.geneontology.org/
  2. http://www.ebi.ac.uk/interpro/
  3. http://www.sanger.ac.uk/Projects/C_elegans/wormpep/
  4. http://www.expasy.ch/prosite/
  5. http://blocks.fhcrc.org/blocks/
  6. http://www.sanger.ac.uk/Software/Pfam/
  7. http://smart.embl-heidelberg.de/
  8. http://www.ncbi.nlm.nih.gov/BLAST/

Category   Genomic Databases

 

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