Go to the abstract in the NAR 2001 Database Issue.
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Cooper, C., Harrison, M., Webster, J., Wilkins, M., Packer, N.
Proteome Systems Ltd Locked Bag 2073 North Ryde, Sydney, NSW 1670 Australia
GlycoSuiteDB release 2.0, September 2001, contained more than 6600 annotated entries of glycan structures derived from glycoproteins, or free oligosaccharides isolated from biologically important fluids such as milk, saliva and urine. For each structure information is available concerning the glycan type, linkage and anomeric configuration, mass and composition. Detailed information is provided on native and recombinant sources, including species, tissue and/or cell type, cell line, strain, blood group and disease state. There are more than 870 different biological sources represented in GlycoSuiteDB, from over 200 different tissue or cell types. Where known, the proteins to which the glycan structures are attached are described, and cross-references to SWISS-PROT are given if applicable. The database annotations include literature references which are linked to PubMed, and detailed information on the methods used to determine each glycan structure, to help the user assess the quality of the structural assignment. The web site (www.glycosuite.com) allows the user to search the database using a combination of composition, glycan linkage type, reducing-terminal sugar residue, glycan mass (monoisotopic or average), species, biological system, tissue or cell type, disease state, protein name, SWISS-PROT/TrEMBL accession number, or reference information. Results can be sorted by glycan mass, protein name, tissue or cell type, disease state or taxonomy. The emphasis of this database is to be consistent. This will enable reliable mining of the information for future applications of glycobiology.
We have updated the reference citations to include all authors and full titles. This has enabled us to introduce queries by reference, where the user may query the database using authors names and/or publication years. We have also updated the disease state field to be more consitent and have subsequently enabled queries by disease state. Users must now register and receive a password to gain access to the detailed entries. There are still no restrictions on its use by non-profit organisations as long as its content is not modified in any way. Usage by and for commercial entities requires a license agreement.
We thank Jo Packer, Hiren Joshi and Sarah Jarvis for their continued hard work on this database.
Category Varied Biomedical Content
Go to the abstract in the NAR 2001 Database Issue.