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Gene Resource Locator

http://grl.gi.k.u-tokyo.ac.jp

Honkura, T.1, Ogasawara, J.2, Yamada, T.1, Morishita, S.1

1Department of Complexity Science and Engineering, Faculty of Frontier Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JAPAN
2Department of Computer Science, Faculty of Information Science and Technology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JAPAN

Contact   honkura@gi.k.u-tokyo.ac.jp


Database Description

The GRL (Gene Resource Locator) database offers an integrated and annotated genomic map. To date, the database contains 2.2 million alignments (exon-intron structures), computed using our own software and having 90% or higher identity with the human draft genome. The novel aspect of our database is that we have further processed these alignments to develop a new type of annotation that encompasses approximately 90,000 EST loci sharing common exons, 8,091 alternatively spliced transcript groups, 10,801 expression profile groups, 8,066 candidate regulatory regions in full-length cDNAs, more than 500 processed pseudogenes, and a million SNP loci. In order to facilitate browsing through millions of alignments, we have used Flash technology to build a dynamic web viewer. All of the above information is available through the WWW at the Gene Resource Locator (http://grl.gi.k.u-tokyo.ac.jp).

Acknowledgements

Special thanks go to Jun Sese for helping us build the GRL server. We are also grateful to Prof. Kousaku Okubo at Osaka Univ., Prof. Sumio Sugano at IMS, Univ. Tokyo, and James Kent at UCSC for their stimulus input. The Gene Resource Locator is supported by Grant#12208003 Grant-in-Aid for Scientific Research on Priority Areas from the Ministry of Education, Science, and Culture Japan.

REFERENCES

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Category   Gene Identification and Structure

Go to the abstract in the NAR 2002 Database Issue.

 

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