Mycobacterium tuberculosis

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Species: Mycobacterium tuberculosis

Species code: MYCTU

Type: Eubacteria

Taxonomy: Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium (TaxID: 1773) [NEWT / NCBI]

Strain(s): H37Rv and CDC 1551 / Oshkosh

Genome: circular, 4.41 Mb; no ECE

Reference(s): STRAIN=H37Rv;
MEDLINE=98295987 [NCBI, ExPASy, Israel, Japan]; PubMed=9634230;
Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G.;
"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.";
Nature 393:537-544(1998).

STRAIN=CDC 1551 / Oshkosh;
Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M.L., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T., Weidman J., Khouri H., Gill J., Mikula A., Bishai W.;
"Whole genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.";
Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.

Genome official sequence WWW site(s): http://www.sanger.ac.uk/Projects/M_tuberculosis/
http://www.tigr.org/tigr-scripts/CMR2/GenomePage3.spl?database=gmt

Other WWW site(s): TubercuList (H37Rv)
GIB (DDBJ) (H37Rv)
GIB (DDBJ) (CDC1551)
TIGR CMR (H37Rv)
EBI GeneQuiz (H37Rv)
Structural genomics
Secreted proteins

Description: Acid-fast, obligate aerobic, non-motile, rod-shaped bacterium. It is responsible for tuberculosis. Tuberculosis is, to this day, according to the WHO, the leading killer of adults. This is especially the case in HIV-positive individuals. Drug resistant strains are emerging mainly because people do not complete their treatment plans or have been incorreclty treated and so have remained infectious.

Properties: Number of membranes : 1
Presence of a flagella : No
Number of inteins : 3 in 3 different sequences

Genomic Proximity Viewer
Proteome analysis at EBI
Perform a BLAST search against all proteins from Mycobacterium tuberculosis
Download ftp file containing all Swiss-Prot and TrEMBL entries of this organism
- in Swiss-Prot format
- in FASTA format

Last modified 12-Apr-2003

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Species:	Mycobacterium tuberculosis
Species code:	MYCTU
Type:	Eubacteria
Taxonomy:	Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium (TaxID: 1773) [NEWT / NCBI]
Strain(s):	H37Rv and CDC 1551 / Oshkosh
Genome:	circular, 4.41 Mb; no ECE
Reference(s):	STRAIN=H37Rv; MEDLINE=98295987 [NCBI, ExPASy, Israel, Japan]; PubMed=9634230; Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G.; "Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence."; Nature 393:537-544(1998).
	STRAIN=CDC 1551 / Oshkosh; Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M.L., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T., Weidman J., Khouri H., Gill J., Mikula A., Bishai W.; "Whole genome comparison of Mycobacterium tuberculosis clinical and laboratory strains."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Genome official sequence WWW site(s):	http://www.sanger.ac.uk/Projects/M_tuberculosis/ http://www.tigr.org/tigr-scripts/CMR2/GenomePage3.spl?database=gmt
Other WWW site(s):	TubercuList (H37Rv) GIB (DDBJ) (H37Rv) GIB (DDBJ) (CDC1551) TIGR CMR (H37Rv) EBI GeneQuiz (H37Rv) Structural genomics Secreted proteins
Description:	Acid-fast, obligate aerobic, non-motile, rod-shaped bacterium. It is responsible for tuberculosis. Tuberculosis is, to this day, according to the WHO, the leading killer of adults. This is especially the case in HIV-positive individuals. Drug resistant strains are emerging mainly because people do not complete their treatment plans or have been incorreclty treated and so have remained infectious.
Properties:	Number of membranes : 1 Presence of a flagella : No Number of inteins : 3 in 3 different sequences