- June 6, 1997
We are actively seeking any type of updates and/or corrections of SWISS-PROT entries, whether they have been
published or not, and we encourage our users to submit us their suggested
updates or corrections. This can be done using our new submission form, which can be accessed through an active link
from the SWISS-PROT home page or from
the bottom of each SWISS-PROT entry. Please read the tips and guidelines to find out what type of information we are
seeking and how to proceed.
We would already like to thank our users in advance for any contribution
they can make in updating and correcting SWISS-PROT!
The tool which allows you to visualize and highlight the subsequence corresponding
to a line in a SWISS-PROT feature table (FT) has been improved and is now
using colour to highlight the subsequences in question.
Example: in FA9_HUMAN:
FT DOMAIN 93 129 EGF-LIKE 1, CALCIUM-BINDING (POTENTIAL).
- May 21, 1997
- At the bottom of each page displaying a SWISS-PROT entry, you will now
find a link to a graphical Feature Table viewer (Java Applet) written by
Thomas Junier at the Bioinformatics Group of ISREC Lausanne.
- We have added several new hyperlinks in SWISS-PROT entries:
- The DR lines containing cross-references to EMBL/GenBank/DDBJ now include
a link to a page displaying exclusively the corresponding CoDing Sequence (CDS).
- The RL lines referring to recent articles in certain journals whose WWW
servers are maintained in collaboration with HighWire Press are now active hyperlinks
to the abstracts of the corresponding articles.
From the abstract page you can frequently
access directly a full text on-line version of the article. The journals
J. Biol. Chem., Proc. Natl. Acad. Sci. USA, Science, Cell, etc.
- Entries with cross-references to MIM are now also linked (through a new virtual
"DR GeneCards" line) to GeneCards,
a database integrating information about the functions of human genes and their
products, and of biomedical applications based on this knowledge.
- Entries belonging to family 1 of G-protein coupled receptors
(as documented in feature tables) now contain active links to GPCRDB-Snakes
diagrams (through the new virtual "DR GPCRDB-Snakes" line) prepared by the
GPCRDB group at EMBL Heidelberg.
- There are 3 new SWISS-PROT documents:
- humchr19.txt: an index of protein sequence entries encoded on human chromosome 19
- ngr234.txt: a table of putative genes in Rhizobium plasmid pNGR234a
- initfact.txt: a list of translation initiation factors
- On the ExPASy anonymous FTP server,
the SWISS-PROT update files new_seq.dat, upd_ann.dat and upd_seq.dat are
now also available in compressed form in the directory /ftp/databases/swiss-prot/updates_compressed/.
- March 27, 1997
We have modified and improved access from ExPASy to various BLAST
(Basic Local Alignment Search Tool) similarity search services:
In the tools page, you can now choose between 5 different interfaces
to BLAST servers in Switzerland, the USA and Germany:
- Running on a 2-processor Pentium Pro machine, the new WU-BLAST server at
EMBNet Switzerland in Lausanne has a faster response time than the EPFL
server, and should be more stable. As opposed to the original NCBI BLAST
algorithm, WU-BLAST generates gapped alignments. A full set of weekly updated
databases is provided.
- Local interface to WU-BLAST at EMBNet-CH (Lausanne)
- Original interface to WU-BLAST at EMBNet-CH (Lausanne)
- Local interface to BLAST at NCBI
- Original interface of BLAST at NCBI
- WU-BLAST at Bork's group in EMBL (Heidelberg)
For direct BLAST submission from a SWISS-PROT entry (icons at the bottom
of the page displaying an entry - example), you have the choice between the servers at NCBI and EMBNet-CH.
The following documents have been added to the list of SWISS-PROT documents:
- bloodgrp.txt - Blood group antigen proteins
- fly.txt - Index of Drosophila entries and their corresponding FlyBase cross-references
- mjannasc.txt - Index of Methanococcus jannaschii entries
- mgenital.txt - Index of Mycoplasma genitalium strain G-37 chromosomal entries
- March 17, 1997
We have completely rewritten the Swiss-Shop sequence alerting system
for SWISS-PROT that allows you to automatically obtain (by email) new
sequence entries relevant to your field(s) of interest.
In the new version of Swiss-Shop, some new features have been added:
As before, you can either launch a sequence/pattern based search
or a keyword based search.
- For a sequence based search, you need to specify a SWISS-PROT ID or AC or
a raw protein sequence, and your sequence will be scanned, at each
weekly update of SWISS-PROT, against the new sequences in the database
using the alignment program BLAST.
Sequences thus found to be similar to your protein will be sent to you
by email. It is up to you to specify the BLAST probability threshold
for P(N) (the probability that the alignment is real and not random),
and you will receive a list of all sequences for which this probability
is below the specified value.
- For a pattern based search, enter a PROSITE ID or AC or a pattern in
PROSITE format, and Swiss-Shop will scan this pattern, at each weekly
update of SWISS-PROT, against the sequences that have been added in
SWISS-PROT since the last weekly update. You will receive the list of new
entries matching your pattern.
- For a keyword based search, it was previously possible to specify keywords
from SWISS-PROT OS, OC, OG (taxonomy), RA (authors), KW, DE, CC lines.
In addition to these lines, you can now also search DR (Cross-references
to other databases) and FT (feature) lines with one or more specified
keywords. Swiss-Shop will look for these keywords on the corresponding
lines of all SWISS-PROT entries added in the database since the last
Furthermore, we now offer you 4 different output formats. You can choose
to receive the sequences matching your query
You can further specify if you wish to be notified every time Swiss-Shop
is run, even if there are no new sequences matching your query, or
to receive an email report only when there are new SWISS-PROT entries
matching your search terms.
- as a file in SWISS-PROT format or
- as a list of SWISS-PROT accession numbers or
- in form of a short report containing information from SWISS-PROT ID, AC,
DE, OS lines or
- as a list of SWISS-PROT accession numbers with hypertext links to the
corresponding entries on the ExPASy WWW server. This allows you to view
your email message with your Web browser and to follow the hypertext
links to the full entries on ExPASy.
You can specify the expiration date of your request, the default being
one year after submission.
For editing previous requests (e.g. to update the expiration date
or to modify search criteria) you can enter a password for each
new request. This allows you to open the request later and edit it
on-line rather than deleting it and submitting a new one.
- March 6, 1997
New and improved protein identification tools:
There is a new tool on ExPASy:
This tool achieves protein identification using parameters such as
protein species, estimated pI and MW, AA composition, sequence tag, and
peptide mass fingerprinting data. It
is particularly suited to the identification of proteins across species
Currently, the program works by first generating a set of proteins in the
database with AA compositions close to the unknown protein, as for
AACompIdent. Theoretical peptide masses from the proteins in this set
are then matched with the peptide masses of the unknown protein to
find the number of peptides in common (number of "hits"). Three types of
lists are produced in the results. Firstly, a list where proteins from
the database are ranked according to their AA composition score; secondly,
a list where proteins are ranked according to the number of peptide hits
they showed with the unknown protein; and thirdly, a list that shows only
proteins that were present in both the above lists, where these proteins
are ranked according to an integrated AA and peptide hit score. In all
these lists, protein pI, MW, and species of origin (using a term from
SWISS-PROT OS or OC lines) and keywords can be used, as in
AACompIdent, to increase the specificity of searches.
The following tools have been improved,
offering numerous additional features:
(identification of a protein from its amino acid composition)
You can restrict your search by specifying one or more term(s) from
the OS or OC lines of SWISS-PROT (example: HOMO SAPIENS or MAMMALIA).
You can also enter a keyword appearing on the KW lines of SWISS-PROT to
further restrict your search. For example, a keyword of "CALCIUM-BINDING" could
be used in conjunction with the OC term "MAMMALIA" to see if a user-
entered protein matches well with any mammalian calcium-binding proteins in the
- TagIdent now allows, for one or more species
(term from SWISS-PROT OS or OC lines) and with an optional keyword,
1. the generation of a list of proteins close to a given pI and Mw,
2. the identification of proteins by matching a short sequence tag of up
to 6 amino acids against proteins in the SWISS-PROT database close to
a given pI and Mw,
3. the identification of proteins by their mass, if this mass has been
determined by mass spectrometric techniques.
AACompSim and all the above-mentioned tools,
documentation and references have been added and the
submission forms have been reformatted and improved.
- March 4, 1997
Thanks to the generosity of the Geneva Government, we have been able to
acquire a new computer for the ExPASy server (a Sun Microsystems
Ultra Server Enterprise 2). The server is now accessible at URL:
The old URL remains valid for some time.
- January 9, 1997
Some new features of ExPASy:
- November 26, 1996
The Boehringer Mannheim Biochemical Pathways
maps and index have been digitised and are now accesible on this server.
Enter a keyword (such as, for example Oxoacyl) and surf on the biochemical pathways maps.
- November 11, 1996
CD40Lbase, The European CD40L Defect Database prepared by Manuel Peitsch,
has been made accessible through this server. The purpose of
CD40Lbase is to collect clinical and molecular data on CD40 ligand defects
leading to X-linked Hyper-IgM syndrome.
A new tool is available from the Tools page:
The PeptideMass Peptide
This program is designed to calculate the theoretical masses of peptides generated by the chemical or enzymatic
cleavage of proteins, to assist in the interpretation of peptide mass fingerprinting and peptide mapping experiments.
Protein sequences can be provided by the user or can be a code name for a protein in the SWISS-PROT protein
database. When proteins of interest are specified from SWISS-PROT, the program considers all annotations
for that protein in the database, and uses these in order to generate the correct peptide masses and warn
users about peptides that are not likely to be found when undertaking peptide mass fingerprinting. Many protein
post-translational modifications which affect the masses of peptides can thus be taken into consideration.
In PROSITE and Enzyme,
we have added the possibility to save all referenced SWISS-PROT entries
to a file on our anonymous FTP server
(in the outgoing
The Compute pI/Mw tool has been included
in the list of sequence analysis tools that can be directly accessed from a SWISS-PROT entry.
Two new SWISS-PROT documents are available:
- an index of protein sequence entries encoded on human chromosome 20
- a list of the currently valid values for the "TISSUE" topic of the
RC line type in SWISS-PROT.
- September 30, 1996
A new SWISS-PROT document has been added:
ribosomp.txt - an index of
ribosomal proteins classified by families on the basis of sequence
In ec2dtosp.txt, an index of E.
coli Gene-protein database (ECO2DBASE) entries referenced in SWISS-PROT, we have established direct links to ECO2DBASE, and
SWISS-PROT entries now also contain links to ECO2DBASE.
At the end of each page displaying a SWISS-PROT entry we have added
links to our sequence analysis tools ProtParam and ProtScale,which allows
the user to directly submit the SWISS-PROT sequence to these tools.
- September 19, 1996
Some new features of ExPASy:
- April 11, 1996
New options - AACompIdent is a tool which allows the
identification of a protein from its
amino acid composition. It searches SWISS-PROT for proteins, whose amino
acid compositions are closest to the amino acid composition given. Two
new options and a new constellation have been added to this tool:
A. C-Terminal display in tagging option
The user may now choose between displaying the C or N terminal side
of the proteins that score best.
B. Permutation search in tagging option
This option searches for all permutations of the given tag in the sequences.
C. Constellation 4
Constellation 4 has been added: Ala, Ile, Pro, Val, Arg, Leu, Ser, Asx, Lys, Thr, Glx, Met, His, Phe and Tyr.
(Asp+Asn=Asx; Gln+Glu=Glx; Gly, Cys and Trp are not considered).
- March 22, 1996
We have added a new tool, ProtScale which
allows you to compute and represent the profile produced by an amino acid scale
on a selected protein. 50 scales are provided, including 'classics' such
as the Kyte and Doolittle hydrophobicity scale.
Links have been added between relevant SWISS-PROT entries and the 2D
gel protein databases at
A new SWISS-PROT document has been added which describes the nomenclature of
glycosyl hydrolases (GH) and that
includes an index of sequences that belong to the various GH families.
A PC (MS-Windows) version of LALNVIEW
(graphical viewer for pairwise alignments) is now
Nicolas Guex has produced a new
logo for PROSITE.
- February 16, 1996
We have added a new tool, SIM which
computes a user defined number of best non-intersecting alignments between two
sequences. The results of the alignment can be viewed graphically using the
program developed by Laurent Duret and
which is currently available
for Macs and UNIX.
Additional links have been added in the tools page, notably to
the Weizmann Institute ultra-fast rigorous (Smith/Waterman) similarity searches
using the Bioccelerator
and to the Garnier, Osgoodthorpe and Robson
structure prediction method at SBDS.
The SeqAnalRef database now includes a
section listing author's email and
eventually also WWW home pages. It is also possible to access the links from
a page displaying either a reference list or a single reference.
Amos has recently started to create a list of
Biomolecular servers for his own usage, but as some people have asked to
access this list (which is under construction), we are making it
available from the ExPASy top page.
Many other small changes were carried out in the last two months.
We thank you for using ExPASy (we
have now reached a cumulative total of 4 million connections).
- December 14, 1995
After 29 months of existence the ExPASy molecular biology server received a new logo, designed and produced by
- October 23, 1995
The Melanie page has been reorganised.
With the announcement of release 2.1 of the Melanie II
2-D PAGE analysis software package, a complete up-to-date
description of the software as well as a comprehensive tutorial are now
- October 13, 1995
Links have been added between SWISS-PROT Escherichia coli K12 chromosomal
entries and the EcoCyc
database, the encyclopedia of E. coli Gene and Metabolism.
You can now seach in PROSITE by citation.
- October 9, 1995
Some new features of ExPASy:
- Search in SWISS-PROT by citation -
When you call this option, you are prompted to enter the name of a journal and
optionally a volume number and/or a year. The program is written in such a way
that you can enter either the full name of a journal or its official abbreviation.
- RandSeq -
a new tool to generate random protein sequences.
- SWISS-PROT document haeinflu.txt -
Index of Haemophilus influenzae RD chromosomal entries and gene names with
links to the TIGR and EMBL servers.
- SWISS-PROT document submit.txt -
Description of how to submit sequence data to the SWISS-PROT data bank.
- SWISS-PROT document aatrnasy.txt -
List of aminoacyl tRNA synthetases.
- Swiss-Jokes -
A new page to give access to our collection of jokes from the fields of
molecular biology and of computing.
Many other changes have been done, such as the redesign of the
Geneva local pages; the addition, in the
tool page, of a link to ProfileScan.
It should also be noted that when you search in SWISS-PROT by either
or by full text
and that your seach criteria returns more than two entries, you can save these
entries to a file on our anonymous FTP server (in the outgoing
- September 19, 1995
New options - AACompIdent is a tool which allows the
identification of a protein from its
amino acid composition. It searches SWISS-PROT for proteins, whose amino
acid compositions are closest to the amino acid composition given. A
new option and a new constellation have been added to this tool:
A. Tagging option
With this option, the first 40 amino acid of each protein are printed in
the result, instead of the protein name. One may optionnally also enter a
tag (a short seuqnece, typically 3 to 8 residues) which will be matched with
the sequences of the resulting proteins. Proteins matching the tag will be
B. Free constellation
This is a free constellation, that is one may select any amino acid
constellation he/she likes. One just have to fill in the composition
values for the selected amino acids. The values will then be normalised,
so that the total make 100 (percent).
- September 4, 1995
A new page has been created: WORLD-2DPAGE is an
index to all known federated 2-D PAGE database servers, as well as to
2-D PAGE related servers and services.
- July 22, 1995
A new tool has been implemented on ExPASy, ProtParam
allows the computation of various physical and chemical parameters for a given
protein stored in SWISS-PROT or for a user entered sequence. The computed
parameters include the molecular weight, theoretical pI, amino acid composition,
extinction coefficient, estimated half-life, instability index and aliphatic
The Journal of Biological Chemistry (JBC) has a WWW server where abstracts and
full text of articles are made available. We are happy to announce the
implementation of what we believe to be the first direct link in a sequence
database between a reference and the full text version of a cited article.
Recent JBC references are directly linked to the corresponding entry point in
the JBC server. If you want to see such a link, take a look at reference 3 in
SWISS-PROT entry KDSA_ECOLI.
The SWISS-PROT document file jourlist.txt which
provides information on all the journals cited in that database, now contains
links to WWW or Gopher servers set up by a variety of publishers of academic
Two new SWISS-PROT document have been added, one is a nomenclature and index
of peptidase sequences, the other
is the list of Yeast Chromosome VI
entries in SWISS-PROT
- June 19, 1995
A new tool has been implemented on ExPASy, ScanProsite allows to either scan
a protein sequence the occurence of patterns stored in the PROSITE database
or to scan the SWISS-PROT database - including weekly releases - for the
occurence of a pattern.
We are happy to announce a new ""service"" Swiss-Quiz
The principle of this quiz is to answer to 10 randomly chosen questions
relative to the fields of molecular biology, biochemistry and genetics.
Each month, we will randomly pick up one person among all those that have
obtained a perfect score (and it's not so easy !) and will send that person
some delicious Swiss chocolate !
Links have been added from SWISS-PROT to the Saccharomyces genomic database
(SacchDb) at Stanford.
A new SWISS-PROT document has been added, it is a nomenclature and index of
- May 26, 1995
A new service is available:
The Two-Dimensional Gel Electrophoresis Laboratory of Geneva, Switzerland,
is running a highly reproducible method for the two-dimensional separation
of proteins. The laboratory now provides a 2-D PAGE service to which you
may send your samples for analysis. This service includes analytical and
preparative high-resolution 2-D PAGE, electrotransfer on membranes and/or
amino acid composition.
- May 17, 1995
New link in the Tools page to the multiple sequence alignment
at Washington University.
- May 11, 1995
Two links have been added to the SWISS-PROT entries. The first one
directly submits a request to Swiss-Model for a 3D model of the current SWISS-PROT
protein. The result is then sent back by e-mail. The second one allows to
perform a sequence alignment with the current sequence, using
NCBI's Basic Local Alignment Search Tool. This link is especially interesting
in the virtual SWISS-PROT entries produced by the
- May 5, 1995
We announce a new service, SWISS-FLASH,
that reports news of databases, software and services developments from the Swiss biocomputing groups responsible for the
ECD, ENZYME, LISTA, PROSITE, SeqAnalRef, SWISS-2DPAGE, SWISS-3DIMAGE and SWISS-PROT databases; the Melanie
software package; the WWW ExPASy server; the SWISS-Model, SWISS- Shop and other network-based computational tools; and the
SWISS-2DSERVICE services. If you subscribe to this service, you will automatically get the SWISS-Flash bulletins by electronic mail.
The SWISS-3DIMAGE database has been
completely reorganised and indexed. The database is now searchable
in the same way as the other SWISS-*** databases. We now also supply pictures in
JPEG format, in addition to GIF and SGI. The images may still be downloaded by FTP.
Links to REBASE points now the version maintained at John Hopkins, whose
layout is nicer than our own text based version !
- April 19, 1995
We added Translate, a new tool which allows the
translation of a nucleotide (DNA/RNA) sequence to a protein sequence.
Most of the pages in the server have been "refreshed" to make them more
- March 21, 1995
Links have been added from SWISS-PROT to the LISTA database of budding yeast
(Saccharomyces cerevisiae) genes coding for proteins prepared under the
supervisation of Patrick Linder.
- March 7, 1995
Links have been added from SWISS-PROT to the HSSP database of structure-sequence
alignments from the Protein Design Group, EMBL, Heidelberg.
- March 2, 1995
During the last two months, various links have been added:
- from SWISS-PROT to the SubtiList and YEPD databases
- from ENZYME to PROSITE and to the Ligand database in Kyoto
- internally from PROSITE entries to other relevant PROSITE entries
Links from SWISS-PROT to FlyBase use the new WWW server for that database.
Many new SWISS-PROT documents
have been added.
The page on the Melanie 2-D PAGE analysis
has been completely redesigned and includes now a on-line tutorial,
as well as a request for information form.
- December 7, 1994
In order to help users navigate through the ExPASy server, we have added
graphical examples. More will be added in the future. See for example:
Celegans examples or the
who's who on ExPASy page. Thanks
to Brigitte Boeckmann for the illustrations.
- October 31, 1994
the ENZYME Data Bank has been added to the ExPASy server.
This database may be accessed by EC number, name, compound, cofactor,
comment, or by browsing through the list of classes, subclasses and
sub-subclasses. Any entry in SWISS-PROT that contains an
EC number in the DE line has also a direct link to ENZYME (by clicking on
the EC number).
- October 20, 1994
Swiss-Shop - a sequence allerting system for Swiss-Prot that allows
you to automatically obtain new sequence entries relevant to your
field(s) of interest.
Swiss-Model - an automated knowledge-based protein modelling server.
the tool to compute pI and Mw now accepts also a list of ID/AC's.
SWISS-PROT: in PDB cross-reference lines, there is now a link
called RASMOL, sending the PDB entry as a chemical / pdb MIME type.
On Unix systems, if you add, in the file .mailcap in your home directory,
a line of the form
chemical/pdb; rasmol %s
then RASMOL will automatically be launched to display the protein 3D structure.
This works also with any other program which accepts PDB coordinates.
On systems other than Unix, this may also be specified. See your browser's manual.
- October 13, 1994
- The SWISS-PROT
top page has been re-modeled.
A number of new functionalities and documents have been added.
- October 7, 1994
- New tools have been added:
- Amino acid composition similarity search -
the search may now also be performed from a given SWISS-PROT entry,
whose amino acid composition will be compared with the whole SWISS-PROT
- Compute pI/Mw -
Compute the theoretical pI and Mw from a SWISS-PROT ID
or AC, or for a given sequence.
- October 5, 1994
- The gels run during
the 2-D PAGE courses in Geneva are now displayed on the server.
- September 29, 1994
protein maps now have a pI/Mw scale.
the Sequence Analysis Bibliographic Reference database has been added
to the ExPASy server. This database may be accessed by keyword, by reference
identifier, by author and by full text search.
List of on-line experts:
in SWISS-PROT and PROSITE top pages, a list of
on-line experts gives you the possibility to directly send questions to any
of the listed experts. The list is ogranized by subjects.
SWISS-PROT: new lists added:
- List of abbreviations for journals cited
- List of species has been made active
- Yeast Chromosome III entries in SWISS-PROT
- Nomenclature of extracellular domain
- List of on-line experts
new 3D line with active links to PDB.
- September 26, 1994
- In the tool
for identifying a protein by its amino acid composition, options have been
added. They allow to specify how many proteins should be displayed, as
well as the pI and Mw range in which the search should be performed.
Also, some old bugs have now been corrected.
- September 12, 1994
- The tool
for identifying a protein by its amino acid composition, has been corrected
and is now supposed to work. If you still encounter problems, please send
us a mail.
- June 17, 1994
- SWISS-PROT: added cross-references (DR lines) to GenBank.
- June 16, 1994
- SWISS-PROT: added cross-references (DR lines) to MaizeDB
Maize Genome Database of the National Agricultural Library.
- June 6, 1994
- Added the PROSITE page: PROSITE entries
may now be searched by description of sites and pattern, by accession number,
by author, and soon by full text search.
- June 3, 1994
- Added the GuessProt tool to the tools page:
you may now get the SWISS-PROT proteins closest to a given pI and
- May 27, 1994
- In SWISS-PROT entries, added links to GCRDb - the
G-Protein--Coupled Receptor DataBase.
Added the list of nomenclature related
references for proteins
to the SWISS-PROT top page.
- May 26, 1994
- Added a new reference 2-D PAGE map of Platelet
- May 20, 1994
- The SWISS-2DPAGE team is now organizing a
2-D PAGE training
in Geneva once every three months.
- May 18, 1994
- Added the Yeast Chromosome XI list of proteins to the SWISS-PROT
- May 11, 1994
- Tools: new page giving access to on-line analysis tools, such as
BLAST, BLITZ, PROSITE search and amino acid composition analysis, and more to come
in the future.
- March 23, 1994
- Added the list of restriction enzymes and methylases in SWISS-PROT
- March 22, 1994
- The ExPASy WWW server has been upgraded to a SPARCServer 10/51.
It should perform much faster now. If some features are not working,
please tell us about.
- March 18, 1994
- The links to OMIM are now direct links to the OMIM hypertext
server from GDB. Thanks to Keith Robison for informing me about it.
- March 4, 1994
- SWISS-2DPAGE: Added experimental Amino Acid Composition
you enter a protein's amino acid composition and the server will e-mail you
the list of SWISS-PROT entries with similar compositions,
sorted by decreasing similarity measure.
- March 2, 1994
- Added direct link to NCBI's BLAST Basic Local Alignment
Search Tool (ExPASy and SWISS-PROT top pages).
- March 1, 1994
- Starting with release 28, SWISS-PROT keyword search
will be performed on the main release as well as on the weekly updates.
In the SWISS-PROT page, added links to four additional active lists:
- Index of Escherichia coli K12 chromosomal entries in SWISS-PROT and their
corresponding EcoGene cross-reference
- Index of Saccharomyces cerevisiae entries in SWISS-PROT and their
corresponding gene designations
- Index of Caenorhabditis elegans entries in SWISS-PROT and their
corresponding gene designations and WormPep cross-references
- Index of Dictyostelium discoideum entries in SWISS-PROT and their
corresponding gene designations and DictyDB cross-references
- February 23, 1994
- Added two new reference 2-D PAGE maps: Macrophage Like Cell Line
(U937) and Erythroleukemia Cell (ELC).
In a SWISS-2DPAGE entry, it is now possible to compute the
theoretical pI and Mw of the protein.
- February 14, 1994
- Added SWISS-2DPAGE Map Selection: you select a 2-D PAGE
click on a spot and get information on the corresponding protein. See
the SWISS-2DPAGE top page.
- February 11, 1994
- Added a new reference 2-D PAGE map of Cerebrospinal Fluid
- January 28, 1994
- Added the bionet newsgroups.
- January 25, 1994
- Added an entry to SWISS-3DIMAGE images of crystallized proteins.
In SWISS-PROT entries which contain cross-references to PDB, added
a cross-reference to SWISS-3DIMAGE. Try for example
- January 24, 1994
- Added full text search of the SWISS-PROT protein
- January 17, 1994
- Added links to MEDLINE entries in SWISS-PROT,
through NCBI's Entrez Server.
Added, in the SWISS-2DPAGE page, a link to
the QUEST Protein Database Center.
- December 1, 1993
- Added a User Survey.
Please help us inprove the server in participating to this survey.
Added a new reference 2-D PAGE map of Lymphoma to SWISS-2DPAGE.
- November 23, 1993
- Added link to BioBit 24, the BIO-NAUT Newsletter from November,
22, 1993, describing the World Wide Web.
- November 18, 1993
- Added links to the Maize Genome Database at Columbia, Missouri
and to EMBnet Switzerland.
- November 17, 1993
- Added the list of overall Top Ten users in the
ExPASy server Activity Reports page.
- November 16, 1993
- Added Images of crystallized proteins from this server.
Added links to Harvard Biological Laboratories,
the Gene-Server at University of Houston,
the EMBnet: Biocomputing in Europe,
the biology servers index at USGS,
Jackson Laboratory WWW server and
Keith Robison's Molecular Biology WWW sampler.
- October 12, 1993
- Added a list of specialised documents to the SWISS-PROT top
page, such as 7-transmembrane G-linked receptors, CD nomenclature for
surface proteins of Human leucocytes and Vertebrate homeobox proteins.
Some of these list give then direct access to corresponding SWISS-PROT
- October 8, 1993
- Added links to the Caenorhabditis elegans
and Mycobacterium databases
at INRA (France).
Added a link to the ExPASy server activity reports.
- October 4, 1993
- Moved to the NCSA server.
- September 28, 1993
- Added the PDB Brookhaven Protein Data Bank of 3D structures.
In SWISS-PROT, cross-references to PDB have now
active links to the gopher server at Protein Data Bank. You may access
the PDB entry or get the 3D
image. Try for example the SWISS-PROT entry P00782.
- September 27, 1993
- Added the FlyBase database of genetic and molecular data for
Drosophila. In SWISS-PROT and EMBL, cross-references to FLYBASE
are now active links. Therefore, SWISS-PROT has now active links to
SWISS-2DPAGE, EMBL, PROSITE, REBASE, OMIM and FLYBASE. EMBL has active links
to SWISS-PROT and FlyBase.
- September 23, 1993
- Added a link to the National Institute of Health Genobase server to our top page.
- September 21, 1993
- Announced the ExPASy server and SWISS-2DPAGE release 0 to bionet.announce.
- August 1, 1993
- Installed the ExPASy molecular biology server, release 0, beta version.